Effects of Kathon, a Chemical Used Widely as a Microbicide, on the Survival of Two Species of Mosquitoes [PDF]
Molecules, 2021 In recent decades, demands for novel insecticides against mosquitoes are soaring, yet candidate chemicals with desirable properties are limited. Kathon is a broad-spectrum isothiazolinone microbicide, but other applications remain uncharacterized. First,
Wen-Ze He +5 more
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Patch tests and hand eczema: retrospective study in 173 patients and literature review [PDF]
Anais Brasileiros de Dermatologia, 2023 Background Hand eczema (HE) is a highly prevalent, recurrent, and multifactorial disease. It encompasses a group of eczematous diseases that affect the hands, etiologically classified into irritant contact dermatitis (ICD), allergic contact dermatitis ...
Nathalie Mie Suzuki +4 more
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Preservative Contact Hypersensitivity among Adult Atopic Dermatitis Patients [PDF]
Life, 2022 Atopic dermatitis (AD) is a chronic inflammatory disease characterised by an impaired skin barrier. The prolonged use of topical preparations containing medications, emollients, fragrances and preservatives may increase the risk of contact ...
Dominik Németh +3 more
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Isothiazolinones as Novel Candidate Insecticides for the Control of Hemipteran Insects [PDF]
Antibiotics, 2021 Hemipteran insects, such as whiteflies, aphids and planthoppers, resemble one of the most important pest groups threating food security. While many insecticides have been used to control these pests, many issues such as insecticide resistance have been ...
Wenze He +3 more
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Kathon Induces Fibrotic Inflammation in Lungs: The First Animal Study Revealing a Causal Relationship between Humidifier Disinfectant Exposure and Eosinophil and Th2-Mediated Fibrosis Induction [PDF]
Molecules, 2020 Currently available toxicity data on humidifier disinfectants are primarily limited to polyhexamethylene guanidine phosphate-induced lung fibrosis.
Mi-Kyung Song, Dong Im Kim, Kyuhong Lee
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Absence of Adverse Effects on Pulmonary Histopathology and Functions Following Inhalation Exposure to Chloromethylisothiazolinone/Methylisothiazolinone [PDF]
ToxicsIn South Korea, issues have been raised regarding exposure to humidifier disinfectant products containing certain chemicals postulated to induce lung diseases in consumers.
Sam Kacew, Esref Demir
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High rate of sensitization to Kathon CG, detected by patch tests in patients with suspected allergic contact dermatitis, [PDF]
Anais Brasileiros de Dermatologia, 2020 Background: Kathon CG, a combination of methylchloroisothiazolinone and methylisothiazolinone, is widely used as preservative in cosmetics, as well in household cleaning products, industrial products such as paints and glues.
Eliane Aparecida Silva +4 more
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Prevalence of reactive allergens in contact patch testing studies using the Brazilian standard battery: a systematic review [PDF]
Anais Brasileiros de DermatologiaBackground: Contact dermatitis is a common dermatosis in dermatology. The patch test is the gold standard for diagnosis, using a panel of common allergens and irritants. In Brazil, a standardized battery of 30 substances is used.
Ana Laura Andrade Bueno +2 more
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Usefulness of dermoscopy in the evaluation of patch test reactions, [PDF]
Anais Brasileiros de Dermatologia, 2022 Background: Despite being widely used in different areas of dermatology, there have been few studies evaluating the benefit of dermoscopy in the interpretation of patch tests, especially in weak and doubtful reactions.
Kenselyn Oppermann +2 more
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IL-9 and IL-24 biomarkers in the transcriptional signature of contact dermatitis to methylisothiazolinone [PDF]
Frontiers in ImmunologyIntroductionAllergic contact dermatitis (ACD) is a cutaneous inflammatory disorder mediated by allergen-specific memory T cells. Methylisothiazolinone (MI), a preservative widely used in industrial and cosmetic products and a component of Kathon CG, has ...
Taynah Cohen de Melo +10 more
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