Results 11 to 20 of about 36,269 (228)

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode   +16 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

Kawasaki disease shock syndrome complicated by coronary aneurysms: a case report

open access: yesThe Pan African Medical Journal, 2021
Kawasaki disease is a generalized systemic vasculitis, which primarily affects medium-sized arteries. Kawasaki disease shock syndrome is a rare but severe presentation of this disease. This report describes a case of delayed diagnosis of Kawasaki disease
Ahmed Rassas   +4 more
doaj   +1 more source

Kawasaki Disease and Allergic Diseases [PDF]

open access: yesFrontiers in Pediatrics, 2021
Background: Kawasaki disease (KD) is an inflammatory disorder with an unknown etiology. It is the leading cause of acquired heart disease, which leads to coronary vasculitis among children. Studies of frequent manifestation of allergic diseases in children with KD have been the subject of mounting clinical interest.
Po-Yu Huang   +6 more
openaire   +3 more sources

Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review

open access: yesItalian Journal of Pediatrics, 2023
Background Kawasaki disease (KD) is a medium vessel vasculitis, of unknown etiology, typically presenting in children younger than 5 years of age. Prolonged fever (at least five days) is a major clinical criterion of KD, while cardiac involvement may ...
Wenyan Jiao   +7 more
doaj   +1 more source

Kawasaki Disease

open access: yesActa Paediatrica, 1991
SummaryIn this review, I have outlined the clinical picture, epidemiology, pathology, etiology, and current treatment and management of Kawasaki disease. The disease in question has unique features which cannot be classified into any of the categories of conventional pediatric diseases, and thus the elucidation of the etiology and mode of onset may ...
openaire   +8 more sources

Landscape of intestinal microbiota in patients with IgA nephropathy, IgA vasculitis and Kawasaki disease

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
ObjectiveTo explore the common differential flora of IgAN, Kawasaki disease and IgA vasculitis by screening and analyzing the differential intestinal flora between the three disease groups of IgAN, Kawasaki disease and IgA vasculitis and their healthy ...
Xueli Hu   +10 more
doaj   +1 more source

Hemophagocytosis in the Acute Phase of Fatal Kawasaki Disease in a 4 Month-Old Girl

open access: yesBalkan Medical Journal, 2016
Background: Kawasaki disease is a systemic vasculitis predominately affecting coronary arteries. Hemophagocytic lymphohistiocytosis can complicate the course of Kawasaki disease.
Vehbi Doğan   +4 more
doaj   +1 more source

Kawasaki disease

open access: yesCurrent Opinion in Rheumatology, 1990
Kawasaki disease is an acute vasculitis of young children that is complicated by the development of myocarditis and coronary artery abnormalities. Recent studies indicate that the prevalence of cardiovascular abnormalities can be significantly reduced by treating patients during the first 10 days of illness with high-dose intravenous gammaglobulin ...
R, Sundel, D Y, Leung
openaire   +4 more sources

Activin a suppresses peripheral CD8+ T lymphocyte activity in acute-phase Kawasaki disease

open access: yesBMC Immunology, 2021
Background Kawasaki disease is an autoimmune disease characterized by systemic vasculitis of unknown aetiology and most commonly occurs in children under 5 years old.
Qian Wu   +5 more
doaj   +1 more source

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