Results 231 to 240 of about 8,643,049 (268)

Medullary carcinoma of the breast: a tumour lacking keratin 19

Histopathology, 1994
The presence of keratin 19 (K19) was searched for by immunostaining in 16 medullary carcinomas, comprising 12 typical and four atypical cases, in 29 undifferentiated high‐grade carcinomas (NOS‐HG) with conspicuous lymphoid response and in 12 well differentiated low‐grade carcinomas (NOS‐LG).
Larsimont, Denis, Lespagnard, Laurence, Degeyter, Marianne, Heimann, Rudolf   +3 more
openaire   +3 more sources

Keratin 19‐expressing hepatocellular carcinoma and small‐duct type intrahepatic cholangiocarcinoma show a similar postoperative clinical course but have distinct genetic features

Histopathology, 2019
The present study aimed to systematically compare clinicopathological and genetic features between keratin 19 (K19)‐expressing hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA).
Masayuki Akita, T. Ajiki, T. Fukumoto, T. Itoh, Y. Zen   +4 more
semanticscholar   +1 more source

Keratin 19 expression in the adult and developing human mammary gland

The Histochemical Journal, 1990
In the adult human mammary gland, most of the luminal epithelial cells express keratin 19 (K19+). However, in some small ducts and terminal ductal lobular units where branching would be expected to occur during pregnancy, the pattern of expression of this keratin is heterogeneous.
J, Bartek, J, Bartkova, J, Taylor-Papadimitriou   +2 more
openaire   +2 more sources

Keratin 19 in the adult human prostate: tissue and cell culture studies

Cell and Tissue Research, 1996
Keratin 19 is found primarily in simple epithelia. In mammary epithelia, keratin 19 was localized to a subset of luminal cells, suggesting that keratin 19-negative cells may be the proliferative compartment of the secretory cell lineage. The structural and functional similarities of prostate and breast led us to examine keratin 19 expression in the ...
D M, Peehl, R G, Sellers, J E, McNeal
openaire   +2 more sources

The mouse keratin 19-encoding gene: sequence, structure and chromosomal assignment

Gene, 1990
Keratin 19 (K19) is synthesized mainly in embryonic and adult simple epithelia, but has also been found in stratified epithelia as well. K19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is ...
Lussier, M, Filion, M, Compton, J G, Nadeau, J H, Lapointe, L, Royal, A   +5 more
openaire   +2 more sources

Keratin 19-like immunoreactivity in receptor cells of mammalian taste buds

Chemical Senses, 1994
Three monoclonal antibodies, 4.62, LP2K and 170.2.14, were used to evaluate keratin 19-like immunoreactivity in gustatory epithelia. Keratin 19-like immunoreactivity was restricted to the intragemmal cells for all types of mammalian taste buds examined.
L, Wong, B, Oakley, A, Lawton, Y, Shiba
openaire   +2 more sources

The keratin 19 promoter is potent for cell-specific targeting of genes in transgenic mice

Gastroenterology, 2001
Keratins are intermediate filaments that are critical in cytoskeletal organization. Their roles in cellular processes are underscored by inherited human diseases in which germline mutations of keratins are found, as well as by transgenic and knockout mouse models that recapitulate those diseases.
F H, Brembeck, J, Moffett, T C, Wang, A K, Rustgi   +3 more
openaire   +2 more sources

Keratin 19 Downregulation by Oral Squamous Cell Carcinoma Lines Increases Invasive Potential

Journal of Dental Research, 1999
Squamous cell carcinoma (SCC) of the head and neck is the sixth most frequent cancer worldwide. The survival rate is among the lowest of the major cancers and has not improved significantly in the past two decades. Extensive local invasion and regional lymph node metastasis are, in large part, responsible for the poor clinical outcome of these tumors ...
D L, Crowe, G E, Milo, C F, Shuler
openaire   +2 more sources

Retinoic acid mediates post-transcriptional regulation of keratin 19 mrna levels

Journal of Cell Science, 1993
ABSTRACT Stratified squamous epithelia have been shown to preferentially express a site-specific pattern of keratin intermediate filaments. Retinoic acid (RA) is known to modulate expression of the basal cell keratins K19 and K5. Expression of these genes is dependent on extracellular RA concentration.
openaire   +2 more sources

Novel HMGA2::COL14A1 Fusion Identified in Xanthogranulomatous Epithelial Tumor/Keratin‐Positive Giant Cell Tumor

Genes, Chromosomes and Cancer
Xanthogranulomatous epithelial tumor (XGET)/Keratin‐positive giant cell tumor (KP‐GCT) represents a spectrum of recently described neoplasms characterized by a proliferation of distinctive mononuclear cells expressing keratin within a background of ...
Carina A. Dehner, D. Buehler, Christopher D. Hofich, K. Halling, A. Folpe   +4 more
semanticscholar   +1 more source