Results 101 to 110 of about 23,687 (206)

RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling

Glia, Volume 74, Issue 6, June 2026.
Using pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Vito Antonio Baldassarro, Quentin Brassart, Valérie Fraulob, Laura Calzà, Wojciech Krezel   +4 more
wiley   +1 more source

Comprehensive Integrated Single‐Cell and Spatial Transcriptomics Unveil the Dynamic Landscape of Betel Nut‐Associated Oral Mucosal Carcinogenesis and Its Tumor Microenvironment

MedComm, Volume 7, Issue 6, June 2026.
ABSTRACT Betel nut chewing is a major etiological factor for oral squamous cell carcinoma (OSCC), yet its mechanistic underpinnings remain poorly defined. Here, we performed single‐cell RNA sequencing and spatial transcriptomics from six OSCC patients to comprehensively dissect the tumor microenvironment (TME) dynamics and cellular heterogeneity ...
Wei Dong, Shuojin Huang, Yijun Wu, Congyuan Cao, Jiaxue Li, Qianting He, Anxun Wang   +6 more
wiley   +1 more source

Pyrethroid Resistance in Frankliniella intonsa From Inner Mongolia: Evidence for kdr Mutation and Metabolic Involvement

Entomological Research, Volume 56, Issue 6, June 2026.
ABSTRACT To evaluate population‐specific susceptibility to pyrethroid insecticides, four field populations of Frankliniella intonsa collected from alfalfa fields in Inner Mongolia were assessed using ingestion and contact bioassays. Four pyrethroids—bifenthrin, cyfluthrin, cypermethrin, and deltamethrin—were tested.
Yue Gao, Yu Miao, Ge Er An, Nan Wu, Si Hyeock Lee, Kyungjae Andrew Yoon, Wen Xue Bao   +6 more
wiley   +1 more source

KDR Positive [PDF]

, 2020
openaire   +1 more source

Epidemiology of Four Major Canine Tumours in the UK: Insights From a National Pathology Registry With Comparative Oncology Perspectives

Veterinary and Comparative Oncology, Volume 24, Issue 2, Page 324-340, June 2026.
ABSTRACT Pet dogs with naturally occurring cancers provide valuable models for comparative oncology and pathology tumour registries offer a powerful resource for onco‐epidemiological research. Here, we analysed the Small Animal Veterinary Surveillance Network (SAVSNET) pathology‐based tumour registry (PTR), one of the largest veterinary tumour ...
José Rodríguez, Antonio Espinosa de los Monteros, Ángelo Santana, P. J. Noble, Alan D. Radford, Francesco Cian, Annika Herrmann, Jenny S. McKay, Matthew Jones, David R. Killick   +9 more
wiley   +1 more source

The southern house mosquito Culex quinquefasciatus in Abu Dhabi, UAE, is developing resistance to deltamethrin insecticide

Scientific Reports
Culex quinquefasciatus is a widely spread mosquito species that poses a significant public health threat in many countries. This insect vector is present in the United Arab Emirates (UAE), yet no studies have been conducted on its resistance to any ...
Amgd sayed Ali, Asim Iqbal, Tamilarasan Kamalanathan, Antony Raj Gnanaprakasam, Sabu Shajahan, Mohammad Hamad Alsadeq, Mohamed Mahmood Al Marzooqi, Mohamad Hamdan, Mohammad Ali Al-Deeb   +8 more
doaj   +1 more source

KDR Gene [PDF]

, 2020
openaire   +1 more source

Erg currents support electrical bursting in murine anterior pituitary corticotrophs

The Journal of Physiology, Volume 604, Issue 12, Page 4834-4850, 15 June 2026.
Abstract figure legend Anterior pituitary corticotrophs are a central component of the hypothalamic‐pituitary‐adrenal (HPA) axis that controls the release of glucocorticoids from the adrenal gland in response to stress. The hypothalamic secretagogue corticotrophin releasing hormone (CRH) promotes electrical bursting of mouse anterior pituitary ...
Sooraj V. Nair, Nicola Romanò, Peter J. Duncan, Paul Le Tissier, Richard Bertram, Michael J. Shipston   +5 more
wiley   +1 more source

Polymorphism of angiogenesis regulation factor genes (VEGF/VEGFR), and extracellular matrix remodeling genes (MMP/TIMP), and the levels of their products in extracellular tissues of patients with primary and secondary lymphedema

Вавиловский журнал генетики и селекции
Cells of various organs and systems perform their functions and intercellular interactions not in an inert environment, but in the microenvironment of tissue fluids. Violations of the normal drainage of tissue fluids accompany lymphedema.
V. I. Konenkov, V. V. Nimaev, A. V. Shevchenko, V. F. Prokofiev   +3 more
doaj   +1 more source

kdr mutations and deltamethrin resistance in house flies in Abu Dhabi, UAE

Parasites & Vectors
Background The house fly, Musca domestica, is a significant carrier of diseases that can impact public health. Repeated use of pyrethroid insecticides may act as a selection pressure for mutations and amino acid substitutions in the house fly voltage ...
Mohamad Hamdan, Tamilarasan Kamalanathan, Asim Iqbal, Antony Raj Gnanaprakasam, Sabu Shajahan, Mohammad Hamad Alsadeq, Amgd sayed Ali, Mohammad Ali Al-Deeb   +7 more
doaj   +1 more source