Results 91 to 100 of about 8,135 (198)

Advanced DNA–Gold Biointerface for PCR‐Free Molecular Detection of Leishmania infantum

Advanced Materials Interfaces, Volume 12, Issue 5, March 3, 2025.
The development of DNA–gold biointerface is proposed for the Polymerase Chain Reaction (PCR)‐free molecular detection of protozoan Leishmania infantum and the experimental and theoretical investigation of its surface properties, in terms of oligonucleotide probes grafting density and sensing interface isoelectric properties, toward the improvement of ...
Paolo Calorenni, Giovanni Bella, Marco Sebastiano Nicolò, Emanuele Luigi Sciuto, Maria Vittoria Balli, Giovanni Valenti, Tommaso Gritti, Stefania Varani, Luca Prodi, Sabrina Conoci   +9 more
wiley   +1 more source

Schizodeme analysis of Trypanosoma cruzi Colombian strain clones isolated from the acute phase of murine infection

Memorias do Instituto Oswaldo Cruz, 2006
Colombian strain of Trypanosoma cruzi, biodeme Type III (T. cruzi I), has been cloned by micromanipulation at two phases of the acute infection: early (10 days ) and advanced (30 days). Twelve clones were obtained therefrom.
Edson LP Camandaroba, Eliana AG Reis, Mitermayer G Reis, Sonia G Andrade   +3 more
doaj   +1 more source

Molecular variation in Leishmania parasites from sandflies species of a zoonotic cutaneous leishmaniasis in northeast of Iran [PDF]

, 2014
Background & objectives: In the well-known zoonotic cutaneous leishmaniasis (ZCL) focus in Turkmen Sahara, border of Iran and Turkmenistan, ZCL has increased among humans in the past five years.
Parvizi, P., Roshanghalb, M., Sharbatkhori, M., Spotin, A., Taherkhani, H.   +4 more
core  

Cutaneous Leishmaniasis in Khyber Pakhtunkhwa Province of Pakistan: Clinical Diversity and Species-Level Diagnosis. [PDF]

, 2016
This study primarily aimed to identify the causative species of cutaneous leishmaniasis (CL) in the Khyber Pakhtunkhwa Province of Pakistan and to distinguish any species-specific variation in clinical manifestation of CL.
Bari, Arfan Ul, Hashim, Rizwan, Khan, Inamullah, Khan, Nazma Habib, Muneer, Akhtar, O'Neil, Brighid, Shah, Akram, Sutherland, Colin J, Wahid, Sobia, Yardley, Vanessa   +9 more
core   +1 more source

Detection of Visceral Leishmaniasis by Leishmania infantum using kDNA

Al-Kufa University Journal for Biology
Visceral Leishmaniasis is considered one of the endemic parasitic diseases transferred via sand fly Phlebotomus alexandri bite that can be transferred Leishmania infantum. This study aimed to detect visceral leishmaniasis in peripheral blood for patients using IFA test and kDNA polymerase chain reaction.
Zeina Aldahan, Amani Mohammed Jasim, Ghanim Husien Majeed   +2 more
openaire   +1 more source

Novel Naphthyridones Targeting Pannexin 1 for Colitis Management

Advanced Science, Volume 12, Issue 7, February 17, 2025.
This study employs a hit‐to‐lead optimization strategy and identifies a new Pannexin 1 inhibitor with markedly improved specificity and potency than the traditional inhibitors. It also delineates the mechanisms of action and structure–activity relationships of the new compound and highlights this new Pannexin 1 inhibitor as a proof‐of‐concept strategy ...
Wen‐Yun Hsueh, Yi‐Ling Wu, Meng‐Tzu Weng, Shin‐Yun Liu, Jascinta P Santavanond, Yi‐Chung Liu, Ching‐I Lin, Cheng‐Nong Lai, Yi‐Ru Lu, Jing Yin Hsu, Hong‐Yu Gao, Jinq‐Chyi Lee, Shu‐Chen Wei, Ping‐Chiang Lyu, Ivan K H Poon, Hsing‐Pang Hsieh, Yu‐Hsin Chiu   +16 more
wiley   +1 more source

Leishmania infection in cats and dogs housed together in an animal shelter reveals a higher parasite load in infected dogs despite a greater seroprevalence among cats

Parasites & Vectors, 2020
Background An outbreak of leishmaniosis was studied in cats and dogs housed together with no separation in an animal shelter in Israel. Methods The study included recording of clinical signs, serology for Leishmania infection by ELISA, PCR of blood for ...
Gad Baneth, Yaarit Nachum-Biala, Adam Zuberi, Nirit Zipori-Barki, Laor Orshan, Gabriela Kleinerman, Ayelet Shmueli-Goldin, Michel Bellaiche, Monica Leszkowicz-Mazuz, Harold Salant, Daniel Yasur-Landau   +10 more
doaj   +1 more source

Characterization of Allobodo yubaba sp. nov. and Novijibodo darinka gen. et sp. nov., cultivable free‐living species of the phylogenetically enigmatic kinetoplastid taxon Allobodonidae

Journal of Eukaryotic Microbiology, Volume 72, Issue 1, January/February 2025.
Abstract Kinetoplastids are a large and diverse protist group, spanning ecologically important free‐living forms to medically important parasites. The taxon Allobodonidae holds an unresolved position within kinetoplastids, and the sole described species, Allobodo chlorophagus, is uncultivated, being a necrotroph/parasite of macroalgae. Here we describe
Julia A. Packer, Daryna Zavadska, Elizabeth J. Weston, Yana Eglit, Daniel J. Richter, Alastair G. B. Simpson   +5 more
wiley   +1 more source

Evidence of hybridization, mitochondrial introgression and biparental inheritance of the kDNA minicircles in Trypanosoma cruzi I

PLOS Neglected Tropical Diseases, 2019
AbstractBackgroundGenetic Exchange in Trypanosoma cruzi is controversial not only in relation to its frequency but also in relation to its mechanism. A mechanism of parasexuality has been proposed based on laboratory hybrids, but population genomics strongly suggests meiosis.
Fanny Rusman, Noelia Floridia-Yapur, Paula G. Ragone, Patricio Diosque, Nicolás Tomasini   +4 more
openaire   +4 more sources

Advancing Insights Into Visceral Leishmaniasis: Challenges, Innovations, and Future Directions in Global Disease Management

Journal of Parasitology Research, Volume 2025, Issue 1, 2025.
Background Visceral leishmaniasis (VL), also known as kala‐azar, is a life‐threatening neglected tropical disease primarily caused by Leishmania donovani and transmitted by infected sandflies. Despite notable advancements in public health, VL continues to pose significant challenges, especially in South Asia, East Africa, and South America.
Ebrahim Abbasi, Sarita Kumar
wiley   +1 more source