Results 11 to 20 of about 203,949 (292)

High Glucose Induces Reactivation of Latent Kaposi's Sarcoma-Associated Herpesvirus [PDF]

Journal of Virology, 2016
ABSTRACT A high prevalence of Kaposi's sarcoma (KS) is seen in diabetic patients. It is unknown if the physiological conditions of diabetes contribute to KS development. We found elevated levels of viral lytic gene expression when Kaposi's sarcoma-associated herpesvirus (KSHV)-infected cells were cultured in high-glucose medium ...
Yan Zeng, Tiffany Jones, Jingfeng Sha, Kurt Kuhne, Charles E. Wood, Shou-Jiang Gao, Shou-Jiang Gao, Fengchun Ye, Fengchun Ye   +8 more
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Early childhood infection of Kaposi's sarcoma‐associated herpesvirus in Zambian households: A molecular analysis [PDF]

International Journal of Cancer, 2012
AbstractSub‐Saharan Africa is endemic for Kaposi's sarcoma‐associated herpesvirus (KSHV) and there is a high rate of early childhood infection; however, the transmission sources are not well characterized. We examined household members as potential KSHV transmission sources to young children in the KSHV‐endemic country of Zambia.
Olp, Landon, Shea, Danielle M., White, Maxine K., Gondwe, Clement, Kankasa, Chipepo, Wood, Charles   +5 more
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Antiretroviral Therapy for HIV-Associated Cutaneous Kaposi's Sarcoma: Clinical, HIV-Related, and Sociodemographic Predictors of Outcome

AIDS Research and Human Retroviruses, 2021
Kaposi's sarcoma (KS) is an AIDS-defining malignancy that can improve or worsen with antiretroviral therapy (ART). We aimed at identifying clinical, HIV-related, and sociodemographic factors associated with either progression or nonprogression (regression or stable disease) of ART-treated HIV-associated KS in patients with limited cutaneous disease. We
Ngalamika, Owen, Munsaka, Sody, Lidenge, Salum J, West, John T, Wood, Charles   +4 more
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HHV8 associated Kaposi’s sarcoma during triple immunosuppressive treatment with cyclosporin A, azathioprine, and prednisolone for ocular Behçet’s disease and complete remission of both disorders with interferon α [PDF]

Annals of the Rheumatic Diseases, 2001
Behcet’s disease is a multisystem vasculitis with oral and genital aphthous ulcers, cutaneous vasculitis, uveitis, and arthritis as its main features. 1 Ocular manifestations, especially panuveitis, have a poor prognosis, resulting in blindness in most patients after five years, irrespective of treatment.
Manfred Zierhut, V Gärtner, B Bültmann, N Stübiger, F Graepler, A K Eckstein, R Kandolf, Lothar Kanz, C Aepinus, B Kaskas, Ina Kötter   +10 more
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Mycosis fungoides and Kaposi’s sarcoma association in an HIV-negative patient [PDF]

Anais Brasileiros de Dermatologia, 2016
The association of mycosis fungoides and kaposi’s sarcoma in HIV-negative patients is a rare phenomenon. The presence of human herpesvirus 8 (HHV-8) – associated with all forms of Kaposi’s sarcoma – has also been recently identified in mycosis fungoides ...
Maria Carolina Prado Fleury Bariani, Luiz Fernando Fróes Fleury Júnior, Ana Maria Quinteiro Ribeiro, Siderley de Souza Carneiro, Tiago Arantes Pereira   +4 more
doaj   +1 more source

Enhancement of Autophagy during Lytic Replication by the Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Activator [PDF]

Journal of Virology, 2010
ABSTRACT Autophagy is one of two major degradation systems in eukaryotic cells. The degradation mechanism of autophagy is required to maintain the balance between the biosynthetic and catabolic processes and also contributes to defense against invading pathogens.
Wen, Hui-Ju, Yang, Zhilong, Zhou, You, Wood, Charles   +3 more
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Comparing six cardiovascular risk prediction models in Haiti: implications for identifying high-risk individuals for primary prevention

BMC Public Health, 2022
Background Cardiovascular diseases (CVD) are rapidly increasing in low-middle income countries (LMICs). Accurate risk assessment is essential to reduce premature CVD by targeting primary prevention and risk factor treatment among high-risk groups ...
Lily D. Yan, Jean Lookens Pierre, Vanessa Rouzier, Michel Théard, Alexandra Apollon, Stephano St Preux, Justin R. Kingery, Kenneth A. Jamerson, Marie Deschamps, Jean W. Pape, Monika M. Safford, Margaret L. McNairy   +11 more
doaj   +1 more source

Targeting Kaposi’s sarcoma associated herpesvirus encoded protease (ORF17) by a lysophosphatidic acid molecule for treating KSHV associated diseases

Frontiers in Cell and Developmental Biology, 2023
Kaposi’s sarcoma associated herpesvirus (KSHV) is causative agent of Kaposi’s sarcoma, Multicentric Castleman Disease and Pleural effusion lymphoma. KSHV-encoded ORF17 encodes a protease which cleaves -Ala-Ala-, -Ala-Ser- or -Ala-Thr-bonds.
Misbahuddin M Rafeeq, Alaa Hamed Habib, Alaa F. Nahhas, Najat Binothman, Majidah Aljadani, Jawaher Almulhim, Ziaullah M Sain, Mohammad Zubair Alam, Mohammad Zubair Alam, Norah A Alturki, Qamre Alam, Manish Manish, Rajnish Kumar Singh   +12 more
doaj   +1 more source

A case of Kaposi’s sarcoma of tonsil with profuse bleeding in an HIV-positive patient

SAGE Open Medical Case Reports, 2021
Kaposi’s sarcoma is the most common AIDS-associated malignancy. Kaposi’s sarcoma in the oral cavity and oropharynx present as a macular, papular, or nodular lesion on the palate, gingiva, or tongue which may look pink, reddish, or purplish.
Dorji Penjor, Aun Wee Chong
doaj   +1 more source

Conjunctival Kaposi’s sarcoma in Acquired Immunodeficiency Syndrome (AIDS) patient: a case report

Indonesia Journal of Biomedical Science, 2020
Background: Kaposi’s sarcoma (KS) is malignant neoplasm of the vascular endothelium, caused by Human Herpes Virus 8 (HHV 8). Clinical variants consist of classic KS, iatrogenic KS, and AIDS KS. The manifestation of KS in the eye may occur in the eyelids, the lacrimal sac or gland, the orbit and bulbar or palpebral conjunctiva. This case study aims to
Ni Made Laksmi Utari, I Made Susila Utama, I Made Agus Kusumadjaja, Putu Yuliawati, Anak Agung Ayu Sukartini Djelantik, Elbetty Simanjutak   +5 more
openaire   +1 more source