The impact of high density receptor clusters on VEGF signaling [PDF]
Electronic Proceedings in Theoretical Computer Science, 2013 Vascular endothelial growth factor (VEGF) signaling is involved in the process of blood vessel development and maintenance. Signaling is initiated by binding of the bivalent VEGF ligand to the membrane-bound receptors (VEGFR), which in turn stimulates ...
Ye Chen +3 more
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The Role of VEGF Receptors as Molecular Target in Nuclear Medicine for Cancer Diagnosis and Combination Therapy [PDF]
Cancers, 2021 Paweł Halik +2 more
exaly +2 more sources
Compartmentalized VEGF receptor expression in hypothalamic tanycytes reveals a novel non-endothelial axis of VEGF signaling [PDF]
Fluids and Barriers of the CNSBackground Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are critical regulators of angiogenesis and vascular homeostasis. While VEGF signaling has been extensively studied in endothelial cells, emerging evidence suggests it ...
Ombeline Desruelle +7 more
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Comparative in silico Survey of Retinoic Acids as Putative Biomolecules Against VEGF Receptors: A Glycomics-based Approach [PDF]
Journal of Cell and Molecular Research, 2021 In this study, putative interactions between all of the retinoic acid (RA) ligands (all-trans (At), 9-cis (9c), and 13-cis (13c)), and VEGF receptors (VEGFR-1, -2 and -3) were investigated.
Ali Fallah +3 more
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An Investigation of Vascular Endothelial Growth Factor (VEGFR-1 and VEGFR-2) in Burn Wound Healing [PDF]
Archives of Razi Institute, 2022 Burn damage is a complicated trauma that causes local and general tissue edema as a result of cell breakage and capillary leak syndrome. Angiogenesis plays a key part in the mechanisms that are initiated by tissue damage (e.g., burns) since it works ...
L Abdulazeem, A Tariq, Saade Jasim
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Nephrotoxicity induced by vascular endothelial growth factor inhibitors [PDF]
Journal of Nephropharmacology, 2022 Vascular endothelial growth factor (VEGF) is a special mitogen for vascular endothelial cells, an essential endogenous angiogenic cytokine, and the principal controller of vascular growth that plays a fundamental role in therapeutic angiogenesis pathways.
Shirinsadat Badri +5 more
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The presence of VEGF receptors on the luminal surface of endothelial cells affects VEGF distribution and VEGF signaling. [PDF]
PLoS Computational Biology, 2009 Vascular endothelial growth factor (VEGF) is a potent cytokine that binds to specific receptors on the endothelial cells lining blood vessels. The signaling cascade triggered eventually leads to the formation of new capillaries, a process called ...
Marianne O Stefanini +3 more
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Specific dynamics in vascular endothelial growth factors (VEGF) in blood of patients with vitamin D-resistant rickets during correction of multiplanar deformities of lower limbs [PDF]
Гений oртопедии, 2020 Background Vitamin D-resistant rickets is a systemic disease with impaired bone remodeling that interferes with orthopaedic treatment of musculoskeletal pathologies.
Nikita S. Gvozdev +5 more
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Expression of Protease-Activated Receptor 1 and 2 and Anti-Tubulogenic Activity of Protease-Activated Receptor 1 in Human Endothelial Colony-Forming Cells [PDF]
, 2014 Endothelial colony-forming cells (ECFCs) are obtained from the culture of human peripheral blood mononuclear cell (hPBMNC) fractions and are characterised by high proliferative and pro-vasculogenic potential, which makes them of great interest for cell ...
A Kawabata +41 more
core +13 more sources
The immunohistochemical landscape of the VEGF family and its receptors in glioblastomas
Surgical and Experimental Pathology, 2020 Background Angiogenesis is one of the hallmarks of cancer. This complex mechanism of tumor progression provides tumors cells with essential nutrients. There have been a limited number of investigations of markers of angiogenesis in Glioblastomas (GBMs ...
Luiz Victor Maia Loureiro +5 more
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