Results 221 to 230 of about 42,553 (305)

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Phylogenetic Analysis and Karyotype Evolution in Two Species of Core Gruiformes: Aramides cajaneus and Psophia viridis. [PDF]

Genes (Basel), 2020
Furo IO, Kretschmer R, O'Brien PCM, Pereira JC, Ferguson-Smith MA, de Oliveira EHC.   +5 more
europepmc   +1 more source

Hematopathology Practice in the Digital Era: What has Changed?

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematopathology workflows are complex, since they include numerous data points necessary for guiding further testing, diagnosis, and patient management. The workflows start with complete blood cell counts, with subsequent morphologic evaluation of peripheral blood (PB) and bone marrow (BM).
Olga Pozdnyakova
wiley   +1 more source

Significance of Myelodysplasia‐Related Mutations and the Genetic Landscape of Acute Leukemias of Ambiguous Lineage

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT The recent fifth edition WHO classification and ICC classification systems have moved further toward genetically defined classifications of acute leukemias. Both now recognize myelodysplasia‐related (MR) mutations as defining of MDS‐related AML (AML‐MR).
Timothy J. Kirtek, Olga K. Weinberg
wiley   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Comparative analyses of three swallow species (Aves, Passeriformes, Hirundinidae): Insights on karyotype evolution and genomic organization. [PDF]

Genet Mol Biol, 2020
Barcellos SA, Kretschmer R, Souza MS, Costa AL, Degrandi TM, Lopes CF, Ferguson-Smith MA, Pereira J, Oliveira EHC, Gunski RJ, Garnero ADV.   +10 more
europepmc   +1 more source

Requirements for Human Cerebral Organoids

Cell Proliferation, EarlyView.
Ya‐Jie Xu, Chun‐Hui Duan, Tie‐Shan Tang, Yu‐Kai Wang, Weihong Song, Bo‐Qiang Fu, Ai‐Jin Ma, Bao‐Yang Hu, Zhen‐Ge Luo, Xiao‐Qing Zhang, Yan Liu, Zhao‐Qian Teng, Jie Hao, Qiang Wei, Zhi‐Hong Wu, Yong Zhang, Bing Zhao, Shan Bian, Jing‐Zhong Zhang, Bo Peng, Tian‐Qing Li, Yue‐Jun Chen, Jing Liu, Lei Wang, Yang Zhao, Wei‐Qi Zhang, Yao‐Jin Peng, Bo‐Ya Zhang, Xin‐Jie Bao, Yan‐Lin Wang, Yi Tang, Shi‐Jun Hu, Qian Li, Gao‐Xiang Zhu, Alex Zhang, Lijun Zhu, Qi‐Yuan Li, Tao Na, Lin Zhao, Yi‐Fang Ping, Hong‐Ling Zhao, Shuai‐Shuai Niu, Qi Zhou, Tong‐Biao Zhao, Chang‐Mei Liu   +44 more
wiley   +1 more source

Diagnosing Systemic Mastocytosis: State of the Art

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley   +1 more source

Lessons from clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, EarlyView.
Fuki Marie Hisama
wiley   +1 more source

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source