Results 21 to 30 of about 20,581 (189)

Neuroprotective Kaurane Diterpenes from Fritillaria ebeiensis [PDF]

Bioscience, Biotechnology, and Biochemistry, 2011
The new kaurane diterpene, ent-3β-butanoyloxykaur-15-en-17-ol, and four known kaurane diterpenes were isolated from the bulbs of Fritillaria ebeiensis. Their structures were elucidated on the basis of extensive spectroscopic analyses (IR, ESI-MS, HR-ESI-MS, 1-D and 2-D NMR).
Jing Xu, Ping-Xia Guo, Cuizhou Liu, Zhanping Sun, L. Gui, Yuanqiang Guo, T. Yamakuni, Y. Ohizumi   +7 more
semanticscholar   +3 more sources

Kaurane diterpenes from the fruits of Zanthoxylum leprieurii (Rutaceae) [PDF]

: The fruits of Zanthoxylum leprieurii Guill. & Perr. (Rutaceae) are traditionally used in Africa, particularly in Cameroon, as a spice and in the treatment of sickle cell anaemia.
Evans, AR, Guetchueng, ST, Ismail,, FM, Nahar, L, Ritchie, KJ, Sarker, SD, Wansi, JD   +6 more
core   +1 more source

The correlation among residual nitrites, biogenic amines, N‐nitrosamine formation, and degradation occurrence of punicalagin α/β, rosmarinic acid, carnosol, and carnosic acid in extract‐treated sausage during storage

Food Science &Nutrition, Volume 11, Issue 9, Page 5409-5426, September 2023., 2023
The use of natural antioxidants in meat products has been extensively studied. However, no reports have been found regarding the accumulation of antioxidant residues in meat products over the storage time in cold storage by LC‐DAD‐MS analysis. To manufacture of Punica granatum L.
Elahe Abedi, Atefeh Tavakoli, Simin Zamanizadeh, Shahrzad Maleki, Amir Reza Jassbi   +4 more
wiley   +1 more source

Plant terpene specialized metabolism: complex networks or simple linear pathways?

The Plant Journal, Volume 114, Issue 5, Page 1178-1201, June 2023., 2023
SUMMARY From the perspectives of pathway evolution, discovery and engineering of plant specialized metabolism, the nature of the biosynthetic routes represents a critical aspect. Classical models depict biosynthesis typically from an end‐point angle and as linear, for example, connecting central and specialized metabolism. As the number of functionally
Emily R. Lanier, Trine Bundgaard Andersen, Björn Hamberger   +2 more
wiley   +1 more source

Ferroptosis‐modulating small molecules for targeting drug‐resistant cancer: Challenges and opportunities in manipulating redox signaling

Medicinal Research Reviews, Volume 43, Issue 3, Page 614-682, May 2023., 2023
Abstract Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight cancer and overcome drug resistance in antitumor therapy. Understanding the molecular interactions and structural features of ferroptosis‐inducing compounds might ...
Solveigh C. Koeberle, Anna P. Kipp, Hermann Stuppner, Andreas Koeberle   +3 more
wiley   +1 more source

Risks for human health related to the presence of grayanotoxins in certain honey

EFSA Journal, Volume 21, Issue 3, March 2023., 2023
Abstract The European Commission asked EFSA for a scientific opinion on the risks for human health of the presence of grayanotoxins (GTXs) in ‘certain honey’ from Ericaceae plants. The risk assessment included all structurally related grayananes occurring with GTXs in ‘certain’ honey. Oral exposure is associated with acute intoxication in humans. Acute
EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Birgit Dusemund, Andrew Hart, Patrick Mulder, Barbara Viviani, Maria Anastassiadou, Claudia Cascio, Francesca Riolo, Heather Wallace   +24 more
wiley   +1 more source

Labdane conjugates protect cardiomyocytes from doxorubicin‐induced cardiotoxicity

Drug Development Research, Volume 84, Issue 1, Page 84-95, February 2023., 2023
Abstract The cardiovascular side effects associated with doxorubicin (DOX), a wide spectrum anticancer drug, have limited its clinical application. Therefore, to explore novel strategies with cardioprotective effects, a series of new labdane conjugates were prepared (6a–6c and 8a–8d) from the natural diterpene labdanodiol (1).
Irene Cuadrado, Sandra Oramas‐Royo, Laura González‐Cofrade, Ángel Amesty, Sonsoles Hortelano, Ana Estévez‐Braun, Beatriz de las Heras   +6 more
wiley   +1 more source

Network‐Based Method to Investigate the Promoted Cell Apoptosis Mechanisms of Oridonin in OSCC through the RNA‐Transcriptome

Journal of Immunology Research, Volume 2023, Issue 1, 2023., 2023
The morbidity of oral cancer is high in the world. Oridonin is a traditional Chinese medicine that can effectively inhibit oral squamous cell carcinoma (OSCC) growth, but its mechanism remains unclear. Our previous data showed that oridonin inhibited CAL‐27 cell proliferation and promoted apoptosis.
Guohui Wu, Yusheng Guo, Yang Liu, Xiangsheng Cai, Tanggang Deng, Tianchu Pei, Long Huang, Kai Chen, Xuan Pan, Jian Song   +9 more
wiley   +1 more source

Safety of the proposed amendment of the specifications for enzymatically produced steviol glycosides (E 960c): Rebaudioside D produced via enzymatic bioconversion of purified stevia leaf extract

EFSA Journal, Volume 20, Issue 5, May 2022., 2022
Abstract The EFSA Panel on Food Additives and Flavourings (FAF Panel) provides a scientific opinion on the safety of a proposed amendment of the specifications of enzymatically produced steviol glycosides (E 960c) with respect to the inclusion of rebaudioside D produced via enzyme‐catalysed bioconversion of purified stevia leaf extract. Rebaudioside D (
EFSA FAF Panel (EFSA Panel on Food Additives and Flavourings), Maged Younes, Gabriele Aquilina, Karl‐Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Rainer Gürtler, Ursula Gundert‐Remy, Trine Husøy, Melania Manco, Wim Mennes, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, José Manuel Barat Baviera, Gisela Degen, Lieve Herman, Jean‐Charles Leblanc, Detlef Wölfle, Jaime Aguilera, Alessandra Giarola, Camilla Smeraldi, Giorgia Vianello, Laurence Castle   +26 more
wiley   +1 more source

Phylogeny, Phytomedicines, Phytochemistry, Pharmacological Properties, and Toxicity of Croton gratissimus Burch (Euphorbiaceae)

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2022, Issue 1, 2022., 2022
Croton gratissimus is an important plant in Africa setup and across the globe for its ethnomedicinal uses in managing a wide range of diseases. Its phylogeny, pharmacological properties, ethnomedicinal uses, phytochemistry, and cytotoxicity have been highlighted in various articles and journals.
Kirkland Dingili Magwilu, Joseph Mwanzia Nguta, Isaac Mapenay, Dorine Matara, Srinivas Mutalik   +4 more
wiley   +1 more source