HIV-1 Evolutionary Patterns Associated with Metastatic Kaposi's Sarcoma during AIDS. [PDF]
Kaposi's sarcoma (KS) in HIV-infected individuals can have a wide range of clinical outcomes, from indolent skin tumors to a life-threatening visceral cancer. KS tumors contain endothelial-related cells and inflammatory cells that may be HIV-infected. In
Barbier, Andrew E+6 more
core +4 more sources
Plaque‐Like Dermatofibroma: A Case Report and a Review of the Literature With a Focus on Dermoscopy
ABSTRACT Plaque‐like dermatofibroma (PLDF) is a rare clinical variant of dermatofibroma (DF), characterised by flat, infiltrative lesions, often larger than 50 mm in diameter and located on the trunk or lower extremities. A 44‐year‐old male presented to our clinic with a 20 cm brownish plaque with peripheral satellite lesions on the right antecubital ...
Francesco Cavallo+7 more
wiley +1 more source
Angiogenesis, Kaposi’s sarcoma and Kaposi’s sarcoma-associated herpesvirus [PDF]
Tumor angiogenesis is the uncontrolled growth of blood vessels in tumors, serving to supply nutrients and oxygen, and remove metabolic wastes. Kaposi's sarcoma (KS), a multifocal angioproliferative disorder characterized by spindle cell proliferation, neo-angiogenesis, inflammation, and edema, is associated with infection by Kaposi's sarcoma-associated
Shou-Jiang Gao+6 more
openaire +3 more sources
Diagnostic dilemma in Kaposi’s sarcoma
Kaposi′s sarcoma is described as cutaneous and extracutaneous neoplasm predominantly affecting older individuals. Though earlier uncommon and endemic to certain African areas, its incidence is on a rise due to infections with human immunodeficiency virus
Rao B.S Satish+4 more
doaj +1 more source
Discovery of Kaposi’s sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA
Significance Human herpesviruses are known to interact with non-protein encoding RNAs like microRNAs and long noncoding RNAs. Circular RNAs (circRNAs) are recently discovered noncoding RNAs that are long-lived and resistant to exonucleases, and that bind
Takanobu Tagawa+10 more
semanticscholar +1 more source
Remembering the forgotten child: the role of immune checkpoint inhibition in patients with human immunod eficiency virus and cancer. [PDF]
Patients with human immunodeficiency virus (HIV) infection have a high risk of developing virally-mediated cancers. These tumors have several features that could make them vulnerable to immune checkpoint inhibitors (ICIs) including, but not limited to ...
Adashek, Jacob J+3 more
core
Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
BM Friedman+51 more
core +2 more sources
Rare Case of Vallecular Hemangioma With Complete Regression in an Adult Patient
A rare case of spontaneous regression of a pedunculated vallecular hemangioma in a 55‐year‐old male is presented. Following an incisional biopsy, the lesion regressed completely within three weeks, confirmed by imaging and direct laryngoscopy. This case highlights an unusual clinical outcome and raises questions about the mechanisms underlying ...
Guilherme Reimann Agne+8 more
wiley +1 more source
The article describes the clinical observation of Kaposi sarcoma associated with HIV in a patient with disseminated pulmonary tuberculosis, viral hepatitis B and C.
N. V. Nelidova+3 more
doaj +1 more source
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara+7 more
core +2 more sources