Results 1 to 10 of about 76,105 (258)

Multiprotein collagen/keratin hydrogel promoted myogenesis and angiogenesis of injured skeletal muscles in a mouse model

BMC Biotechnology
Volumetric loss is one of the challenging issues in muscle tissue structure that causes functio laesa. Tissue engineering of muscle tissue using suitable hydrogels is an alternative to restoring the physiological properties of the injured area.
Atieh Rezaei Namjoo, Ayla Hassani, Hassan Amini, Fateme Nazaryabrbekoh, Sepideh Saghati, Mohammad Ali Ebrahimi Saadatlou, Ali Baradar Khoshfetrat, Nafiseh Didar Khosrowshahi, Reza Rahbarghazi   +8 more
doaj   +1 more source

Deacetylation via SIRT2 prevents keratin-mutation-associated injury and keratin aggregation

JCI Insight, 2023
Keratin (K) and other intermediate filament (IF) protein mutations at conserved arginines disrupt keratin filaments into aggregates and cause human epidermolysis bullosa simplex (EBS; K14-R125C) or predispose to mouse liver injury (K18-R90C).
Jingyuan Sun, Pei Li, Honglian Gui, Laure Rittié, David B. Lombard, Katrin Rietscher, Thomas M. Magin, Qing Xie, Li Liu, M. Bishr Omary   +9 more
doaj   +1 more source

Effects of Plectin Depletion on Keratin Network Dynamics and Organization. [PDF]

PLoS ONE, 2016
The keratin intermediate filament cytoskeleton protects epithelial cells against various types of stress and is involved in fundamental cellular processes such as signaling, differentiation and organelle trafficking. These functions rely on the cell type-
Marcin Moch, Reinhard Windoffer, Nicole Schwarz, Raphaela Pohl, Andreas Omenzetter, Uwe Schnakenberg, Fabian Herb, Kraisorn Chaisaowong, Dorit Merhof, Lena Ramms, Gloria Fabris, Bernd Hoffmann, Rudolf Merkel, Rudolf E Leube   +13 more
doaj   +1 more source

Optimizing the Extraction of Keratin from Cattle Hoof Using Central Composite Design

Advances in Materials Science and Engineering, 2022
Cattle hoofs are abundantly available by-product sources of organic material from the slaughterhouse. It can be successfully converted into keratin protein. Keratin extracted using alkali hydrolysis has a better conservancy of keratin structure.
Kelem Tiessasie Yilma, Tamrat Tesfaye, Haymanot Enawgaw, Million Ayele, Derseh Yilie Limeneh, Magdi Gibril, Fangong Kong   +6 more
doaj   +1 more source

Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules.

PLoS ONE, 2014
Epiplakin, a member of the plakin protein family, is exclusively expressed in epithelial tissues and was shown to bind to keratins. Epiplakin-deficient (EPPK-/-) mice showed no obvious spontaneous phenotype, however, EPPK-/- keratinocytes displayed ...
Karl L Wögenstein, Sandra Szabo, Mariia Lunova, Gerhard Wiche, Johannes Haybaeck, Pavel Strnad, Peter Boor, Martin Wagner, Peter Fuchs   +8 more
doaj   +1 more source

Valorization of Chicken Feather Keratin as an Eco-Friendly Coagulant for Ochre Dye Removal: A Sustainable Approach

Alchemy
This study examines the extraction of keratin from chicken feather waste and its potential use as a coagulant in ochre dye solution treatment. The extraction procedure was investigated for the effect of some parameters, such as temperature (60 – 80 °C ...
Sri Wahyu Murni, Tutik Muji Setyoningrum, Alim Nurjanah, Sandika Perdana Putra   +3 more
doaj   +1 more source

Keratin Retraction and Desmoglein3 Internalization Independently Contribute to Autoantibody-Induced Cell Dissociation in Pemphigus Vulgaris

Frontiers in Immunology, 2018
Pemphigus vulgaris (PV) is a potentially lethal autoimmune disease characterized by blister formation of the skin and mucous membranes and is caused by autoantibodies against desmoglein (Dsg) 1 and Dsg3.
Elisabeth Schlögl, Mariya Y. Radeva, Franziska Vielmuth, Camilla Schinner, Jens Waschke, Volker Spindler, Volker Spindler   +6 more
doaj   +1 more source

Loss of the keratin cytoskeleton is not sufficient to induce epithelial mesenchymal transition in a novel KRAS driven sporadic lung cancer mouse model.

PLoS ONE, 2013
Epithelial-to-mesenchymal transition (EMT), the phenotypical change of cells from an epithelial to a mesenchymal type, is thought to be a key event in invasion and metastasis of adenocarcinomas. These changes involve loss of keratin expression as well as
Katharina König, Lydia Meder, Cornelia Kröger, Linda Diehl, Alexandra Florin, Ursula Rommerscheidt-Fuss, Philip Kahl, Eva Wardelmann, Thomas M Magin, Reinhard Buettner, Lukas C Heukamp   +10 more
doaj   +1 more source

Extraction of Keratin from Chicken Feathers and its Application in the Treatment of Contaminated Water: an Eco-Friendly Approach

Brazilian Archives of Biology and Technology
Chicken feathers that make up 4-6% of total weight of chicken are most influential waste by-product from poultry farm and slaughter. Annual worldwide generation of several tons of feather biomass raise solid waste management concerns.
Sumaira Amin, Moneeza Abbas, Houda Javed, Zahra Asghar, Nadia Ghani, Shabnum Shaheen, Faiza Hassan, Rabia Akram, Hafiza Sana Yousaf   +8 more
doaj   +1 more source

Synthesis and Characterization of Keratin-Based Scaffold for Potential Tissue Engineering Applications

Fibers
Keratin, a fibrous structural protein, has been employed as a biomaterial for hemostasis and tissue repair due to its structural stability, mechanical strength, biocompatibility, and biodegradability.
Murugiah Krishani, Jia Ning Chong, Wan Rong Lim, Norwahyu Jusoh, Nonni Soraya Sambudi, Hazwani Suhaimi   +5 more
doaj   +1 more source