Results 71 to 80 of about 77,988 (331)

Wnt Inhibition Safeguards Porcine Embryonic Stem Cells From the Acquisition of Extraembryonic Endoderm Cell Fates

Advanced Science, EarlyView.
The study reports that Wnt inhibitors safeguard porcine embryonic stem cells (ESCs) from acquiring the extraembryonic endoderm (XEN) lineage, and further develop an efficient strategy to derive XEN cells from ESCs. The XEN cells from ESCs exhibit similar transcriptome and chromatin accessibility features to XEN cells from embryos and contribute to ...
Hanning Wang, Liang Zhong, Zhuangfei Wang, Jinzhu Xiang, Duanqing Pei   +4 more
wiley   +1 more source

Adult patients with Ph+ ALL benefit from conditioning regimen of medium‐dose VP16 plus CY/TBI

Hematological Oncology, Volume 40, Issue 5, Page 1041-1055, December 2022., 2022
Abstract The medium‐dose etoposide (VP16) added on cyclophosphamide (CY)/total body irradiation (TBI) is one of the intensified myeloablative conditioning regimens used in allogenic hematopoietic stem cell transplantation (allo‐HSCT) for acute lymphoblastic leukemia (ALL).
Mari Morita‐Fujita, Yasuyuki Arai, Tadakazu Kondo, Kaito Harada, Naoyuki Uchida, Takashi Toya, Yukiyasu Ozawa, Takahiro Fukuda, Shuichi Ota, Makoto Onizuka, Yoshinobu Kanda, Yumiko Maruyama, Satoru Takada, Toshiro Kawakita, Takahide Ara, Tatsuo Ichinohe, Takafumi Kimura, Yoshiko Atsuta, Shinichi Kako   +18 more
wiley   +1 more source

Cytogenetic study of the giant otter Pteronura brasiliensis Zimmermann 1780 (Carnivora, Mustelidae, Lutrinae)

Genetics and Molecular Biology, 2007
The giant otter, Pteronura brasiliensis Zimmermann 1780 (Carnivora, Mustelidae, Lutrinae), was widely distributed in South America but stable populations are now only found in the Pantanal and Amazon regions and the species is classified as endangered ...
Jorge Felipe Oliveira Franco-de-Sá, Fernando César Weber Rosas, Eliana Feldberg   +2 more
doaj   +1 more source

Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder [PDF]

, 2016
From 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD) for monogenetic disorder, 3 human embryonic stem cells (hESCs) HVR1, HVR2 and HVR3 were successfully derived.
Aguilera, Yolanda, Antiñolo Gil, Guillermo, Hmadcha, Abdelkrim, Lozano Arana, María Dolores, Mellado, Nuria, Moya, Cristina, Palacios Calvo, José, Soria Escoms, Bernat, Sánchez Palazón, Luis, Sánchez, Javier   +9 more
core   +2 more sources

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile Rotundata Reveals Its Ecological Adaptation and Pollination Biology

Advanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi, Pan Duan, Mengmeng Zhu, Rong Zhang, Zihua Zhao, Xin Nie, Hanhou He, Li Hou, Xianhui Wang   +8 more
wiley   +1 more source

Socioeconomic position and clinical outcomes in patients with myelodysplastic syndromes: A population‐based cohort study

Hematological Oncology, Volume 40, Issue 5, Page 1056-1066, December 2022., 2022
Abstract Low socioeconomic position (SEP) may be associated with adverse outcomes in patients with myelodysplastic syndromes (MDS) inherent to for example, delayed diagnosis or reduced treatment intensity, but firm evidence is limited. In this study, we examined the association between SEP and clinical outcomes.
Tine Bichel Lauritsen, Lene Sofie Granfeldt Østgård, Kirsten Grønbæk, Susanne Oksbjerg Dalton, Jan Maxwell Nørgaard   +4 more
wiley   +1 more source

Chromosomal Evolution in the Phylogenetic Context: A Remarkable Karyotype Reorganization in Neotropical Parrot Myiopsitta monachus (Psittacidae)

Frontiers in Genetics, 2020
Myiopsitta monachus is a small Neotropical parrot (Psittaciformes: Arini Tribe) from subtropical and temperate regions of South America. It has a diploid chromosome number 2n = 48, different from other members of the Arini Tribe that have usually 70 ...
Ivanete de Oliveira Furo, Ivanete de Oliveira Furo, Ivanete de Oliveira Furo, Rafael Kretschmer, Rafael Kretschmer, Patricia Caroline O’Brien, Jorge C. Pereira, Analía del Valle Garnero, Ricardo José Gunski, Rebecca E. O’Connor, Darren Karl Griffin, Anderson José Baia Gomes, Malcolm Andrew Ferguson-Smith, Edivaldo Herculano Correa de Oliveira, Edivaldo Herculano Correa de Oliveira, Edivaldo Herculano Correa de Oliveira   +15 more
doaj   +1 more source

Cytological study of Allium cepa and Allium sativum [PDF]

, 2017
The large number of species in the Allium genus has necessitated comparative analysis of related species which has always been used in many cases to describe patterns and directions of chromosomal evolution within a group.
Akpan, U. U., Awe, E. T.
core  

FISH-aimed karyotype analysis in Aconitum subgen : aconitum reveals excessive rDNA sites in tetraploid taxa [PDF]

, 2018
The location of 5S and 35S rDNA sequences in chromosomes of four Aconitum subsp. Aconitum species was analyzed after fluorescence in situ hybridization (FISH). Both in diploids (2n = 2x = 16; Aconitum variegatum, A. degenii) and tetraploids (2n = 4× = 32;
Grabowska-Joachimiak, Aleksandra, Hasterok, Robert, Joachimiak, Andrzej, Musiał, Krystyna, Sliwinska, Elwira   +4 more
core   +2 more sources

On the Transcriptomic Signature and General Stress State Associated with Aneuploidy [PDF]

arXiv, 2020
Whether aneuploid cells with diverse karyotypes have any properties in common has a been a subject of intense interest. A recent study by Terhorst et al. (1) reinvestigated the common aneuploidy gene expression (CAGE), disputing the conclusion of our recent work (2).
arxiv