Results 11 to 20 of about 228,627 (303)
Fox(y) regulators of VEGF receptors. [PDF]
Circ Res, 2014 Vascular development is a multistep process that initially involves vasculogenesis, the process of de novo formation of the primitive vasculature from mesodermal precursors, and angiogenesis, that involves sprouting and remodeling of the primitive vasculature.1 This is followed by vascular fate specification steps that define formation of arterial ...
Ricard N, Simons M.
europepmc +4 more sources
Zebrafish VEGF receptors: a guideline to nomenclature. [PDF]
PLoS Genetics, 2008 In placental mammals (eutherians), there exist three paralogous genes of the vascular endothelial growth factor (VEGF) receptor family, namely FLT1 (also named VEGFR1), KDR (also named FLK1 and VEGFR2), and FLT4 (also named VEGFR3). Recent analysis of the VEGF receptor repertoire in basally diverging vertebrates has identified a fourth representative ...
Jeroen Bussmann +4 more
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VEGF and its receptors - formation, structure, and role in the organism
Journal of Education, Health and Sport, 2023 Creating vessels is essential for the development of every organism and the course of repair processes. Under physiological conditions, angiogenesis is a transient and tightly regulated process.
Krzysztof Olczyk +3 more
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Mechanism of selective VEGF-A binding by neuropilin-1 reveals a basis for specific ligand inhibition. [PDF]
PLoS ONE, 2012 Neuropilin (Nrp) receptors function as essential cell surface receptors for the Vascular Endothelial Growth Factor (VEGF) family of proangiogenic cytokines and the semaphorin 3 (Sema3) family of axon guidance molecules. There are two Nrp homologues, Nrp1
Matthew W Parker +3 more
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Aflibercept—a Decoy VEGF Receptor [PDF]
Current Oncology Reports, 2014 Aflibercept (known as ziv-aflibercept in the USA and sold under the trade name Zaltrap®) is a human recombinant fusion protein with antiangiogenic effects that functions as a decoy receptor to bind vascular endothelial growth factors A and B and placental growth factor.
Kristen K, Ciombor, Jordan, Berlin
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Cellular Physiology and Biochemistry, 2017 Background: Neuropathic pain is a type of chronic pain that results from dysfunctions of the somatosensory nerve system. This study was aimed to investigate the effect of mTOR/VEGF signaling pathway on neuropathic pain and the regulation mechanisms of ...
Xiaojuan Xie +4 more
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Journal of Translational Medicine, 2022 Background An imbalance in the expression of vascular endothelial growth factor (VEGF) and its receptor (VEGF-R) during pregnancy plays an important role in the pathogenesis of gestational diabetes mellitus (GDM) and eclampsia.
Alayi Bolatai, Yujing He, Na Wu
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Brain homeostasis : VEGF receptor 1 and 2 ; two unequal brothers in mind [PDF]
, 2013 Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the vascular system, exert trophic effects on neural cells during development and adulthood.
Plate, Karl H. +2 more
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The Role of Rho GTPases in VEGF Signaling in Cancer Cells
Analytical Cellular Pathology, 2020 Vascular endothelial growth factors (VEGFs) consist of five molecules (VEGFA through D as well as placental growth factor) which are crucial for regulating key cellular and tissue functions. The role of VEGF and its intracellular signaling and downstream
Nada El Baba +5 more
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Veterinary Sciences, 2022 Cutaneous squamous cell carcinoma (CSCC) is a common malignant skin cancer with a significant impact on health, and it is important to determine the degree of reliance of CSCC on angiogenesis for growth and metastasis.
Erwin Kristobal Gudenschwager-Basso +4 more
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