Results 11 to 20 of about 92,357 (302)

Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]

, 2001
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Losa, Marco, Lohrer, P., Gloddek, J., Renner, U., Lohrer, Penny, Uhl, E., Stalla, G., Pagotto, U., Hopfner, Ursula, Renner, Ulrich, Losa, Marc, Losa, M., Pagotto, Uberto, Gloddek, Jutta, Uhl, Eberhard, Stalla, Günter K., Hopfner, U.   +16 more
core   +1 more source

Clinical-functional and molecular characteristics of comorbid pathology (vibration disease combined with arterial hypertension)

Атеросклероз, 2022
Purpose of the study. Based on the assessment of endothelial and hemostasiological parameters, to study the possibilities of early diagnosis of vascular disorders in case of vibration disease in combination with arterial hypertension.
Oksana N. Gerasimenko, Lyubov A. Shpagina, Alena M. Gorbunova, Ilya S. Shpagin, Yanina S. Sergeeva   +4 more
doaj   +1 more source

Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats

Clinics, 2011
INTRODUCTION: Cardiovascular disease is one of the main causes of mortality and morbidity in diabetic patients. This study evaluated the effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide ...
Majid Khazaei, Ali Reza Fallahzadeh, Mohammad Reza Sharifi, Noushin Afsharmoghaddam, Shaghayegh Haghjooy Javanmard, Ensieh Salehi   +5 more
doaj   +1 more source

Streptozotocin induced diabetic retinopathy in rat and the expression of vascular endothelial growth factor and its receptor [PDF]

International Journal of Ophthalmology, 2013
AIM:To establish the rat model of streptozotocin (STZ)-induced diabetic retinopathy (DR), which is the most common cause of visual loss and blindness in patients with diabetes, and observe the gene expression of vascular endothelial growth factor (VEGF ...
Chen-Yuan Gong, Bin Lu, Qian-Wen Hu, Li-Li Ji   +3 more
doaj   +1 more source

Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature [PDF]

, 2010
Vascular endothelial growth factor (VEGF) plays a critical role in normal development as well as retinal vasculature disease. During retinal vascularization, VEGF is most strongly expressed by not yet vascularized retinal astrocytes, but also by retinal ...
Michael B. Powner, Powner, MB, Scott, A., Clarkin, C., Gandhi, P, Scott, Andrew, David H Gutmann, Randall S Johnson, Fruttiger, Marcus, Gutmann, DH, Johnson, RS, David H. Gutmann, Gutmann David H., Gutmann, David H., Powner Michael B., Gandhi, P., Scott Andrew, Clarkin Claire, Ferrara, N., Gandhi Pranita, Napoleone Ferrara, Johnson Randall S., Clarkin, Claire, Scott, A, Pranita Gandhi, Ferrara, Napoleone, Michael B Powner, Fruttiger Marcus, Gandhi, Pranita, Powner, Michael B., Ferrara Napoleone, Andrew Scott, Powner, M. B., Connon, Che John, Ferrara, N, Claire Clarkin, Clarkin, C, Fruttiger, M., Johnson, R.S., Gutmann, D.H., Fruttiger, M, Randall S. Johnson, Johnson, Randall S., Marcus Fruttiger   +43 more
core   +1 more source

Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages [PDF]

, 2007
Genetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)-induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy.
Pollard, Jeffrey W, Bricard, Gabriel, Wang, Weigang, Deng, Yan, Porcelli, Steven A, Sellers, Rani, Lin, Elaine Y, Li, Jiu-feng   +7 more
core   +1 more source

Vascular endothelial growth factors and vascular permeability [PDF]

Cardiovascular Research, 2010
Vascular endothelial growth factors (VEGFs) are key regulators of permeability. The principal evidence behind how they increase vascular permeability in vivo and in vitro and the consequences of that increase are addressed here. Detailed analysis of the published literature has shown that in vivo and in vitro VEGF-mediated permeability differs in its ...
openaire   +2 more sources

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]

, 2003
Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Shima, D., Christiana Ruhrberg, Betsholtz, C, Jeltsch, M, Abramsson, A., Shima, D, Matthew Golding, Lundkvist, A, Lundkvist, A., Golding, M, David Shima, Ruhrberg, C, Christopher Mitchell, Mitchell, C, Betsholtz, C., Kari Alitalo, Gerhardt, H, Ruhrberg, C., Christer Betsholtz, Golding, M., Jeltsch, M., Holger Gerhardt, Abramsson, A, Alitalo, K, Andrea Lundkvist, Fruttiger, M., Gerhardt, H., Alitalo, K., Alexandra Abramsson, Mitchell, C., Fruttiger, M, Michael Jeltsch, Marcus Fruttiger   +32 more
core   +1 more source

Dynamic soluble changes in sVEGFR1, HGF, and VEGF promote chemotherapy and bevacizumab resistance: A prospective translational study in the BECOX (GEMCAD 09-01) trial

Tumor Biology, 2017
Despite initial responsiveness, acquired resistance to both bevacizumab and chemotherapy in metastatic colorectal cancer is universal. We have recently published that in vitro, chronically oxaliplatin resistance upregulates soluble vascular endothelial ...
Estela Pineda, A Salud, E Vila-Navarro, MJ Safont, Beatriz Llorente, J Aparicio, R Vera, P Escudero, E Casado, C Bosch, U Bohn, R Pérez-Carrión, A Carmona, JR Ayuso, T Ripollés, R Bouzas, M Gironella, X García-Albéniz, J Feliu, J Maurel   +19 more
doaj   +1 more source

Structural and functional characterization of the intracellular kinase domain of vascular endothelial growth factor receptor-2 [PDF]

, 2013
Vascular Endothelial Growth Factors (VEGFs) are key players in blood and lymphatic vessel development and homeostasis. The family consists of five members, VEGF-A, -B, -C, -D and placenta growth factor (PLGF).
Manni, Sandro
core   +1 more source