Results 81 to 90 of about 4,292,812 (187)

One-Pot Synthesis of Chicken-Feather-Keratin-Based Prodrug Nanoparticles with High Drug Content for Tumor Intracellular DOX Delivery

open access: yes, 2019
pH/reduction dual-triggered chicken-feather-keratin-based prodrug nanoparticles (C-PK/-SS-Hy-D NPs) were designed via a facile one-pot oxidation coupling reaction between the thiol-functional acid-labile prodrug M-Hy-D and the PEGylated keratin (PK ...
Peng Liu (120506)   +3 more
core   +1 more source

Keratin coated titanium as an aid to osseointegration: Physicochemical and mechanical properties

open access: yes, 2023
Wool-extracted keratin has been shown to promote bone formation in vivo and may therefore be a potential novel bioactive coating material for osseous implants.
Love, Robert M   +5 more
core   +1 more source

Expression pattern of keratin 14.

open access: yes, 2015
Paraffin-embedded sections of human term placenta are stained with keratin 14 (CK14) along with Vimentin, keratin 19 (CK19), keratin 8 (CK8) and keratin 7 (CK7). Dapi is used to counterstain the nucleus. Representative images of 3 different placentas are
Wassim Abou-Kheir (201647)   +4 more
core   +1 more source

Actomyosin forces trigger a conformational change in desmoplakin within desmosomes

open access: yesNature Communications
Desmosomes are essential cell-cell adhesion organelles that enable tension-prone tissues, like the skin and heart, to withstand mechanical stress.
Yinchen Dong   +6 more
doaj   +1 more source

Cellular expansion of hepatocellular carcinoma organoids using decellularized liver scaffolds

open access: yesClinical Transplantation and Research
Background : A decellularized liver scaffold (DLS) is a three-dimensional acellular extracellular matrix created by removing cellular components from liver tissue. Hepatocellular carcinoma (HCC) organoids represent a useful experimental model.
Shin Hwang   +4 more
doaj   +1 more source

Age and the means of bypassing stasis are determinants of the intrinsic subtypes of immortalized human mammary epithelial cells

open access: yesFrontiers in Cell and Developmental Biology, 2015
Based on molecular features, breast cancers are grouped into intrinsic subtypes that have different prognoses and therapeutic response profiles. With increasing age, breast cancer incidence increases, with hormone receptor-positive and other luminal-like
Jonathan K Lee   +4 more
doaj   +1 more source

TESCALCIN OVER-EXPRESSION INCREASES KERATIN 18 AND 19 IN K562 CELLS

open access: yes, 2022
Purpose: Tescalcin (TESC) has been shown to be essential in mammalian cells as a regulator of intracellular Ca2+. Ca2+ is a second messenger functioning in many metabolic pathways as well as in cell differentiation, cell size and the cell cycle.
Yoca, Ozge Uysal   +3 more
core   +1 more source

HERC4 downregulates KRT19 to promote lung adenocarcinoma, migration, invasion and EMT

open access: yesTranslational Oncology
Background: Metastasis is a major cause of treatment failure and poor prognosis in lung adenocarcinoma (LUAD). Epithelial-mesenchymal transition (EMT) plays a crucial role in promoting LUAD metastasis.
Hao-Jia Sun   +4 more
doaj   +1 more source

Periocular keratoacanthoma: A clinicopathologic study and diagnostic challenges

open access: yesThe Pan-American Journal of Ophthalmology
Purpose: Keratoacanthoma (KA) is a cutaneous neoplasm that presents as a rapidly growing tumor on ultraviolet light-exposed skin. It appears as an exophytic, crater-like lesion filled with keratin. In periocular sites, the eyelids are most often affected.
Eduardo Ballalai Bordon   +7 more
doaj   +1 more source

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