Veterinary and Comparative Oncology, EarlyView.ABSTRACT Osteosarcoma (OSA) is a primary bone tumour occurring in children but is also prevalent in large breed dogs. Canine OSA (cOSA) has long been viewed as analogous to human OSA (hOSA) with cOSA serving as a surrogate for development of therapeutic approaches to treat the rarer human form.
Daniel L. Gustafson +5 more
wiley +1 more source
Repellent, irritant and toxic effects of plant EO compounds on the malaria vector Anopheles gambiae ss Giles [PDF]
, 2013 yrethroids resistance has become widespread among malaria vector Anopheles gambiae populations in Africa. Alternative insecticides must be considered to prevent diseases transmission by An. gambiae bites. The long lasted treated bed nets are particularly
Dumenil, Claire
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The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelial cells. [PDF]
, 1993 Arja Kaipainen +6 more
openalex +1 more source
RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling
Glia, Volume 74, Issue 6, June 2026.Using pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Vito Antonio Baldassarro +4 more
wiley +1 more source
\ud Detection and Monitoring of Insecticide Resistance in Malaria Vectors in Tanzania Mainland\ud [PDF]
, 2011 \ud Vector control is a major component of the global strategy for malaria control which aims to prevent parasite transmission mainly through interventions targeting adult Anopheline vectors.
Batengana , B +13 more
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Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells
International Journal of Cancer, Volume 158, Issue 10, Page 2641-2649, 15 May 2026.What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange +9 more
wiley +1 more source
PCR-based methods for the detection of L1014 kdr mutation in Anopheles culicifacies sensu lato [PDF]
, 2009 O. P. Singh +5 more
openalex +1 more source
Presence of kdr and s-kdr resistance in Musca domestica populations collected in Piacenza province (Northern Italy) [PDF]
, 2015 Pyrethroid insecticides combine a high efficacy against insects with a low toxicity towards warm-blooded vertebrates. For this reason they are largely used to control housefly infestations. The efficacy of these products is affected by insecticide resistance mechanisms. In particular, some mutations in the sodium channel coding sequence are responsible
Mazzoni, Emanuele +5 more
openaire +1 more source
Kontrolle heterogener Katalyse mittels Unter‐Oberflächen‐Sauerstoff
Angewandte Chemie, Volume 138, Issue 19, 4 May 2026.Während der CO‐Oxidation auf Rhodiumoberflächen wird die Reaktionsdynamik in der Gegenwart von Unter‐Oberflächen‐Sauerstoff (Osub) deutlich verändert. Unter‐Oberflächen‐Sauerstoff stabilisiert vorübergehend durch Oberflächenreaktionen gebildetes physisorbiertes CO2, was diesem ermöglicht, vorübergehend zu binden und mit der Oberfläche zu thermalisieren.
Arved C. Dorst +6 more
wiley +1 more source