Dynamic soluble changes in sVEGFR1, HGF, and VEGF promote chemotherapy and bevacizumab resistance: A prospective translational study in the BECOX (GEMCAD 09-01) trial [PDF]
Despite initial responsiveness, acquired resistance to both bevacizumab and chemotherapy in metastatic colorectal cancer is universal. We have recently published that in vitro, chronically oxaliplatin resistance upregulates soluble vascular endothelial ...
Estela Pineda +19 more
doaj +3 more sources
Evaluation of the vascular remodeling markers elastin, vascular endothelial growth factor A (VEGF-A), vascular endothelial growth factor receptor 2 (VEGFR2), and nitric oxide in patients with varicose veins [PDF]
Sarah H. Shaalan, Furqan Moein Auda
doaj +2 more sources
Encapsulated VEGF121-PLA microparticles promote angiogenesis in human endometrium stromal cells
Background In this study, Vascular Endothelial Growth Factor 121 expressed abundantly in endometrial stromal cells is encapsulated with poly-l-lactide and characterized the properties for endometrial angiogenesis.
Sunil Abraham +3 more
doaj +1 more source
Background Intravitreal injections of anti-vascular endothelial growth factor are commonly used to treat macular diseases, including diabetic macular edema.
Miwako Yoshimoto +3 more
doaj +1 more source
Purpose of the study. Based on the assessment of endothelial and hemostasiological parameters, to study the possibilities of early diagnosis of vascular disorders in case of vibration disease in combination with arterial hypertension.
Oksana N. Gerasimenko +4 more
doaj +1 more source
Vascular Endothelial Growth Factor [PDF]
Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. Several VEGF inhibitors have been approved by the FDA for the treatment of advanced cancer and neovascular age-related macular degeneration.
openaire +4 more sources
Streptozotocin induced diabetic retinopathy in rat and the expression of vascular endothelial growth factor and its receptor [PDF]
AIM:To establish the rat model of streptozotocin (STZ)-induced diabetic retinopathy (DR), which is the most common cause of visual loss and blindness in patients with diabetes, and observe the gene expression of vascular endothelial growth factor (VEGF ...
Chen-Yuan Gong +3 more
doaj +1 more source
Vascular endothelial growth factor receptor-1 mRNA overexpression in peripheral blood as a useful prognostic marker in breast cancer [PDF]
INTRODUCTION: Identification of useful markers associated with poor prognosis in breast cancer patients is critically needed. We previously showed that expression of vascular endothelial growth factor receptor-1 mRNA in peripheral blood may be useful to ...
Akemi Kataoka +10 more
core +2 more sources
Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats
INTRODUCTION: Cardiovascular disease is one of the main causes of mortality and morbidity in diabetic patients. This study evaluated the effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide ...
Majid Khazaei +5 more
doaj +1 more source
Positive and negative regulation of angiogenesis by soluble vascular endothelial growth factor receptor-1 [PDF]
Vascular endothelial growth factor receptor (VEGFR)-1 exists in different forms, derived from alternative splicing of the same gene. In addition to the transmembrane form, endothelial cells produce a soluble VEGFR-1 (sVEGFR-1) isoform, whereas non ...
Carbo, Miriam +2 more
core +2 more sources

