Keratin Dynamics: Modeling the Interplay between Turnover and Transport [PDF]
Keratin are among the most abundant proteins in epithelial cells. Functions of the keratin network in cells are shaped by their dynamical organization. Using a collection of experimentally-driven mathematical models, different hypotheses for the turnover
Chung, Andy+4 more
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Early studies have already shown that the tonofibrils of malpighian cells consist of a --SH containing fibrous alpha-protein. It was assumed that the highly resistant protective substance, keratin, was formed by the conversion of --SH groups into --S--S--bonds in this protein.
K, Fukuyama+3 more
openaire +4 more sources
The molecular genetic analysis of the expanding pachyonychia congenita case collection [PDF]
BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis.
Al-Asadi, E.+9 more
core +2 more sources
Valorization of keratin biofibers for removing heavy metals from aqueous solutions [PDF]
Four common waste keratin biofibers (human hair, dog hair, chicken feathers, and degreased wool) have been used as biosorbents for the removal of heavy metal ions from aqueous solutions. Different parameters of the biosorption processes were optimized in
Carrillo Navarrete, Fernando+3 more
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Non-invasive depth profiling of the stratum corneum in vivo using confocal Raman microscopy considering the non-homogeneous distribution of keratin [PDF]
Confocal Raman microscopy has a number of advantages in investigating the human stratum corneum (SC) in vivo and ex vivo. The penetration profiles of xenobiotics in the SC, as well as depth profiles of the physiological parameters of the SC, such as the ...
Choe, Chun-Sik+3 more
core +1 more source
Sedimentation Studies of Epidermal Keratins. Keratin A and Keratin B [PDF]
Electrophoretically homogeneous keratin A and keratin B were studied in the ultracentrifuge. Both preparations revealed two fractions: one which sedimented rapidly and another which sedimented slowly. This indicated that both preparations are heterogeneous with respect to particle size.
openaire +3 more sources
Laccase-assisted approach to graft multifunctional materials of interest: keratin-EC based novel composites and their characterisation [PDF]
This study focuses on the evaluation of raw keratin as a potential material to develop composites with novel characteristics. Herein, we report a mild and eco-friendly fabrication of in-house extracted feather keratin-based novel enzyme assisted ...
Aljawish+36 more
core +1 more source
Structural validation of oral mucosal tissue using optical coherence tomography [PDF]
Background: Optical coherence tomography (OCT) is a non-invasive optical technology using near-infrared light to produce cross-sectional tissue images with lateral resolution.
Al-Delayme, R+5 more
core +1 more source
Pathophysiology of keratinization
Cytoskeleton of a cell is made up of microfilaments, microtubules and intermediate filaments. Keratins are diverse proteins. These intermediate filaments maintain the structural integrity of the keratinocytes. The word keratin covers these intermediate filament-forming proteins within the keratinocytes.
Revati Deshmukh, Priya Nimish Deo
openaire +3 more sources
Transient activaton of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours [PDF]
When β-catenin signalling is disturbed from mid-gestation onwards lineage commitment is profoundly altered in postnatal mouse epidermis. We have investigated whether adult epidermis has the capacity for β-catenin-induced lineage conversion without prior ...
Celso, Cristina Lo+2 more
core +1 more source