Results 41 to 50 of about 43,706 (302)
Stem Cell Research, 2021 Complete Androgen Insensitivity Syndrome (CAIS) is a difference of sex development (DSD) caused by loss of function of the androgen receptor (AR) gene. Patients typically identify as female and have a 46,XY karyotype.
Grace B. Schwartz +2 more
doaj +1 more source
High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells. [PDF]
, 2017 Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) offers the possibility of studying the molecular mechanisms underlying human diseases in cell types difficult to extract from living patients, such as neurons and cardiomyocytes.
Arias, Angelo +12 more
core +2 more sources
BMC Genetics, 2008 Background In this study we examined the karyotypes of morphologically indistinguishable populations of the electric knifefish Gymnotus carapo sensu stricto from the Eastern Amazon of Brazil.
De Souza Augusto CP +6 more
doaj +1 more source
Comparative Cytogenetics, 2017 We provide the first karyotype description of the agro-predatory ant species Megalomyrmex incisus Smith, 1947 (Myrmicinae, Formicidae), and chromosome counts of its host Mycetophylax conformis (Mayr, 1884) (Myrmicinae, Formicidae) from geographically ...
Danon Clemes Cardoso +3 more
doaj +3 more sources
When karyotype is decisive for myelodysplastic syndromes diagnosis
Hematology, Transfusion and Cell Therapy, 2019 Introduction: The myelodysplastic syndromes (MDS) are a group of heterogeneous clonal hematopoietic stem cell disorders that results in peripheral blood (PB) cytopenias and bone marrow (BM) dysplasia.
Aline dos Santos Borgo Perazzio +1 more
doaj +1 more source
A case of intersex occurrence in Steindachneridion parahybae (Steindachner, 1877) (Siluriformes: Pimelodidae) under captivity condition: A cytogenetic and morphological study [PDF]
, 2016 Poco se sabe sobre la biología reproductiva de Steindachneridion parahybae , una especie de teleósteo gonocorístico en peligro de extinción que habita la cuenca del río Paraíba do Sul y en éste trabajo se describe por primera vez la aparición de ...
Caneppele, Danilo +4 more
core +2 more sources
Establishment and characterization of two human breast carcinoma cell lines by spontaneous immortalization: Discordance between Estrogen, Progesterone and HER2/neu receptors of breast carcinoma tissues with derived cell lines [PDF]
, 2012 Background: Breast cancer is one of the most common cancers among women throughout the world. Therefore, established cell lines are widely used as in vitro experimental models in cancer research.Methods: Two continuous human breast cell lines, designated
Akmal, S.N. +6 more
core +1 more source
PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites
Advanced Science, EarlyView.This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang +13 more
wiley +1 more source
Comparative Cytogenetics, 2014 Chromosome counts and karyotypes of two species of Chrysolaena H. Robinson 1988 are presented in this paper. Mitotic analysis revealed that both taxa have x=10, a basic chromosome number considered characteristic of the genus.
Gisela Via do Pico +1 more
doaj +1 more source
Advanced Science, EarlyView.Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian +5 more
wiley +1 more source