, 2019 In this review, we summarize the current knowledge concerning the eukaryotic protozoan parasite Leishmania tarentolae, with a main focus on its potential for biotechnological applications.
Klatt, S. +3 more
core +1 more source
Hitchhiking Trypanosoma cruzi minicircle DNA affects gene expression in human host cells via LINE-1 retrotransposon [PDF]
, 2006 The horizontal transfer of Trypanosoma cruzi mitochondrial minicircle DNA to the genomes of naturally infected humans may play an important role in the pathogenesis of Chagas disease.
Alves, Nivaldo Pereira +10 more
core +3 more sources
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Effects of PEPCK deficiency in Trypanosoma cruzi bioenergetics and life stages. ABSTRACT Trypanosoma cruzi, the causative agent of Chagas disease, possesses glycosomes—unique organelles that house key metabolic enzymes, several of which are promising therapeutic targets.
Carolina S. D. Vieira +8 more
wiley +1 more source
Journal of Tropical Medicine, 2017 A kDNA PCR enzyme-linked immunosorbent assay (kDNA PCR-ELISA) for the diagnosis of human visceral leishmaniasis (HVL) was developed. The detection limit of the reaction, precision measurements, and cut-off of the kDNA PCR-ELISA were defined in a proof-of-
Fernanda Alvarenga Cardoso Medeiros +8 more
doaj +1 more source
WIREs RNA, Volume 17, Issue 2, March/April 2026.U‐indel RNA editing targets mRNA:gRNA duplexes through three key complexes that collectively govern assembly, specificity, catalysis, and developmental regulation. Modern tools, including artificial intelligence, analyze the organization, dynamics, and evolution of the remarkable holo‐editosome, opening new avenues in RNA biology and therapy.
Suzanne M. McDermott +18 more
wiley +1 more source
Development of a rapid loop-mediated isothermal amplification assay for diagnosis and assessment of cure of Leishmania infection [PDF]
, 2017 BACKGROUND: Leishmaniasis is a spectrum of diseases with great relevance to public health. Conventional diagnostic methods are time consuming, needing trained personnel.
Narendra Singh Negi +6 more
core +1 more source
Evolution and pathology in Chagas disease: a review
Memorias do Instituto Oswaldo Cruz, 2006 Trypanosoma cruzi acute infections often go unperceived, but one third of chronically infected individuals die of Chagas disease, showing diverse manifestations affecting the heart, intestines, and nervous systems.
Antonio RL Teixeira +2 more
doaj +1 more source
And We cast upon his throne a mere body: A Historiographical Reading of Q. 38:34 [PDF]
, 2004 This paper focuses on Q. 38:34 from the perspective of early and medieval works of Islamic historiography and collections of tales of the prophets: the early tenth century works of 'Umara b.
Awn Satan's Tragedy +10 more
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Evaluation of a kDNA-Based qPCR Assay for the Detection and Quantification of Old World Leishmania Species [PDF]
Microorganisms, 2020 The parasite protozoan Leishmania, the causative agent of leishmaniasis, includes two subgenera of medical interest: Leishmania (Leishmania) and Leishmania (Viannia). Parasite species detection and characterization is crucial to choose treatment protocols and to monitor the disease evolution.
Marcello Ceccarelli +9 more
openaire +4 more sources
Clinical use of polymerase chain reaction performed on peripheral blood and bone marrow samples for the diagnosis and monitoring of visceral leishmaniasis in HIV-infected and HIV-uninfected patients: a single-center, 8-year experience in Italy and review of the literature [PDF]
, 2007 Background. To overcome some of the limitations of conventional microbiologic techniques, polymerase chain reaction (PCR)–based assays are proposed as useful tools for the diagnosis of visceral leishmaniasis. Patients and methods.
ACQUAVIVA, V +15 more
core +1 more source