Results 21 to 30 of about 381 (124)

Emerging evidence for CHFR as a cancer biomarker : from tumor biology to precision medicine [PDF]

, 2013
Novel insights in the biology of cancer have switched the paradigm of a "one-size-fits-all" cancer treatment to an individualized biology-driven treatment approach.
Azad, Nilofer, Brandes, Johann C, Cleven, Arjen HG, de Bruïne, Adriaan P, Derks, Sarah, Herman, James G, Melotte, Veerle, Smits, Kim M, Van Criekinge, Wim, van Engeland, Manon   +9 more
core   +8 more sources

Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties. [PDF]

Organic and biomolecular chemistry, 2013
B. Dulla, Krishna T. Kirla, V. Rathore, G. S. Deora, Sridhar Kavela, S. Maddika, Kiranam Chatti, O. Reiser, J. Iqbal, M. Pal   +9 more
semanticscholar   +2 more sources

WWP2 ubiquitin ligase and its isoforms: New biological insight and promising disease targets [PDF]

, 2011
A number of recent papers on the WWP2 E3 ubiquitin ligase and two novel WWP2 isoforms have revealed important biological insight and disease-specific functions, and also impacted on our understanding of ubiquitin ligases in cell cycle regulation ...
Chantry, A
core   +1 more source

Association Signals Unveiled by a Comprehensive Gene Set Enrichment Analysis of Dental Caries Genome-Wide Association Studies [PDF]

, 2013
Gene set-based analysis of genome-wide association study (GWAS) data has recently emerged as a useful approach to examine the joint effects of multiple risk loci in complex human diseases or phenotypes.
Cuenco, Karen T., Feingold, Eleanor, Jia, Peilin, Marazita, Mary L., Wang, Kai, Wang, Lily, Wang, Quan, Zeng, Zhen, Zhao, Zhongming   +8 more
core   +3 more sources

Farklı Ahşap Malzemelerden Elde Edilen Kavelalar İle Birleştirilmiş “L” Tipi Mobilya Köşe Birleştirmelerin Moment Taşıma Kapasitelerinin Belirlenmesi

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2019
Bu çalışmada, farklı ağaç malzemelerden elde edilen kavelalar kullanılarak hazırlanmış L-tipi mobilyabirleştirmelerinin moment taşıma kapasiteleri araştırılmıştır.
Abdurrahman Karaman, Mehmet Nuri Yıldırım   +1 more
doaj   +1 more source

Discovery of Small Molecule WWP2 Ubiquitin Ligase Inhibitors [PDF]

, 2018
We have screened small molecule libraries specifically for inhibitors that target WWP2, an E3 ubiquitin ligase associated with tumour outgrowth and spread.
Angulo, Aronchik, Cerami, Chantry, Chen, Gong, Kathman, Li, Maddika, Maspero, Mayer, Meiboom, Monaco, Mund, Pellecchia, Quirit, Rossi, Singh, Soond, Soond, Verdecia, Zou   +21 more
core   +1 more source

PTEN-lipid Binding Assay

Bio-Protocol, 2013
The lipid and protein interactions are an integral and important part of many cellular signaling pathways. The understanding of the selective and specific interaction of the given lipid molecule with the target protein is required for studying cellular ...
Sridhar Kavela, Swapnil Shinde, Subbareddy Maddika   +2 more
doaj   +1 more source

How ubiquitination regulates the TGF-β signalling pathway: New insights and new players [PDF]

, 2011
Ubiquitination of protein species in regulating signal transduction pathways is universally accepted as of fundamental importance for normal development, and defects in this process have been implicated in the progression of many human diseases.
Bai, Bengoechea-Alonso, Bernassola, Chen, Chen, Chen, Chiu, Ciechanover, Ciehanover, Coccetti, Cook, Cook, Corcoran, Dunn, Ebisawa, Fang, Finley, Flasza, Foot, Foster, Fukuchi, Fukuchi, Fuxe, Gao, Gao, Gazdoiu, Grenfell, Groettrup, Guedat, Haldeman, Handley-Gearhart, Hayashi, He, Hjerpe, Ho, Huang, Huang, Huang, Inoue, Jin, Kang, Kasanov, Kavsak, Kerscher, Koinuma, Komuro, Kuratomi, Li, Liao, Lin, Liu, Liu, Lu, Maddika, Miyazawa, Moren, Mukhopadhyay, Mund, Murata, Nakamura, Nakao, Ogunjimi, Orban, Pelzer, Petroski, Pickart, Pirozzi, Putters, Raikwar, Sadowski, Schmierer, Seo, Shook, Soond, Soond, Stephen, Summers, Sun, Sun, Suzuki, Tajima, Tatematsu, Thrower, Walden, Wan, Wan, Wan, Wendt, Wiesner, Xie, Xu, Xu, Zhang, Zhang, Zhu, Zou   +95 more
core   +1 more source

A Characterization of Strong and Weak Convergence in Fuzzy Metric Spaces [PDF]

, 2021
In this paper, we attempt to introduce the concept of fuzzy metric space and some of its properties, and we investigate the strong and weak convergence in fuzzy metric Spaces.
Md. Abdul Mannan Md. R. Rahman Halima Akter Momtaz Begum (Momo) Md. Amanat Ullah Samiran Mondal Md. Anisur Rahman
core   +2 more sources

The performance of 3d printed dowel with three different surface designs in furniture joints

Turkish Journal of Forestry
The shear strengths of the joints produced by using Poly Lactic Acid (PLA), PLA+ Thermoplastic Polyurethane (TPU), and resin (Acrylic Photopolymer) with three different surface design of the dowels including, grooved, straight, and cross were ...
Nazmiye Tuğçe Kuvel, Kutay Çava, Mustafa Aslan, Samet Demirel   +3 more
doaj   +1 more source