Results 151 to 160 of about 245,138 (311)

Exploring the mechanism of action of Kaixin San in treating dementia based on network pharmacology and molecular docking. [PDF]

Medicine (Baltimore)
Liu S, Zhang Z.
europepmc   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Molecular mechanisms of disinfectant resistance in <i>Klebsiella pneumoniae</i>. [PDF]

JAC Antimicrob Resist
Noel DJ, Bailey A, Nicholas BI, Skipp P, Keevil CW, Wilks SA.   +5 more
europepmc   +1 more source

GO and KEGG analysis results of PA against osteosarcoma.

Zeyu Zhan (22305085), He Pang (22305088), Hang Wu (5072618), Lijun Song (1899229), Bo Wei (188204)   +4 more
openalex   +1 more source

kegg

, 2018
Bo Liu
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

The possibility of prognostic and functional values of the 8q24 and 20q13 chromosomal bands in colorectal cancer. [PDF]

Mol Biol Res Commun
Siadat SA.
europepmc   +1 more source

Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses of key candidate genes associated with ES-PMMA. (A, B). Results of GO enrichment analysis; (C, D). Results of KEGG enrichment analysis. Each module represents each pathway, the size of the module represents the level of gene expression in the pathway, and the color represents the P-value.

Xiaoyu Shen (4715430), Qiang Yao (1261140), Lijie Ma (755998)   +2 more
openalex   +1 more source

Singular enrichment of GO (or KEGG) categories in gene clusters uncovered by LRR from yeast dataset.

, 2015
Yan Cui, Zheng Chun-Hou, Yang Jian
openalex   +2 more sources

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source