Results 61 to 70 of about 142,560 (388)
Онкогематология, 2022 Cytogenetic changes in bone marrow cells and their influence on clinical course of the disease were analyzed in 106 patients with acute non-lymphoblastic leukemia (ANLL).
A. M. Vakulchuk +4 more
doaj +1 more source
Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognisable syndrome [PDF]
, 2010 Background The introduction of molecular karyotyping technologies facilitated the identification of specific genetic disorders associated with imbalances of certain genomic regions.
Bena, F +23 more
core +2 more sources
Advanced Science, EarlyView.RAD21L1 is upregulated in human Sertoli cells to be transited to become spermatogonial stem cells by overexpressing DAZ family three genes. RAD21L1 is sufficient and effective for reprogramming Sertoli cells into human spermatogonial stem cells with high safety through DNA methylation.
Caimei He +4 more
wiley +1 more source
Swyer Syndrome in Phenotypic Female with 46,XY Karyotype [PDF]
Journal of Clinical and Diagnostic Research, 2018 Individuals with Swyer syndrome have an XY karyotype and are phenotypically female. The prevalence of Swyer Syndrome is about 1 in 30,000 and it is an extremely rare condition.
D Prashanth Shetty +3 more
doaj +1 more source
Analyzing a clinical case of married couple with combined infertility
Акушерство, гинекология и репродукция, 2022 Infertility is a disease of the reproductive system characterized by lacked clinical pregnancy after 12 or more months of regular unprotected sex. To diagnose the causes and choose the tactics of infertility treatment, a personalized approach to each ...
A. V. Ledina, G. G. Ketova
doaj +1 more source
Lifespan‐Regulated CAR‐Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy
Advanced Science, EarlyView.Using a tamoxifen‐inducible Hoxb8 system, proliferative bone marrow progenitors can be generated, which are subsequently engineered with an anti‐CEA CAR construct containing a suicide gene (iCas9) and differentiated into CAR‐macrophages. This method facilitates scale up the production of CAR‐macrophages.
Chuancheng Gao +8 more
wiley +1 more source
Advanced Science, EarlyView.PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li +6 more
wiley +1 more source
Chromosomal abnormalities in primary and secondary amenorrhea
Bangabandhu Sheikh Mujib Medical University JournalBackground: Menstruation is an important physiological function of the female reproductive system. The absence of menstruation is called amenorrhea. Many genetic and nongenetic causes are responsible for primary or secondary amenorrhea. This study aimed
Tasnim Binte Ahmed +3 more
doaj +1 more source
Czech Journal of Genetics and Plant Breeding, 2015 The mitotic chromosomes of Lablab purpureus (L.) Sweet were characterised using sequential combined propidium iodide (PI) and 4',6-diamidino-2-phenylindole (DAPI) (CPD) staining and fluorescence in situ hybridisation (FISH) with 5S and 45S rDNA probes ...
Chao-Wen SHE, Xiang-Hui JIANG
doaj +1 more source
Towards many colors in FISH on 3D-preserved interphase nuclei [PDF]
, 2006 The article reviews the existing methods of multicolor FISH on nuclear targets, first of all, interphase chromosomes. FISH proper and image acquisition are considered as two related components of a single process.
Albiez, H. +9 more
core +1 more source