Results 11 to 20 of about 23,687 (206)

Polyphenol-Rich Duhuo Jisheng Decoction Enhances Mesenchymal Stem Cell-Derived Exosome-Mediated Chondroprotection via PI3K/AKT Signaling in Osteoarthritis. [PDF]

Food Sci Nutr
This graphical abstract illustrates the chondroprotective mechanism of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) preconditioned with polyphenol‐rich Duhuo Jisheng Decoction (DHJST‐Exos). Enriched with bioactive compounds such as wogonin, quercetin, and kaempferol, DHJST‐Exos effectively ameliorate osteoarthritis (OA ...
Liao Z, Wang W, Jiang S, Wang L, Yu T, Ni X, Zhang S, Liu J, Yang J, Xie H.   +9 more
europepmc   +2 more sources

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Isolation of Sponge Bacterial Symbionts from Kodingareng Keke Island-Makassar Indonesia Which is Potential as a Producer of Antimicrobial Compounds

Journal of Pure and Applied Microbiology, 2022
Sponge is an invertebrate animal in the Porifera phylum, which potentially produces bioactive compounds that are known as potential agents in producing antimicrobial compounds.
Herlina Rante, Gemini Alam, Usmar Usmar, Rhezky Awalia Anwar, Alimuddin Ali   +4 more
doaj   +1 more source

A comparison of DNA sequencing and the hydrolysis probe analysis (TaqMan assay) for knockdown resistance (kdr) mutations in Anopheles gambiae from the Republic of the Congo

Malaria Journal, 2010
Background Knockdown resistance (kdr) caused by a single base pair mutation in the sodium channel gene is strongly associated with pyrethroid insecticide resistance in Anopheles gambiae in West-Central Africa.
Coetzee Maureen, Spillings Belinda L, Choi Kwang, Hunt Richard H, Koekemoer Lizette L   +4 more
doaj   +1 more source

Distribution and pyrethroid resistance status of Aedes aegypti and Aedes albopictus populations and possible phylogenetic reasons for the recent invasion of Aedes aegypti in Nepal

Parasites & Vectors, 2020
Background When the first systematic list of mosquitoes in Nepal was reported in 1990, there was no description of Aedes aegypti (L.), while Aedes albopictus (Skuse) has been included in the Stegomyia subgroup since the 1950s.
Hitoshi Kawada, Kyoko Futami, Yukiko Higa, Ganesh Rai, Takashi Suzuki, Shiba Kumar Rai   +5 more
doaj   +1 more source

Integrated Network Pharmacology and Machine Learning to Reveal the Mechanisms of Schisandrin A Against Triple-Negative Breast Cancer. [PDF]

J Cell Mol Med
ABSTRACT This study aimed to elucidate the mechanism of action of Schisandrin A in the intervention of triple‐negative breast cancer (TNBC). Through the application of network pharmacology and the integration of targets from multiple databases, the research identified 128 overlapping targets between Schisandrin A and TNBC.
Xu M, Zhang Y, Mei R, Xue T, Cai H, Zhou Y, Guo J.   +6 more
europepmc   +2 more sources

Molecular identification of allelic genotypes of pyrethroid-insecticide resistance in housefly, Iraq [PDF]

Iraqi Journal of Veterinary Sciences, 2019
According to global-wide presence of insecticides resistance to pyrethroids, the current study identified the purpose to detect the allelic genotypes regarding this issue in house flies in Iraq.
Monyer Abdulameir Abd Alfatlawi, Mansour Ali, Hassan Naser   +2 more
doaj   +1 more source

Assessing the effects of Aedes aegypti kdr mutations on pyrethroid resistance and its fitness cost. [PDF]

PLoS ONE, 2013
Pyrethroids are the most used insecticide class worldwide. They target the voltage gated sodium channel (NaV), inducing the knockdown effect. In Aedes aegypti, the main dengue vector, the AaNaV substitutions Val1016Ile and Phe1534Cys are the most ...
Luiz Paulo Brito, Jutta G B Linss, Tamara N Lima-Camara, Thiago A Belinato, Alexandre A Peixoto, José Bento P Lima, Denise Valle, Ademir J Martins   +7 more
doaj   +1 more source

Molecular analysis of knockdown resistance (kdr) mutations in the voltage-gated sodium channel gene of Aedes aegypti populations from Saudi Arabia

Parasites & Vectors, 2022
Background The Aedes aegypti mosquito is the primary vector for dengue, chikungunya, yellow fever and Zika viruses worldwide. The first record of Ae. aegypti in southwestern Saudi Arabia was in 1956.
Abadi M. Mashlawi, Ashwaq M. Al-Nazawi, Elsiddig M. Noureldin, Hussain Alqahtani, Jazem A. Mahyoub, Jassada Saingamsook, Mustapha Debboun, Martha Kaddumukasa, Hesham M. Al-Mekhlafi, Catherine Walton   +9 more
doaj   +1 more source

Multiplex PCR for simultaneous genotyping of kdr mutations V410L, V1016I and F1534C in Aedes aegypti (L.)

Parasites & Vectors, 2020
Background Knockdown resistance (kdr) is the main mechanism that confers resistance to pyrethroids and DDT. This is a product of non-synonymous mutations in the voltage-gated sodium channel (vgsc) gene, and these mutations produce a change of a single ...
Karina Villanueva-Segura, Gustavo Ponce-Garcia, Beatriz Lopez-Monroy, Esteban Mora-Jasso, Lucia Perales, Francisco J. Gonzalez-Santillan, Kevin Ontiveros-Zapata, Jesus A. Davila-Barboza, Adriana E. Flores   +8 more
doaj   +1 more source