Results 21 to 30 of about 23,687 (206)

Genome-wide Association Study Reveals New Loci Associated With Pyrethroid Resistance in Aedes aegypti

Frontiers in Genetics, 2022
Genome-wide association studies (GWAS) use genetic polymorphism across the genomes of individuals with distinct characteristics to identify genotype-phenotype associations.
Luciano V. Cosme, José Bento Pereira Lima, Jeffrey R. Powell, Ademir Jesus Martins, Ademir Jesus Martins   +4 more
doaj   +1 more source

Evolution of kdr haplotypes in worldwide populations of Aedes aegypti: Independent origins of the F1534C kdr mutation

PLOS Neglected Tropical Diseases, 2020
Aedes aegypti is the primary vector of dengue, chikungunya, Zika, and urban yellow fever. Insecticides are often the most effective tools to rapidly decrease the density of vector populations, especially during arbovirus disease outbreaks. However, the intense use of insecticides, particularly pyrethroids, has selected for resistant mosquito ...
Luciano Veiga Cosme, Andrea Gloria-Soria, Adalgisa Caccone, Jeffrey Robert Powell, Ademir Jesus Martins   +4 more
openaire   +3 more sources

Investigating insecticide resistance and knock-down resistance (kdr) mutation in Dielmo, Senegal, an area under long lasting insecticidal-treated nets universal coverage for 10 years

Malaria Journal, 2018
Background The use of insecticides, through indoor residual spraying and long-lasting insecticide-treated nets (LLINs), is essential to control malaria vectors.
Omar Thiaw, Souleymane Doucouré, Seynabou Sougoufara, Charles Bouganali, Lassana Konaté, Nafissatou Diagne, Ousmane Faye, Cheikh Sokhna   +7 more
doaj   +1 more source

Resistance to Permethrin, β-cyfluthrin, and Diazinon in Florida Horn Fly Populations

Insects, 2018
Horn flies, Haematobia irritans, a major cattle pest in the USA, cause substantial economic losses and current control methods rely heavily on insecticides.
Chris J. Holderman, Daniel R. Swale, Jeffery R. Bloomquist, Phillip E. Kaufman   +3 more
doaj   +1 more source

ECSCR enhances KDR activation and promotes proteolysis of internalized KDR (LB160)

The FASEB Journal, 2014
The endothelial cell‐specific chemotaxis receptor (ECSCR) is a cell‐surface protein selectively expressed by endothelial cells (ECs), with roles in EC migration, apoptosis and proliferation. Our previous study showed that loss of ECSCR in primary ECs reduced tyrosine phosphorylation of vascular endothelial growth factor (VEGF) receptor 2/kinase insert ...
George Wilkinson, Sreenivas Kilari, Indulekha Remadevi, Baofeng Baofeng Zhao, Jing Pan, Robert Miao, Ramani Ramchandran, Paula North, Ming You, Nader Rahimi   +9 more
openaire   +1 more source

Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture againstKdr- andKdr+ malaria vectors (Anopheles gambiae) [PDF]

Parasite, 2003
In order to prevent the resistance of Anopheles gambiae s.l. to pyrethroids from spreading too quickly and to lengthen the effectiveness of insecticide impregnated mosquito nets, it has recently been suggested to use mixtures of insecticides that have different modes of action.
/Darriet, Frédéric, /Corbel, Vincent, /Hougard, Jean-Marc   +2 more
openaire   +4 more sources

Malaria vectors in the Democratic Republic of the Congo: the mechanisms that confer insecticide resistance in Anopheles gambiae and Anopheles funestus

Malaria Journal, 2017
Background The Democratic Republic of the Congo (DRC) is characterized as a holoendemic malaria area with the main vectors being Anopheles funestus and members of the Anopheles gambiae complex.
Luisa Nardini, Richard H. Hunt, Yael L. Dahan-Moss, Nanette Christie, Riann N. Christian, Maureen Coetzee, Lizette L. Koekemoer   +6 more
doaj   +1 more source

A combination of metabolic resistance and high frequency of the 1014F kdr mutation is driving pyrethroid resistance in Anopheles coluzzii population from Guinea savanna of Cameroon

Parasites & Vectors, 2019
Background The scale-up in the distribution of long-lasting insecticidal nets (LLINs) and indoor residual spraying has significantly reduced malaria burden and mortality.
Amen N. Fadel, Sulaiman S. Ibrahim, Magellan Tchouakui, Ebai Terence, Murielle J. Wondji, Micareme Tchoupo, Samuel Wanji, Charles S. Wondji   +7 more
doaj   +1 more source

First report of kdr mutations in the voltage-gated sodium channel gene in the arbovirus vector, Aedes aegypti, from Nouakchott, Mauritania

Parasites & Vectors, 2023
Background Since 2014, dengue epidemics have occurred almost annually in Nouakchott, the capital city of Mauritania, coinciding with the recent establishment of Aedes aegypti, the primary vector of dengue, in the city.
Mohamed Aly Ould Lemrabott, Sébastien Briolant, Nicolas Gomez, Leonardo Basco, Ali Ould Mohamed Salem Boukhary   +4 more
doaj   +1 more source

The role of KDR in intrauterine adhesions may involve the TGF-β1/Smads signaling pathway

Brazilian Journal of Medical and Biological Research
The aim of this study was to investigate the role of kinase-insert domain-containing receptor (KDR) in intrauterine adhesions (IUA) and its mechanism. The Case group consisted of 92 patients diagnosed with IUA, and the Control group included 86 patients ...
Jian Xia Chen, Xi Juan Yi, Pei Ling Gu, Shan Xia Gao   +3 more
doaj   +1 more source