Results 221 to 230 of about 37,774 (292)

Hormonal Therapy Before Micro‐TESE in Men With Nonobstructive Azoospermia: A Negative Answer to an Overly Broad Question

Andrology, EarlyView.
Sandro C. Esteves, Arnold P. P. Achermann, Ricardo Miyaoka, Cassio L. Z. Riccetto, Adriano Fregonesi   +4 more
wiley   +1 more source

Increase in fetal haemoglobin from baseline to day 10 is a biomarker for response to decitabine in AML: Results of the AML21 randomized phase III trial of the EORTC Leukemia Group, Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) and German MDS Study Group

British Journal of Haematology, EarlyView.
Summary Lack of response or delayed response to therapy are major challenges in the use of DNA‐hypomethylating agents (HMA) in patients with acute myeloid leukaemia (AML). Fetal haemoglobin (HbF) is a potential biomarker for response to HMA treatment but has only been studied in small single‐centre studies.
Julia Stomper, Michal Kicinski, Tobias Ma, Thomas Meyer, Sylvain Chantepie, Richard Noppeney, Mario Luppi, Ernesta Audisio, Laimonas Griškevičius, Andreas Neubauer, Robin Foà, Walter J. F. M. Van der Velden, Anna Candoni, Radovan Vrhovac, Gianluca Gaidano, Catharina Van Elssen, Mels Hoogendoorn, Maurizio Musso, Attilio Olivieri, Christian Junghanß, Emmanuel Bissé, Stephanie Antunes, Frédéric Baron, Adriano Venditti, Joop H. Jansen, Pierre W. Wijermans, Gerwin Huls, Michael Lübbert   +27 more
wiley   +1 more source

Genetic etiology and phenotypic characteristics of fetuses with 11q deletion syndrome (11q23.3-q25). [PDF]

Exp Ther Med
Zhang T, Cong X, Li Z, Cao X, Hu L, Luo X, Liu Y, Liu W, Wei F.   +8 more
europepmc   +1 more source

Author's Response: Can Hormonal Therapy Improve the Outcomes of mTESE in Patients with Nonobstructive Azoospermia?

Andrology, EarlyView.
M. Anfosso, M. Schubert, JF. Cremers, S. Kliesch, M. Zitzmann, S. Bier   +5 more
wiley   +1 more source

Whole-exome sequencing increases variant detection compared to karyotyping and CMA in an unselected FGR cohort. [PDF]

Sci Rep
Liu J, Lin K, Mai Z, Zhang Y, Li X, Meng X, Chen H.   +6 more
europepmc   +1 more source

Prenatal and Postnatal Identification of Phelan-McDermid Syndrome in a Tertiary Referral Center: A 15-Case Series and Literature Review. [PDF]

J Clin Med
Xue H, Dai Y, Ye X, Zhang L, Guo Q, Lin N, Huang H, Xu L.   +7 more
europepmc   +1 more source

Whole‐genome and transcriptome analysis in relapsed/refractory non‐Hodgkin lymphoma: Results from a multicentre precision oncology cohort

British Journal of Haematology, EarlyView.
Summary Comprehensive genome and transcriptome profiling can inform the diagnosis, prognosis and management of relapsed/refractory (R/R) solid malignancies, yet its integration into clinical care has lagged despite strong biological rationale. We evaluated the clinical utility of whole genome and transcriptome analysis (WGTA) in 65 patients (37 ...
Kathleen Wee, Eric J. Zhao, Cassidy Clemente‐Jones, Rebecca J. Deyell, Shahrad R. Rassekh, Anita Villani, Rosemarie Venier, Daniel Sinnett, Sylvie Langlois, Thai Hoa Tran, Thomas Sontag, Stephanie Grover, Scott Davidson, Nisha Kanwar, Winnie Lo, Erin Pleasance, Laura Williamson, Yaoqing Shen, Alina S. Gerrie, Kerry J. Savage, Laurie H. Sehn, Christopher P. Venner, Marco A. Marra, Janessa Laskin, Diego Villa   +24 more
wiley   +1 more source

A qPCR-based algorithm for the diagnosis of classic and non-classic Turner syndrome. [PDF]

Indian J Med Res
Bose C, Mondal S, Saha C, Sengupta N, Bhattacharyya NP, Mukhopadhyay S.   +5 more
europepmc   +1 more source

Deep Phenotyping in ReNU Syndrome Identifies a Recognizable Age‐Dependent Clinical Trajectory

Clinical Genetics, EarlyView.
Longitudinal evaluation of 11 individuals with ReNU syndrome revealed an age‐dependent multisystem trajectory. This longitudinal description may help clinicians anticipate changing needs in feeding, growth, neurological, visual, communication, behavioral, and orthopedic care. ABSTRACT Pathogenic variants in the noncoding gene RNU4‐2 cause ReNU syndrome,
Nadja Pekkola Pacheco, Malin Kvarnung, Anna Hammarsjö, Daniel Nilsson, Bianca Tesi, Britt Marie Anderlid, Giedre Grigelioniene, Maria Johansson Soller, Liselot van der Laan, Charlotte Willfors, Charlotta Ingvoldstad Malmgren, Anna Lindstrand, Tommy Stödberg, Ann Nordgren, Angelica Maria Delgado‐Vega   +14 more
wiley   +1 more source

Comprehensive assessment of the genomic stability of human induced pluripotent stem cells for clinical applications. [PDF]

Stem Cell Res Ther
Zhang K, Na T, Jia C, Yuan X, Guo M, Yang X, Li M, Jia W, Bai Z, Lu J, Liu Z, Meng S.   +11 more
europepmc   +1 more source