Results 61 to 70 of about 203,949 (292)

Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis

Nature Communications, 2021
Antibiotic therapy can lead to pathogen clearance, but also to alterations in the gut microbiota and systemic immune responses. Here, the authors analyze data from patients with tuberculosis and healthy subjects to show that pathogen clearance and gut ...
Matthew F. Wipperman, Shakti K. Bhattarai, Charles Kyriakos Vorkas, Venkata Suhas Maringati, Ying Taur, Laurent Mathurin, Katherine McAulay, Stalz Charles Vilbrun, Daphie Francois, James Bean, Kathleen F. Walsh, Carl Nathan, Daniel W. Fitzgerald, Michael S. Glickman, Vanni Bucci   +14 more
doaj   +1 more source

Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma.

Proceedings of the National Academy of Sciences of the United States of America, 1999
Human herpesvirus 8 (HHV-8, also called KSHV) is linked to the etiopathogenesis of Kaposi's sarcoma (KS), multicentric Castleman's disease (MCD), and primary effusion lymphoma (PEL). The universal presence of HHV-8 in early KS has not yet been shown.
Nicolas Dupin, C. Fisher, P. Kellam, S. Ariad, M. Tulliez, N. Franck, E. V. Marck, D. Salmon, I. Gorin, J. Escande, R. Weiss, K. Alitalo, C. Boshoff   +12 more
semanticscholar   +1 more source

Dermatological Malignancies at a University Teaching Hospital in north-western Tanzania: A Retrospective Review of 154 Cases [PDF]

, 2012
Dermatological malignancies are among the most common form of cancers and the global incidence has been increasing at an alarming rate. A retrospective study was conducted to determine the prevalence, histopathological pattern, anatomical distribution ...
Chalya, Phillipo L., Gilyoma, Japhet M., Kahima, Kahima J., Kanumba, Emmanuel S., Masalu, Nestory, Mawala, Brian, Rambau, Peter   +6 more
core   +2 more sources

Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells.

Proceedings of the National Academy of Sciences of the United States of America, 2005
MicroRNAs (miRNAs) are an endogenously encoded class of small RNAs that have been proposed to function as key posttranscriptional regulators of gene expression in a range of eukaryotic species, including humans.
Xuezhong Cai, Shihua Lu, Zhihong Zhang, Carlos M. González, B. Damania, B. Cullen   +5 more
semanticscholar   +1 more source

Familial Kaposi’s Sarcoma: A Report of Five Cases from Greece

Case Reports in Dermatological Medicine, 2014
Introduction. Familial cases of Kaposi’s sarcoma have rarely been reported. Kaposi’s sarcoma is not uncommon in Greece; its incidence is estimated at 0.20 per 100.000 habitants, showing an increased predominance in the Peloponnese, in Southern Greece ...
Kalliopi Armyra, Anargyros Kouris, Arsinoi Xanthinaki, Alexandros Stratigos, Irene Potouridou   +4 more
doaj   +1 more source

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future [PDF]

, 2015
Constitutively activated prosurvival pathways render cancer cells addicted to their effects. Consequently they turn out to be the Achilles’ heels whose inhibition can be exploited in anticancer therapy.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TRIVEDI, PANKAJ   +6 more
core   +4 more sources

Prevalence and correlates of Kaposi's sarcoma-associated herpesvirus infection in a sample of men who have sex with men in eastern China

Epidemiology and Infection, 2012
SUMMARYThis study aimed to determine the seroprevalence of Kaposi's sarcoma-associated herpesvirus (KSHV) and related factors in men who have sex with men (MSM) in China. A total of 208 subjects were recruited from eastern China from 2008 to 2009. Plasma samples were collected and screened for KSHV, HIV and syphilis. Overall, KSHV seroprevalence was 32·
Charles E. Wood, Hualiang Lin, Hualiang Lin, Tao Zhang, Veenu Minhas, W. Zhu, N He   +6 more
openaire   +3 more sources

Hemorragia digestiva alta por Sarcoma de Kaposi en paciente con VIH-SIDA

Galicia Clínica, 2021
Gastrointestinal bleeding related to Kaposi’s Sarcoma is rare in AIDS patients; the etiology of anemia is usually multifactorial. We describe the case of a HIV infected, 53 year old patient with refractory anemia requiring frequent transfusion support ...
Ana Carolina Freitas Ferreira, Vanessa Barcelos, Ana Raquel Garrote, Alexandra Caeiro   +3 more
doaj   +1 more source

A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus.

Proceedings of the National Academy of Sciences of the United States of America, 1998
Herpesviruses exist in two states, latency and a lytic productive cycle. Here we identify an immediate-early gene encoded by Kaposi's sarcoma-associated herpesvirus (KSHV)/human herpesvirus eight (HHV8) that activates lytic cycle gene expression from the
R. Sun, Su-Fang Lin, L. Gradoville, Yan Yuan, F. Zhu, G. Miller   +5 more
semanticscholar   +1 more source

KSHV G-protein coupled receptor vGPCR oncogenic signaling upregulation of Cyclooxygenase-2 expression mediates angiogenesis and tumorigenesis in Kaposi’s sarcoma

PLOS Pathogens, 2020
Kaposi's sarcoma-associated herpesvirus (KSHV) vGPCR is a constitutively active G protein-coupled receptor that subverts proliferative and inflammatory signaling pathways to induce cell transformation in Kaposi's sarcoma. Cyclooxygenase-2 (COX-2) is an inflammatory mediator that plays a key regulatory role in the activation of tumor angiogenesis. Using
Qi Ma, Chiara Chiozzini, Chiara Chiozzini, Daiana Sapochnik, Daiana Sapochnik, Julian Naipauer, Elizabeth Hyjek, Elizabeth Hyjek, Enrique A. Mesri, C. B. Cymeryng, Pilar Eroles, Omar A. Coso, Omar A. Coso, Omar A. Coso, Ethel Cesarman, Agata D´Agostino, María Victoria Medina, María Victoria Medina, María Victoria Medina, Lucas E. Cavallin   +19 more
openaire   +9 more sources