Results 31 to 40 of about 30,022 (126)

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

A 37‐Year Retrospective Analysis Reveals a High Rate of Cutaneous Angiosarcoma of the Scalp in Okinawa, Japan

open access: yesCancer Science, Volume 116, Issue 4, Page 1059-1067, April 2025.
A 37‐year retrospective analysis has revealed an exceptionally high rate of angiosarcoma of the scalp in Okinawa, Japan. This study represents the first identification of Okinawa as a hotspot for this rare cancer, the epidemiology of which has been insufficiently studied.
Aoi Ohira   +7 more
wiley   +1 more source

Penile Kaposi sarcoma: A case of complete resolution with highly active antiretroviral therapy alone [PDF]

open access: yes, 2011
Kaposi sarcoma remains an important cause of morbidity in HIV-infected patients. Regardless of the recent pharmacological progress, treatment of this malignancy is still disappointing.
Alves, R.   +6 more
core   +1 more source

The S‐Phase Arrest of Host Cells Caused by an Alpha‐Herpesvirus Genome Replication Facilitates Viral Recruitment of RNA Polymerase II to Transcribe Viral Genes

open access: yesCell Proliferation, EarlyView.
Viral infection arrests host cells in the S phase, which promotes vDNA synthesis and vRC formation, further facilitating viral recruitment of RNA Pol II to preferentially transcribe viral genes. ABSTRACT Herpesviruses rely on host RNA polymerae II (RNA Pol II) for their mRNA transcription, yet the mechanisms of which has been poorly defined, while ...
Qiqi Yang   +16 more
wiley   +1 more source

HIV and cancer registry linkage identifies a substantial burden of cancers in persons with HIV in India. [PDF]

open access: yes, 2016
We utilized computerized record-linkage methods to link HIV and cancer databases with limited unique identifiers in Pune, India, to determine feasibility of linkage and obtain preliminary estimates of cancer risk in persons living with HIV (PLHIV) as ...
Bhatia, Kishor   +13 more
core   +1 more source

A Cutaneous Vascular Neoplasm With an EWSR1‐NFATC2 Translocation—Contributing to the Spectrum of Vascular Lesions Characterized by NFATC‐Related Fusions

open access: yesJournal of Cutaneous Pathology, Volume 52, Issue 6, Page 410-413, June 2025.
ABSTRACT Recently, a distinct subgroup of vascular neoplasms has been identified, characterized by NFATC‐related fusions. Although existing literature is limited, these lesions histologically show a variable appearance with a tendency for local recurrence but not distant spread.
B. Schurink   +3 more
wiley   +1 more source

Dermatological Lesions of Cholesterol Embolization Syndrome and Kaposi Sarcoma Mimic Primary Systemic Vasculitis: Case Report Study [PDF]

open access: yes, 2022
Primary systemic vasculitis can present with a wide spectrum of manifestations ranging from systemic non-specific features such as fever, malaise, arthralgia, and myalgia to specific organ damage.
Ahmed, Amal A   +7 more
core   +1 more source

Remembering the forgotten child: the role of immune checkpoint inhibition in patients with human immunod eficiency virus and cancer. [PDF]

open access: yes, 2019
Patients with human immunodeficiency virus (HIV) infection have a high risk of developing virally-mediated cancers. These tumors have several features that could make them vulnerable to immune checkpoint inhibitors (ICIs) including, but not limited to ...
Adashek, Jacob J   +3 more
core  

Fatal outcome in classic Kaposi's sarcoma [PDF]

open access: yes, 2010
First described in 1872, Kaposi's sarcoma is defined as a rare multifocal tumor that originates in the endothelial cells and presents with cutaneous and extracutaneous manifestations. The classic form is most common in elderly men and progression is slow.
Almeida, Fernando Augusto de   +4 more
core   +3 more sources

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