Results 41 to 50 of about 37,774 (292)

Karyotyping human chromosomes by optical and X-ray ptychography methods [PDF]

, 2014
Sorting and identifying chromosomes, a process known as karyotyping, is widely used to detect changes in chromosome shapes and gene positions. In a karyotype the chromosomes are identified by their size and therefore this process can be performed by ...
Xiong, G, Robinson, IK, Yusuf, M, Shemilt, LA, Verbanis, E, Estandarte, AK, Zhang, F, Schwenke, J, Parmar, N   +8 more
core  

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

Advanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang, Junxiang Ji, Baoxing Dong, Zhenhua Zhu, Xucheng Lv, Peng Chen, Wenqiang Liu, Min Zhou, Shou‐Dong Ye   +8 more
wiley   +1 more source

Karyotyping mouse chromosomes by multiplex-FISH (M-FISH).

, 2001
Karyotyping of mouse chromosomes is a skillful art, which is laborious work even for experienced cytogeneticists. With the growing number of mouse models for human diseases, there is an increasing demand for automated mouse karyotyping systems.
Adler, I.-D., Carter, N.P., Jentsch, I., Speicher, M.R.   +3 more
core   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

DNA repetitive probes and trinucleotide sequences used for FISH karyotyping.

, 2017
DNA repetitive probes and trinucleotide sequences used for FISH karyotyping.
Gabriella Linc (3390143), Ekaterina Badaeva (527616), Márta Molnár-Láng (338817), Eszter Gaál (3826777), István Molnár (260473), Diana Icsó (3826780)   +5 more
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Computer assisted fish karyotyping

, 2019
Fish karyotyping plays an important role in studies of cytotaxonomy and chromosomic evolution of species. However, few semi or completely automated fish karyotyping systems are available.
D.R. Blanco (6546287), C.R.M. Mauricio (6546281), J.C. Klock (6546278), F.K. Schneider (6546284)   +3 more
core   +1 more source

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation

Advanced Science, EarlyView.
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu, Jialu Kang, Qi Ye, Zixi Wang, Lei Li, Yuzeshi Lei, Leihong Ye, Tianjie Liu, Bin Wang, Tao Liu, Shan Xu, Ke Wang, Yong Zhang, Jian Ma, Lei Li   +14 more
wiley   +1 more source

Prevalence of Down’s Syndrome in Patients of Congenital Heart Disease in Vidarbha Region Central India [PDF]

International Journal of Anatomy Radiology and Surgery, 2017
Introduction: Down’s syndrome is a genetic state in which a person has 47 chromosomes instead of 46, with an additional copy of chromosome number 21. This additional genetic material disorders the normal growth process leading to medical and physical
Anant C Fulse, Md. Saleem Md. Basheer, Dilip D Ksheersagar, Vishwajit M Paikrao   +3 more
doaj   +1 more source

Selective karyotyping in recurrent miscarriage: are recommended guidelines adopted in daily clinical practice?

, 2011
Contains fulltext : 97344.pdf (Publisher’s version ) (Open Access)BACKGROUND: Couples with recurrent miscarriage (RM) have an increased risk of one of the partners carrying a structural chromosome abnormality.
F. van der Veen, A. C. Knegt, Kremer, J.A.M., H. R. Verhoeve, Boogaard, E. van den, Verhoeve, H.R., J. A. M. Kremer, Knegt, A.C., Veen, F. van der, Goddijn, M., E. van den Boogaard, R. P. M. G. Hermens, M. Goddijn, Hermens, R.P.M.G.   +13 more
core   +1 more source