Results 51 to 60 of about 53,382 (285)

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

Advanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng   +11 more
wiley   +1 more source

Bionomics and insecticide resistance of Aedes albopictus in Shandong, a high latitude and high-risk dengue transmission area in China

Parasites & Vectors, 2020
Background Dengue fever outbreaks tend to spread northward in China, and Jining is the northernmost region where local dengue fever cases have been detected.
Hongmei Liu, Luhong Liu, Peng Cheng, Linlin Yang, Junhu Chen, Yao Lu, Haifang Wang, Xiao-Guang Chen, Maoqing Gong   +8 more
doaj   +1 more source

Physiological evidence that three known mutations in the para-sodium channel gene confer cypermethrin knockdown resistance in Rhipicephalus microplus

Parasites & Vectors, 2020
Background Acaricide resistance is a central problem for the control of the cattle tick Rhipicephalus microplus. The physiological effects and phenotypes of the mutations that cause acaricide resistance are not always well understood or characterized ...
Raquel Cossío-Bayúgar, Estefan Miranda-Miranda, Francisco Martínez-Ibañez, Verónica Narváez-Padilla, Enrique Reynaud   +4 more
doaj   +1 more source

Plasmon Assisted Transparency in Metal--Dielectric Microspheres [PDF]

, 2006
We present a theoretical analysis of light scattering from a layered metal-dielectric microsphere. The system consists of two spherical resonators, coupled through concentric embedding.
Deutsch, Miriam, Hasegawa, Keisuke, Rohde, Charles   +2 more
core   +3 more sources

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Status of insecticide resistance in Anopheles gambiae (s.l.) of The Gambia

Parasites & Vectors, 2019
Background Vector control activities, namely long-lasting insecticidal nets (LLIN) and indoor residual spraying (IRS), have contributed significantly to the decreasing malaria burden observed in The Gambia since 2008. Nevertheless, insecticide resistance
Kevin Ochieng’ Opondo, Musa Jawara, Saihou Cham, Ebrima Jatta, Lamin Jarju, Muhammed Camara, Fatou Sanneh, Pa Modou Gaye, Lamin Jadama, Sainey Ceesay, Ebrima Njie, Benoit Sessinou Assogba, Balla Kandeh, Umberto D’Alessandro   +13 more
doaj   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Phenotypic resistance not associated with knockdown mutations (kdr) in Anopheles albimanus exposed to deltamethrin in southern coastal Ecuador

Malaria Journal
Background Decrease in malaria rates (e.g. incidence and cases) in Latin America maintains this region on track to achieve the goal of elimination. During the last 5 years, three countries have been certified as malaria free. However, the region fails to
Sebasthian Real-Jaramillo, Juan J. Bustillos, Ana L. Moncayo, Marco Neira, Leonardo Fárez, Efraín Beltrán, Sofía Ocaña-Mayorga   +6 more
doaj   +1 more source

Ion‐Pair‐Tuned Ionogels for Broad‐Range Linear Pressure Sensing

Advanced Science, EarlyView.
Ionogels engineered through ion‐pair tuning extend the linear sensing range of capacitive pressure sensors. By balancing ionic mobility and polarizability within the polymer matrix, this approach mitigates dielectric saturation and maintains a stable pressure response across a broad operating range.
Hyeonseo Joo, Tianhao Yu, Yumin Dai, Seokkyoon Hong, Axel González Cornejo, Tristan Michael Long, Sang Mok Park, Pete S. Kollbaum, Edgar Bolívar‐Nieto, Young L. Kim, Dong Rip Kim, Chi Hwan Lee   +11 more
wiley   +1 more source

Knockdown resistance (kdr) mutations in Indian Anopheles culicifacies populations [PDF]

Parasites & Vectors, 2015
Anopheles culicifacies s.l. is one of the primary vectors of malaria in India responsible for the highest number of malaria cases. This vector is resistant to DDT in most parts of the country with indication of emerging resistance to pyrethroids. Since knockdown resistance (kdr) is known to confer cross-resistance between DDT and pyrethroids owing to a
Cherry L. Dykes, Raja Babu S. Kushwah, Manoj K. Das, Shri N. Sharma, Rajendra M. Bhatt, Vijay Veer, Om P. Agrawal, Tridibes Adak, Om P. Singh   +8 more
openaire   +3 more sources