Results 21 to 30 of about 8,643,049 (268)

The pancreatic and duodenal homeobox protein PDX-1 regulates the ductal specific keratin 19 through the degradation of MEIS1 and DNA binding. [PDF]

PLoS ONE, 2010
Pancreas organogenesis is the result of well-orchestrated and balanced activities of transcription factors. The homeobox transcription factor PDX-1 plays a crucial role in the development and function of the pancreas, both in the maintenance of ...
Johannes von Burstin, Maximilian Reichert, Melanie P Wescott, Anil K Rustgi   +3 more
doaj   +2 more sources

Keratin 13 is a more specific marker of conjunctival epithelium than keratin 19

Molecular vision, 2011
Purpose To evaluate the expression patterns of cytokeratin (K) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether K13 could be used as a marker for conjunctival epithelium.
A. Ramirez-Miranda, Martin N. Nakatsu, S. Zarei-Ghanavati, Christine V. Nguyen, Sophie X. Deng   +4 more
semanticscholar   +4 more sources

Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours [PDF]

Comparative Hepatology, 2010
BackgroundThe expression of Keratin 19 (K19) was reported in a subset of hepatocellular carcinomas (HCCs). K19 positive HCCs are associated with an increased malignancy compared to K19 negative HCCs. No suitable mouse models exist for this subtype of HCC,
Renee G. H. M. van Sprundel, T. V. D. van den Ingh, V. Desmet, A. Katoonizadeh, L. Penning, J. Rothuizen, T. Roskams, B. Spee   +7 more
semanticscholar   +3 more sources

The correlation of keratin expression with in-vitro epithelial cell line differentiation [PDF]

, 2009
MPhil 2009 QMThe mechanism of transcriptional regulation which allows oral mucosal-specific expression of the human keratin 13 (K13) gene remains unknown.
Aden, Deeqo
core   +4 more sources

Carcinomas assemble a filamentous CXCL12–keratin-19 coating that suppresses T cell–mediated immune attack

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance Carcinomas resist immunotherapy because T cells are absent from nests of cancer cells. The chemokine/chemokine receptor system, which regulates the migration of immune cells, is a candidate for this impaired intratumoral accumulation of T ...
Zhikai Wang, Philip Moresco, Ran Yan, Jiayun Li, Ya Gao, D. Biasci, M. Yao, Jordan Pearson, J. Hechtman, T. Janowitz, Raza M. Zaidi, M. Weiss, D. Fearon   +12 more
semanticscholar   +1 more source

DNA methylation‐associated allelic inactivation regulates Keratin 19 gene expression during pancreatic development and carcinogenesis

Journal of Pathology, 2023
Within the pancreas, Keratin 19 (KRT19) labels the ductal lineage and is a determinant of pancreatic ductal adenocarcinoma (PDAC). To investigate KRT19 expression dynamics, we developed a human pluripotent stem cell (PSC)‐based KRT19‐mCherry reporter ...
J. Krüger, Anja Fischer, M. Breunig, C. Allgöwer, L. Schulte, J. Merkle, M. Mulaw, N. Okeke, M. Melzer, Clara Morgenstern, N. Azoitei, T. Seufferlein, T. Barth, R. Siebert, M. Hohwieler, A. Kleger   +15 more
semanticscholar   +1 more source

Improving the Adsorption Properties of Keratin-Based Goat Hair Toward Reactive Dyes in Dyeing Wastewater by Steam Explosion

Journal of Natural Fibers, 2023
Keratin-based goat hair could be used bioadsorbent due to its large availability, biodegradability and low cost. Unfortunately, most available keratin adsorbents are either low in adsorption capacity or high in preparation cost.
Shijin Wei, Xiuliang Hou, Linyun Liu, Yue Tian, Wei Li, Helan Xu   +5 more
doaj   +1 more source

Efficient isolation of keratin from protein-rich waste biomass: a practical approach to minimize environmental impact and valorize waste biomass

Sustainable Environment Research, 2022
Among various protein-containing biomass wastes, waste animal wool, poultry feather, and human hair are considered one of the most important renewable sources of keratin.
Tapan Kumar Maity, Nripat Singh, Pradipkumar Vaghela, Arup Ghosh, Sanju Singh, Pramod B. Shinde, Rosy Alphons Sequeira, Kamalesh Prasad   +7 more
doaj   +1 more source

Keratin 19 Epithelial Patterns in Cirrhotic Stroma Parallel Hepatocarcinogenesis [PDF]

The American Journal of Pathology, 2011
Cirrhotic septa harbor vessels and inflammatory, fibrogenic, and ductular epithelial cells, collectively referred to as the ductular reaction (DR). Lack of the DR in the stromal compartment around hepatocellular carcinoma (HCC) has been documented; however, the relationship of epithelial keratin 19 (K19) structures to progression of intralesional ...
Jochen K M, Lennerz, William C, Chapman, Elizabeth M, Brunt   +2 more
openaire   +2 more sources

No difference in keratin thickness between inner and outer foreskins from elective male circumcisions in Rakai, Uganda. [PDF]

PLoS ONE, 2012
It has been hypothesized that increased HIV acquisition in uncircumcised men may relate to a more thinly keratinized inner foreskin. However, published data are contradictory and potentially confounded by medical indications for circumcision.
Minh H Dinh, Taha Hirbod, Godfrey Kigozi, Eneniziaogochukwu A Okocha, Gianguido C Cianci, Xiangrong Kong, Jessica L Prodger, Kristina Broliden, Rupert Kaul, David Serwadda, Maria J Wawer, Ronald H Gray, Thomas J Hope   +12 more
doaj   +1 more source