Results 1 to 10 of about 159,246 (160)
The amphioxus genome and the evolution of the chordate karyotype
Nature, 2008 Lancelets (‘amphioxus’) are the modern survivors of an ancient chordate lineage, with a fossil record dating back to the Cambrian period. Here we describe the structure and gene content of the highly polymorphic ∼520-megabase genome of the Florida ...
Nicholas H Putnam +2 more
exaly +2 more sources
Pervasive chromosomal instability and karyotype order in tumour evolution
Nature, 2020 Eva Grönroos +2 more
exaly +2 more sources
The Turner syndrome life course project: Karyotype‐phenotype analyses across the lifespan
Clinical Endocrinology, 2017 Antoinette Cameron-pimblett +2 more
exaly +2 more sources
Nature Genetics, 2021 Central to tumor evolution is the generation of genetic diversity. However, the extent and patterns by which de novo karyotype alterations emerge and propagate within human tumors are not well understood, especially at single-cell resolution.
Yannik Bollen +25 more
semanticscholar +1 more source
Analysis of muntjac deer genome and chromatin architecture reveals rapid karyotype evolution
Communications Biology, 2020 Closely related muntjac deer show striking karyotype differences. Here we describe chromosome-scale genome assemblies for Chinese and Indian muntjacs, Muntiacus reevesi (2 n = 46) and Muntiacus muntjak vaginalis (2 n = 6/7), and analyze their evolution
Austin B. Mudd +4 more
semanticscholar +1 more source
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.
New England Journal of Medicine, 2005 BACKGROUND Nucleophosmin (NPM), a nucleocytoplasmic shuttling protein with prominent nucleolar localization, regulates the ARF-p53 tumor-suppressor pathway.
B. Falini +22 more
semanticscholar +1 more source
Scallop genome provides insights into evolution of bilaterian karyotype and development
Nature Ecology &Evolution, 2017 Reconstructing the genomes of bilaterian ancestors is central to our understanding of animal evolution, where knowledge from ancient and/or slow-evolving bilaterian lineages is critical. Here we report a high-quality, chromosome-anchored reference genome
Shi Wang +54 more
semanticscholar +1 more source
The wax gourd genomes offer insights into the genetic diversity and ancestral cucurbit karyotype
Nature Communications, 2019 The botanical family Cucurbitaceae includes a variety of fruit crops with global or local economic importance. How their genomes evolve and the genetic basis of diversity remain largely unexplored.
Dasen Xie +17 more
semanticscholar +1 more source