Results 1 to 10 of about 724,253 (297)

Dynamic soluble changes in sVEGFR1, HGF, and VEGF promote chemotherapy and bevacizumab resistance: A prospective translational study in the BECOX (GEMCAD 09-01) trial [PDF]

open access: yesTumor Biology, 2017
Despite initial responsiveness, acquired resistance to both bevacizumab and chemotherapy in metastatic colorectal cancer is universal. We have recently published that in vitro, chronically oxaliplatin resistance upregulates soluble vascular endothelial ...
Estela Pineda   +19 more
doaj   +3 more sources

Encapsulated VEGF121-PLA microparticles promote angiogenesis in human endometrium stromal cells

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background In this study, Vascular Endothelial Growth Factor 121 expressed abundantly in endometrial stromal cells is encapsulated with poly-l-lactide and characterized the properties for endometrial angiogenesis.
Sunil Abraham   +3 more
doaj   +1 more source

Hypertensive cerebral hemorrhage with undetectable plasma vascular endothelial growth factor levels in a patient receiving intravitreal injection of aflibercept for bilateral diabetic macular edema: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Intravitreal injections of anti-vascular endothelial growth factor are commonly used to treat macular diseases, including diabetic macular edema.
Miwako Yoshimoto   +3 more
doaj   +1 more source

Clinical-functional and molecular characteristics of comorbid pathology (vibration disease combined with arterial hypertension)

open access: yesАтеросклероз, 2022
Purpose of the study. Based on the assessment of endothelial and hemostasiological parameters, to study the possibilities of early diagnosis of vascular disorders in case of vibration disease in combination with arterial hypertension.
Oksana N. Gerasimenko   +4 more
doaj   +1 more source

Vascular Endothelial Growth Factor [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 1993
Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. Several VEGF inhibitors have been approved by the FDA for the treatment of advanced cancer and neovascular age-related macular degeneration.
openaire   +4 more sources

Streptozotocin induced diabetic retinopathy in rat and the expression of vascular endothelial growth factor and its receptor [PDF]

open access: yesInternational Journal of Ophthalmology, 2013
AIM:To establish the rat model of streptozotocin (STZ)-induced diabetic retinopathy (DR), which is the most common cause of visual loss and blindness in patients with diabetes, and observe the gene expression of vascular endothelial growth factor (VEGF ...
Chen-Yuan Gong   +3 more
doaj   +1 more source

Vascular endothelial growth factor receptor-1 mRNA overexpression in peripheral blood as a useful prognostic marker in breast cancer [PDF]

open access: yes, 2012
INTRODUCTION: Identification of useful markers associated with poor prognosis in breast cancer patients is critically needed. We previously showed that expression of vascular endothelial growth factor receptor-1 mRNA in peripheral blood may be useful to ...
Akemi Kataoka   +10 more
core   +2 more sources

Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats

open access: yesClinics, 2011
INTRODUCTION: Cardiovascular disease is one of the main causes of mortality and morbidity in diabetic patients. This study evaluated the effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide ...
Majid Khazaei   +5 more
doaj   +1 more source

Positive and negative regulation of angiogenesis by soluble vascular endothelial growth factor receptor-1 [PDF]

open access: yes, 2018
Vascular endothelial growth factor receptor (VEGFR)-1 exists in different forms, derived from alternative splicing of the same gene. In addition to the transmembrane form, endothelial cells produce a soluble VEGFR-1 (sVEGFR-1) isoform, whereas non ...
Carbo, Miriam   +2 more
core   +2 more sources

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