The Efficiency of Selected Green Solvents and Parameters for Polyphenol Extraction from Chokeberry (Aronia melanocarpa (Michx)) Pomace [PDF]
Foods, 2023 Chokeberry pomace is a potential source of natural colourants, antimicrobial agents, and anti-senescence compounds due to its high polyphenols content.
Efaishe Tweuhanga Angaleni Kavela +2 more
doaj +3 more sources
Leptospira Lipid A Is a Potent Adjuvant That Induces Sterilizing Immunity against Leptospirosis [PDF]
Vaccines, 2023 Leptospirosis is a globally significant zoonotic disease. The current inactivated vaccine offers protection against specific serovars but does not provide complete immunity.
Vivek P. Varma +3 more
doaj +3 more sources
LigA formulated in AS04 or Montanide ISA720VG induced superior immune response compared to alum, which correlated to protective efficacy in a hamster model of leptospirosis [PDF]
Frontiers in Immunology, 2022 Leptospirosis is a zoonotic disease of global importance. The current vaccine provides serovar-specific and short-term immunity and does not prevent bacterial shedding in infected animals.
Vivek P. Varma +8 more
doaj +3 more sources
Broad-spectrum antimicrobial activity and in vivo efficacy of SK1260 against bacterial pathogens [PDF]
Frontiers in MicrobiologyIntroductionAntimicrobial resistance (AMR) is a growing global health concern, necessitating the development of novel therapeutic agents. Antimicrobial peptides (AMPs) have emerged as promising candidates due to their broad-spectrum activity and lower ...
Sridhar Kavela +2 more
doaj +3 more sources
Ladin ve Kayın Masif Panel, MDFLam ve YLLam Malzemelerde Kavelalı ve Vidalı Birleştirmelerin Eğilme Moment Değerleri Üzerine Etkilerinin Karşılaştırılması [PDF]
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2019 Buçalışmada ahşap ve ahşap esaslı malzemelerde L-tipi köşe birleştirmelerineğilme moment değerleri üzerine etkileri araştırılmıştır. Bu amaçla ahşapmalzeme olarak Ladin ve Kayın masif paneller, ahşap esaslı malzeme olarakMDFLam (melamin kaplı orta ...
Nurdan Çetin Yerlikaya
doaj +3 more sources
Turkish Journal of Forestry, 2019 In this study, dowel tensile strength values of wooden length joints prepared using dowels obtained from ash (Fraxinus excelsior Lipsky), chestnut (Castanea sativa Mill.) and oak (Quercus petraea Lieble) were investigated.
Abdurrahman KARAMAN +2 more
doaj +4 more sources
Deciphering the Role of Leptospira Surface Protein LigA in Modulating the Host Innate Immune Response [PDF]
Frontiers in Immunology, 2021 Leptospira, a zoonotic pathogen, is known to infect various hosts and can establish persistent infection. This remarkable ability of bacteria is attributed to its potential to modulate (activate or evade) the host immune response by exploiting its ...
Ajay Kumar +9 more
doaj +3 more sources
Adjuvant activity of a small molecule TLR4 agonist discovered via structure-based virtual screening [PDF]
Communications BiologyMonophosphoryl lipid A (MPLA), a TLR4 agonist, is a clinically approved vaccine adjuvant, but its complex structure and occasional toxicity limit broader use.
Mohammad Kadivella +5 more
doaj +3 more sources
Use of an Integrated Multi-Omics Approach To Identify Molecular Mechanisms and Critical Factors Involved in the Pathogenesis of <i>Leptospira</i>. [PDF]
Microbiol Spectr, 2023 Leptospirosis is a zoonotic disease of global importance. It is caused by a Gram-negative bacterial spirochete of the genus Leptospira. ABSTRACT Leptospirosis, a bacterial zoonosis caused by pathogenic Leptospira spp., is prevalent worldwide and has ...
Kavela S +5 more
europepmc +2 more sources
Upregulation of Phosphatase 1 Nuclear-Targeting Subunit (PNUTS) Is an Independent Predictor of Poor Prognosis in Prostate Cancer. [PDF]
Dis Markers, 2020 Protein phosphatase 1 nuclear‐targeting subunit (PNUTS) is ubiquitously expressed and associates with PTEN and protein phosphatase 1 (PP1) to control its activity. The role of PNUTS overexpression has hardly been studied in cancer. In this study, we used immunohistochemistry to quantitate PNUTS expression on a tissue microarray containing 17,747 ...
Marx A +24 more
europepmc +2 more sources