Results 11 to 20 of about 23,841 (197)

KDR activation in astrocytic neoplasms [PDF]

Cancer, 1999
The development of new capillary networks appears to be necessary for the growth of solid tumors. Tumor angiogenesis is believed to be mediated by soluble factors released from tumor cells that then act on endothelial cells in a paracrine manner. Vascular endothelial growth factor (VEGF) is a prime regulator of normal and tumor angiogenesis as well as ...
R. S. Carroll, J. Zhang, L. Bello, M. B. Melnick, T. Maruyama, P. Mcl Black   +5 more
openaire   +4 more sources

Association of VEGF and KDR polymorphisms with the development of schizophrenia [PDF]

Human Immunology, 2021
Abstract Aim Several approaches indicate different blood flow disturbances in schizophrenia (Scz). Vascular endothelial growth factor (VEGF) is widely recognized as one of the key molecules implicated in the angiogenesis process through mainly its receptor KDR.
Hana, Saoud, Youssef, Aflouk, Amira, Ben Afia, Lotfi, Gaha, Besma, Bel Hadj Jrad   +4 more
openaire   +2 more sources

Liver progenitor cell and KDR [PDF]

Cell Cycle, 2014
Liver disease affects hundreds of millions of patients worldwide. Liver transplantation is currently the only curable treatment for liver failure caused by cirrhosis, chronic hepatitis B or C, bile duct disease, genetic disease, autoimmune liver disease, primary liver cancer, alcoholic liver disease, or fatty liver disease.
Han, Songyan, Goldman, Orit, Gouon-Evans, Valerie   +2 more
openaire   +2 more sources

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Multiplex PCR for simultaneous genotyping of kdr mutations V410L, V1016I and F1534C in Aedes aegypti (L.)

Parasites & Vectors, 2020
Background Knockdown resistance (kdr) is the main mechanism that confers resistance to pyrethroids and DDT. This is a product of non-synonymous mutations in the voltage-gated sodium channel (vgsc) gene, and these mutations produce a change of a single ...
Karina Villanueva-Segura, Gustavo Ponce-Garcia, Beatriz Lopez-Monroy, Esteban Mora-Jasso, Lucia Perales, Francisco J. Gonzalez-Santillan, Kevin Ontiveros-Zapata, Jesus A. Davila-Barboza, Adriana E. Flores   +8 more
doaj   +1 more source

Assessing the effects of Aedes aegypti kdr mutations on pyrethroid resistance and its fitness cost. [PDF]

PLoS ONE, 2013
Pyrethroids are the most used insecticide class worldwide. They target the voltage gated sodium channel (NaV), inducing the knockdown effect. In Aedes aegypti, the main dengue vector, the AaNaV substitutions Val1016Ile and Phe1534Cys are the most ...
Luiz Paulo Brito, Jutta G B Linss, Tamara N Lima-Camara, Thiago A Belinato, Alexandre A Peixoto, José Bento P Lima, Denise Valle, Ademir J Martins   +7 more
doaj   +1 more source

Molecular analysis of knockdown resistance (kdr) mutations in the voltage-gated sodium channel gene of Aedes aegypti populations from Saudi Arabia

Parasites & Vectors, 2022
Background The Aedes aegypti mosquito is the primary vector for dengue, chikungunya, yellow fever and Zika viruses worldwide. The first record of Ae. aegypti in southwestern Saudi Arabia was in 1956.
Abadi M. Mashlawi, Ashwaq M. Al-Nazawi, Elsiddig M. Noureldin, Hussain Alqahtani, Jazem A. Mahyoub, Jassada Saingamsook, Mustapha Debboun, Martha Kaddumukasa, Hesham M. Al-Mekhlafi, Catherine Walton   +9 more
doaj   +1 more source

Investigating insecticide resistance and knock-down resistance (kdr) mutation in Dielmo, Senegal, an area under long lasting insecticidal-treated nets universal coverage for 10 years

Malaria Journal, 2018
Background The use of insecticides, through indoor residual spraying and long-lasting insecticide-treated nets (LLINs), is essential to control malaria vectors.
Omar Thiaw, Souleymane Doucouré, Seynabou Sougoufara, Charles Bouganali, Lassana Konaté, Nafissatou Diagne, Ousmane Faye, Cheikh Sokhna   +7 more
doaj   +1 more source

Genome-wide Association Study Reveals New Loci Associated With Pyrethroid Resistance in Aedes aegypti

Frontiers in Genetics, 2022
Genome-wide association studies (GWAS) use genetic polymorphism across the genomes of individuals with distinct characteristics to identify genotype-phenotype associations.
Luciano V. Cosme, José Bento Pereira Lima, Jeffrey R. Powell, Ademir Jesus Martins, Ademir Jesus Martins   +4 more
doaj   +1 more source

Resistance to Permethrin, β-cyfluthrin, and Diazinon in Florida Horn Fly Populations

Insects, 2018
Horn flies, Haematobia irritans, a major cattle pest in the USA, cause substantial economic losses and current control methods rely heavily on insecticides.
Chris J. Holderman, Daniel R. Swale, Jeffery R. Bloomquist, Phillip E. Kaufman   +3 more
doaj   +1 more source