Results 241 to 250 of about 32,637 (272)

Genomic insights into the spread and evolution of insecticide resistance in Anopheles gambiae s.l. from Burkina Faso

Kientega M, Kaboré H, Sawadogo G, Hui TJ, Traoré N, Millogo A, Maiga H, Miles A, Clarkson CS, Diabaté A.   +9 more
europepmc   +1 more source

Ecological diversity of Anopheles gambiae s.l. and insecticide resistance across refugee camps in Kenya

Rono MK, Wanjiku C, Bartilol B, Oronda A, Nduni A, Kenga G, Tuwei M, Ochola-Oyier LI, Snow RW, Mwangangi J, Maia M.   +10 more
europepmc   +1 more source

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Pyrethroid Resistance and Fitness Cost Conferred by the super-kdr Mutation M918L in Rhopalosiphum padi (Hemiptera: Aphididae)

Journal of Economic Entomology, 2021
Pyrethroid insecticides have been widely utilized for insect pest control. Target-site resistance is one of the major mechanisms explaining pest resistance to pyrethroids.

semanticscholar   +1 more source

Super-kdr mutation M918L and multiple cytochrome P450s associated with the resistance of Rhopalosiphum padi to pyrethroid.

Pest Management Science, 2020
BACKGROUND Rhopalosiphum padi is an important pest affecting cereal crops worldwide. Pyrethroid, including lambda-cyhalothrin, has been widely used to control R. padi in the field. The present work investigated the resistance levels of R.
K. Wang, Jiaoyang Bai, Jun Zhao, Sha Su, Lang Liu, Zhaojun Han, Maohua Chen   +6 more
semanticscholar   +1 more source

The double-mutation（M918I + L1014F）kdr allele is fixed in Cimex hemipterus populations in Guangxi, China

Bulletin of entomological research, 2020
Four putative knockdown resistance (kdr) mutations have been documented in the voltage-gated sodium channel (VGSC) gene of Cimex hemipterus from several countries. However, no information regarding kdr mutations in any Chinese tropical bed bug population
Yu-Han Zhao, Xiangyang Feng, Mei Li, X. Qiu   +3 more
semanticscholar   +1 more source

All resistance alleles are not equal: The high fitness cost of super-kdr in the absence of insecticide.

Pest Management Science, 2020
BACKGROUND Mutations in the voltage-sensitive sodium channel are an important mechanism of resistance to pyrethroid insecticides. In Musca domestica, common resistance alleles are kdr, super-kdr and kdr-his.
J. Freeman, Keri San Miguel, J. G. Scott
semanticscholar   +1 more source

Property-Based Design of KDR Kinase Inhibitors

Current Medicinal Chemistry, 2004
Small molecule inhibitors of KDR kinase activity have typically possessed poor intrinsic physical properties including low aqueous solubility and high lipophilicity. These features have often conferred limited cell permeability manifested in low levels of cell-based KDR inhibitory activity and oral bioavailability.
Mark E, Fraley, William F, Hoffman, Kenneth L, Arrington, Randy W, Hungate, George D, Hartman, Rosemary C, McFall, Kathleen E, Coll, Keith, Rickert, Kenneth A, Thomas, Georgia B, McGaughey   +9 more
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Overcoming super-knock down resistance (super-kdr) mediated resistance: multi-halogenated benzyl pyrethroids are more toxic to super-kdr than kdr house flies.

Insect molecular biology, 2016
Target site insensitivity because of mutations in the voltage-sensitive sodium channel gene (Vssc) is a major mechanism of resistance to pyrethroid insecticides in the house fly, Musca domestica. There are three known Vssc alleles that confer resistance to pyrethroids in the house fly: knock down resistance (kdr; L1014F), super-kdr (M918T + L1014F) and
H, Sun, K P, Tong, S, Kasai, J G, Scott
openaire   +2 more sources

Frequency of kdr Gene in House Fly Field Populations: Correlation of Pyrethroid Resistance and kdr Frequency

Journal of Economic Entomology, 2004
The frequency of the L1014 F kdr mutation was determined in 14 field populations of house flies, Musca domestica L., with resistance factors at LD50 for pyrethrin/piperonyl butoxide and bioresmethrin/piperonyl butoxide from 4 to 29 and 2 to 98, respectively. A polymerase chain reaction test for identifying kdr homo- or heterozygote house flies was used
Huang, J., Kristensen, Michael, Qiao, C.-L., Jespersen, Jørgen Brøchner   +3 more
openaire   +3 more sources

KDR gene polymorphisms and idiopathic recurrent spontaneous abortion

The Journal of Maternal-Fetal & Neonatal Medicine, 2016
Process of angiogenesis is essential for successful gestation. Disruption in this pathway leads to various undesirable consequences in pregnancy such as recurrent spontaneous abortion (RSA). One of the most important genes involved in angiogenesis is kinase-insert domain-containing receptor (KDR).
Negar, Honarvar, Mohammad Hasan, Sheikhha, Ehsan, Farashahi Yazd, Hossein, Pashaiefar, Shirin, Mohtaram, Ali, Sazegari, Zahra, Feizollahi, Nasrin, Ghasemi   +7 more
openaire   +2 more sources