Results 31 to 40 of about 53,382 (285)

Endothelial progenitor cells and burn injury - exploring the relationship. [PDF]

, 2016
Burn wounds result in varying degrees of soft tissue damage that are typically graded clinically. Recently a key participant in neovascularization, the endothelial progenitor cell, has been the subject of intense cardiovascular research to explore ...
Adnani, Blake O, Araniego, Cheryl Ann, Banyard, Derek A, Melkumyan, Satenik, Widgerow, Alan D   +4 more
core   +2 more sources

Malaria vectors in the Democratic Republic of the Congo: the mechanisms that confer insecticide resistance in Anopheles gambiae and Anopheles funestus

Malaria Journal, 2017
Background The Democratic Republic of the Congo (DRC) is characterized as a holoendemic malaria area with the main vectors being Anopheles funestus and members of the Anopheles gambiae complex.
Luisa Nardini, Richard H. Hunt, Yael L. Dahan-Moss, Nanette Christie, Riann N. Christian, Maureen Coetzee, Lizette L. Koekemoer   +6 more
doaj   +1 more source

Implications of bio-efficacy and persistence of insecticides when indoor residual spraying and longlasting insecticide nets are combined for malaria prevention. [PDF]

, 2012
Bio-efficacy and residual activity of insecticides used for indoor residual spraying (IRS) and long-lasting insecticide nets (LLINs) were assessed against laboratory-reared and wild populations of the malaria vector, Anopheles arabiensis in south eastern
Chipwaza, Beatrice, Kavishe, Deo R, Lingamba, Geoffrey, Madumla, Edith P, Mbeyela, Edgar, Moore, Jason, Moore, Sarah J, Ntamatungro, Alex J, Okumu, Fredros O   +8 more
core   +2 more sources

Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types [PDF]

, 2017
In this study we use somatic cancer mutations to identify important functional residues within sets of related genes. We focus on protein kinases, a superfamily of phosphotransferases that share homologous sequences and structural motifs and have many ...
Bose, Ron, Kumar, Runjun D
core   +2 more sources

ECSCR enhances KDR activation and promotes proteolysis of internalized KDR (LB160)

The FASEB Journal, 2014
The endothelial cell‐specific chemotaxis receptor (ECSCR) is a cell‐surface protein selectively expressed by endothelial cells (ECs), with roles in EC migration, apoptosis and proliferation. Our previous study showed that loss of ECSCR in primary ECs reduced tyrosine phosphorylation of vascular endothelial growth factor (VEGF) receptor 2/kinase insert ...
George Wilkinson, Sreenivas Kilari, Indulekha Remadevi, Baofeng Baofeng Zhao, Jing Pan, Robert Miao, Ramani Ramchandran, Paula North, Ming You, Nader Rahimi   +9 more
openaire   +1 more source

Bio-efficacy of selected long-lasting insecticidal nets against pyrethroid resistant Anopheles arabiensis from South-Western Ethiopia. [PDF]

, 2012
The emergence and spread of insecticide resistance in the major African malaria vectors Anopheles gambiae s.s. and Anopheles arabiensis may compromise control initiatives based on insecticide-treated nets (ITNs) or indoor residual spraying (IRS), and ...
Asale, Abebe, Duchateau, Luc, Getachew, Yehenew, Speybroeck, Niko, Tushune, Kora, Yewhalaw, Delenasaw   +5 more
core   +3 more sources

A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. [PDF]

, 2020
BackgroundTumors comprise a complex microenvironment of interacting malignant and stromal cell types. Much of our understanding of the tumor microenvironment comes from in vitro studies isolating the interactions between malignant cells and a single ...
Azizi, Armon, Bejnood, Alborz, Bouchard, Gina, Diehn, Maximilian, Feng, Weiguo, Forgó, Erna, Gentles, Andrew J, Hoang, Chuong D, Hui, Angela Bik-Yu, Jeong, Youngtae, Knowles, David A, Kuong, Amanda, Nair, Ramesh V, Nair, Viswam S, Plevritis, Sylvia K, van de Rijn, Matt, Varma, Sushama, West, Rob, Xu, Yue, Yu, Alice   +19 more
core   +4 more sources

Evolution of kdr haplotypes in worldwide populations of Aedes aegypti: Independent origins of the F1534C kdr mutation

PLOS Neglected Tropical Diseases, 2020
Aedes aegypti is the primary vector of dengue, chikungunya, Zika, and urban yellow fever. Insecticides are often the most effective tools to rapidly decrease the density of vector populations, especially during arbovirus disease outbreaks. However, the intense use of insecticides, particularly pyrethroids, has selected for resistant mosquito ...
Luciano Veiga Cosme, Andrea Gloria-Soria, Adalgisa Caccone, Jeffrey Robert Powell, Ademir Jesus Martins   +4 more
openaire   +3 more sources

A combination of metabolic resistance and high frequency of the 1014F kdr mutation is driving pyrethroid resistance in Anopheles coluzzii population from Guinea savanna of Cameroon

Parasites & Vectors, 2019
Background The scale-up in the distribution of long-lasting insecticidal nets (LLINs) and indoor residual spraying has significantly reduced malaria burden and mortality.
Amen N. Fadel, Sulaiman S. Ibrahim, Magellan Tchouakui, Ebai Terence, Murielle J. Wondji, Micareme Tchoupo, Samuel Wanji, Charles S. Wondji   +7 more
doaj   +1 more source

First report of kdr mutations in the voltage-gated sodium channel gene in the arbovirus vector, Aedes aegypti, from Nouakchott, Mauritania

Parasites & Vectors, 2023
Background Since 2014, dengue epidemics have occurred almost annually in Nouakchott, the capital city of Mauritania, coinciding with the recent establishment of Aedes aegypti, the primary vector of dengue, in the city.
Mohamed Aly Ould Lemrabott, Sébastien Briolant, Nicolas Gomez, Leonardo Basco, Ali Ould Mohamed Salem Boukhary   +4 more
doaj   +1 more source