Results 51 to 60 of about 1,455,846 (152)

Image_2_Case report: Experience of a rare case of rebound of the Kasabach-Merritt phenomenon during sirolimus treatment in kaposiform hemangioendothelioma.JPEG

, 2022
Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm associated with the Kasabach–Merritt phenomenon (KMP), which is a consumptive coagulopathy with associated potentially life-threatening thrombocytopenia.
Liang Wang (23021), Zhuang Liu (551357), Lei Guo (36221), Jing Li (10611), Yanli Niu (4165657), Changhua Wu (13202715), Dan Song (644313), Jie Zhou (28945)   +7 more
core   +1 more source

Successful Management of Neonatal and Infantile Kaposiform Hemangioendothelioma with Low-Dose Sirolimus Therapy

Journal of Pediatrics: Clinical Practice
Sirolimus is reportedly effective for kaposiform hemangioendothelioma. However, data on the efficacy of low-dose sirolimus therapy remain limited. This report presents two cases of neonatal and infantile kaposiform hemangioendothelioma associated with ...
Yoshimasa Uematsu, MD, Ken-ichiro Konishi, MD, PhD, Kiyoshi Tanaka, MD, PhD, Hajime Takayasu, MD, PhD, Eiichiro Watanabe, MD, PhD, Takuji Tomari, MD, Hitoshi Isohata, MD, Hidehiko Nakanishi, MD. PhD, Daigo Ochiai, MD, PhD, Yusuke Kumamoto, MD, PhD   +9 more
doaj   +1 more source

Cavernous Haemangioma with Kasabach-Merritt Syndrome: Treatment with Alpha-Interferon

, 1996
A small number of patients with haemangioma need treatment for serious complications such as Kasabach-Merritt syndrome, cardiac failure and obstruction of the airway. We report on the management of an infant with Kasabach-Merritt syndrome.
H S Joffe, P J Fleming, J J Ettlinger, C T C Kennedy   +3 more
core   +1 more source

Kasabach-Merritt syndrome complicating a giant hemangioma of the liver: A case report

, 2023
Liver hemangiomas are the most common benign tumors of the liver with a prevalence of 1%-20% according to autopsy series. They can in some cases reach measurable sized.
N. Moatassim Billah, PhD, I. El Messaoudi, MD, N. Rguieg, MD, K. Imrani, MD, N. Amsiguine, MD, S. El Houss, MD, I. Nassar, PhD   +6 more
core   +1 more source

An Examination of Sirolimus's Role in Endothelial Cells of Kaposiform Haemangioendothelioma

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT Kaposiform haemangioendothelioma (KHE) research faces challenges due to the lack of established cell lines and suitable animal models. Our study aimed to establish KHE cell lines, spheroids and refine murine models to mimic disease characteristics, advancing our understanding of KHE pathogenesis and exploring novel therapies. Primary KHE cells
Yanan Li, Chuan Wang, Meng Kong, Li Li, Yi Ji   +4 more
wiley   +1 more source

Kasabach-Merritt Syndrome

, 2002
Background: Kasabach-Merritt syndrome (KMS) is a consumptive coagulopathy associated with the presence of a large vascular lesion. It is often a frustrating condition to treat and it carries a high mortality rate.
Sheilagh Maguiness, Lyn Guenther
core   +1 more source

Metastatic angiosarcoma and Kasabach-Merritt syndrome [PDF]

, 2014
Angiosarcomas are exceedingly rare tumors that are often difficult to diagnose. Exceptionally unusual is the presentation of these tumors with Kasabach-Merritt Syndrome, a curious form of intratumoral coagulation that can be impossible to distinguish ...
Munis, Aun, Edward Romond, Jessica Moss, Moss, Jessica, Romond, Edward, Massarweh, Suleiman, Suleiman Massarweh, Aun Munis, Karabakhtsian, Rouzan, Rouzan Karabakhtsian   +9 more
core   +1 more source

Congenital Kaposiform Hemangioendothelioma With Kasabach-Merritt Phenomenon Successfully Treated With Low-Dose Radiation Therapy

, 2014
Kaposiform hemangioendothelioma (KHE) associated with Kasabach-Merritt phenomenon is a life-threatening vasculopathy. The current mainstay treatment for KHEs is corticosteroids and chemotherapy, but these medications do not work for all patients and ...
Malhotra, Yogangi, Antaya, Richard J, Yang, Catherine S, McNamara, Joseph   +3 more
core   +1 more source

Image_1_Case report: Experience of a rare case of rebound of the Kasabach-Merritt phenomenon during sirolimus treatment in kaposiform hemangioendothelioma.JPEG

, 2022
Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm associated with the Kasabach–Merritt phenomenon (KMP), which is a consumptive coagulopathy with associated potentially life-threatening thrombocytopenia.
Liang Wang (23021), Zhuang Liu (551357), Lei Guo (36221), Jing Li (10611), Yanli Niu (4165657), Changhua Wu (13202715), Dan Song (644313), Jie Zhou (28945)   +7 more
core   +1 more source

Congenital hemangiomas with transient neonatal thrombocytopenia: case reports and review of the literature

Frontiers in Pediatrics
Congenital hemangioma with thrombocytopenia is rare and is often mistaken for Kasabach-Merritt phenomenon seen in kaposiform hemangioendothelioma.
Yuan-yang Zheng, Jiajie Lv, Xiaoxi Lin, Chen Hua   +3 more
doaj   +1 more source