Results 81 to 90 of about 8,135 (198)

Parasitemia Levels in Trypanosoma cruzi Infection in Spain, an Area Where the Disease Is Not Endemic: Trends by Different Molecular Approaches

Microbiology Spectrum, 2022
Trypanosoma cruzi infection has expanded globally through human migration. In Spain, the mother-to-child route is the mode of transmission contributing to autochthonous Chagas disease (CD); however, most people acquired the infection in their country of ...
Maria D. Flores-Chavez, Alba Abras, Cristina Ballart, Ismael Ibáñez-Perez, Pilar Perez-Gordillo, Montserrat Gállego, Carmen Muñoz, Zaira Moure, Elena Sulleiro, Javier Nieto, Emilia García Diez, Lorena Simón, Israel Cruz, Albert Picado   +13 more
doaj   +1 more source

Leishmania infection and host-blood feeding preferences of phlebotomine sandflies and canine leishmaniasis in an endemic European area, the Algarve Region in Portugal [PDF]

, 2013
The Algarve Region (AR) in southern Portugal, which is an international tourist destination, has been considered an endemic region of zoonotic leishmaniasis caused by Leishmania infantum since the 1980s.
Afonso, Maria Odete, Campino, Lenea, Cristovao, Jose Manuel, Dionisio, Lidia, Maia, Carla, Neto, Luis   +5 more
core   +3 more sources

Chemical and mineralogical characteristics of tropical soils on the transport of Na+, K+, Ca2+, and Mg2+ from the application of treated wastewater

Journal of Environmental Quality, Volume 54, Issue 6, Page 1930-1943, November/December 2025.
Abstract With the search for water security, the reuse of water in irrigation becomes interesting and inevitable. Given the complexity of soil–solute interactions, the use of simplified artificial solutions represents an innovative approach, as it facilitates understanding these interactions while posing no risk to human health or the environment ...
Marina N. Merlo, Michael S. Thebaldi, Miguel A. C. Alvarez, Daniela C. de Jesus, Jaqueline dos S. Soares, Elvis M. de C. Lima, Mateus A. da Silva, Luiz A. Lima, Luiz F. C. de Oliveira   +8 more
wiley   +1 more source

Analysis of Kinetoplast DNA from Mexican Isolates of Leishmania (L.) mexicana

Interdisciplinary Perspectives on Infectious Diseases, 2012
This study analyzed DNA minicircles of Mexican isolates of L. (Leishmania) mexicana to look for genetic differences between strains isolated from patients with diffuse cutaneous (DCL) and localized (LCL) leishmaniasis.
Omar Hernández-Montes, Saúl González Guzmán, Federico Martínez Gómez, Douglas C. Barker, Amalia Monroy-Ostria   +4 more
doaj   +1 more source

In Situ Evaluation of Macrophage Populations and Inflammasome Components in Cutaneous and Mucocutaneous Leishmaniasis

Parasite Immunology, Volume 47, Issue 9, September 2025.
ABSTRACT American tegumentary leishmaniasis (ATL) affects the skin and mucous membranes, with a spectrum shaped by Th1/Th2 responses. This study investigated inflammasome activation in correlation with macrophage subpopulations, tissue parasitism, and histological changes in cutaneous and mucocutaneous leishmaniasis. We assessed inflammasome activation,
Caroline de Heleno Chagas de Carvalho, Gabriela Venicia Araujo Flores, Carmen Maria Sandoval Pacheco, Vania Lucia da Ribeiro da Matta, Carolina de Esteves de Morais, Ricardo Romiti, Walter Belda Júnior, Márcia Dalastra Laurenti   +7 more
wiley   +1 more source

Molecular detection and characterization of Leishmania infantum in free-ranging Egyptian mongoose (Herpestes ichneumon)

International Journal for Parasitology: Parasites and Wildlife, 2020
Wild mammals are susceptible to infection by Leishmania parasites. Although canine leishmaniasis is widely distributed in mainland Portugal, the sylvatic cycle of the parasite remains poorly understood. In this study, the occurrence of L.
Jacinto Gomes, Hugo Rocha, Carina Carvalho, Victor Bandeira, Carlos Fonseca, Luís Miguel Rosalino, Mónica V. Cunha   +6 more
doaj   +1 more source

Cryptic infection in Italian HIV infected patients [PDF]

, 2009
Background Visceral leishmaniasis (VL) is a protozoan diseases caused in Europe by Leishmania (L.) infantum. Asymptomatic Leishmania infection is more frequent than clinically apparent disease.
Claudia Colomba, Laura Saporito, Fabrizio Vitale, Stefano Reale, Giustina Vitale, Alessandra Casuccio, Manlio Tolomeo, Daniela Maranto, Raffaella Rubino, Paola Di Carlo, Lucina Titone, P Desjeux, P Desjeux, K Kallel, JA García-García, S Antinori, M Motazedian, R Fisa, A Cascio, World Health Organization, S Mansueto, RG Titus, EJ Tobie, L Manna, World Health Organization Europe, C Mary, CH Costa, F Scarlata, C Colomba, S Bossolasco   +29 more
core   +2 more sources

IL‐12 and IFN‐γ in Response to Leishmania Infantum Antigens in Felines From an Endemic Area for Visceral Leishmaniasis

Parasite Immunology, Volume 47, Issue 8, August 2025.
ABSTRACT Visceral leishmaniasis is a potentially fatal zoonosis with an increasing incidence. Most infected felines present the disease in its subclinical form and demonstrate greater resistance to parasitemia than dogs. However, the role of cellular immunity in felines is still poorly understood. This study measured serum levels of interleukin (IL)‐12
João Victor Lé Lode, Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Valéria Marçal Felix de Lima   +3 more
wiley   +1 more source

Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue [PDF]

, 2009
: BACKGROUND: Topoisomerase II poisons are in clinical use as anti-cancer therapy for decades and work by stabilizing the enzyme-induced DNA breaks. In contrast, catalytic inhibitors block the enzyme before DNA scission.
Patrick Chène, Joëlle Rudloff, Joseph Schoepfer, Pascal Furet, Peter Meier, Zhiyan Qian, Jean-Marc Schlaeppi, Rita Schmitz, Thomas Radimerski, Chène, Patrick   +9 more
core   +1 more source

Leishmania actin binds and nicks kDNA as well as inhibits decatenation activity of type II topoisomerase [PDF]

Nucleic Acids Research, 2010
Leishmania actin (LdACT) is an unconventional form of eukaryotic actin in that it markedly differs from other actins in terms of its filament forming as well as toxin and DNase-1-binding properties. Besides being present in the cytoplasm, cortical regions, flagellum and nucleus, it is also present in the kinetoplast where it appears to associate with ...
Kapoor, Prabodh, Kumar, Ashutosh, Naik, Rangeetha, Ganguli, Munia, Siddiqi, Mohammad I., Sahasrabuddhe, Amogh A., Gupta, Chhitar M.   +6 more
openaire   +2 more sources