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Keratin Dynamics: Modeling the Interplay between Turnover and Transport [PDF]

open access: yesPLoS ONE, 2015
Keratin are among the most abundant proteins in epithelial cells. Functions of the keratin network in cells are shaped by their dynamical organization. Using a collection of experimentally-driven mathematical models, different hypotheses for the turnover
Chung, Andy   +4 more
core   +6 more sources

Keratinization

open access: yesJournal of Investigative Dermatology, 1976
Early studies have already shown that the tonofibrils of malpighian cells consist of a --SH containing fibrous alpha-protein. It was assumed that the highly resistant protective substance, keratin, was formed by the conversion of --SH groups into --S--S--bonds in this protein.
K, Fukuyama   +3 more
openaire   +4 more sources

The molecular genetic analysis of the expanding pachyonychia congenita case collection [PDF]

open access: yes, 2014
BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis.
Al-Asadi, E.   +9 more
core   +2 more sources

Valorization of keratin biofibers for removing heavy metals from aqueous solutions [PDF]

open access: yes, 2018
Four common waste keratin biofibers (human hair, dog hair, chicken feathers, and degreased wool) have been used as biosorbents for the removal of heavy metal ions from aqueous solutions. Different parameters of the biosorption processes were optimized in
Carrillo Navarrete, Fernando   +3 more
core   +2 more sources

Non-invasive depth profiling of the stratum corneum in vivo using confocal Raman microscopy considering the non-homogeneous distribution of keratin [PDF]

open access: yes, 2019
Confocal Raman microscopy has a number of advantages in investigating the human stratum corneum (SC) in vivo and ex vivo. The penetration profiles of xenobiotics in the SC, as well as depth profiles of the physiological parameters of the SC, such as the ...
Choe, Chun-Sik   +3 more
core   +1 more source

Sedimentation Studies of Epidermal Keratins. Keratin A and Keratin B [PDF]

open access: yesThe Journal of Cell Biology, 1956
Electrophoretically homogeneous keratin A and keratin B were studied in the ultracentrifuge. Both preparations revealed two fractions: one which sedimented rapidly and another which sedimented slowly. This indicated that both preparations are heterogeneous with respect to particle size.
openaire   +3 more sources

Laccase-assisted approach to graft multifunctional materials of interest: keratin-EC based novel composites and their characterisation [PDF]

open access: yes, 2015
This study focuses on the evaluation of raw keratin as a potential material to develop composites with novel characteristics. Herein, we report a mild and eco-friendly fabrication of in-house extracted feather keratin-based novel enzyme assisted ...
Aljawish   +36 more
core   +1 more source

Structural validation of oral mucosal tissue using optical coherence tomography [PDF]

open access: yes, 2012
Background: Optical coherence tomography (OCT) is a non-invasive optical technology using near-infrared light to produce cross-sectional tissue images with lateral resolution.
Al-Delayme, R   +5 more
core   +1 more source

Pathophysiology of keratinization

open access: yesJournal of Oral and Maxillofacial Pathology, 2018
Cytoskeleton of a cell is made up of microfilaments, microtubules and intermediate filaments. Keratins are diverse proteins. These intermediate filaments maintain the structural integrity of the keratinocytes. The word keratin covers these intermediate filament-forming proteins within the keratinocytes.
Revati Deshmukh, Priya Nimish Deo
openaire   +3 more sources

Transient activaton of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours [PDF]

open access: yes, 2004
When β-catenin signalling is disturbed from mid-gestation onwards lineage commitment is profoundly altered in postnatal mouse epidermis. We have investigated whether adult epidermis has the capacity for β-catenin-induced lineage conversion without prior ...
Celso, Cristina Lo   +2 more
core   +1 more source

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