Results 111 to 120 of about 56,092 (227)

Silver Sulfadiazine's Effect on Keratin-19 Expression as Stem Cell Marker in Burn Wound Healing. [PDF]

Biomedicine (Taipei), 2020
Sukmawati D, Eryani A, Damayanti L.
europepmc   +1 more source

Effect of Notch1 on Vocal Fold Re‐Epithelization After Acute Injury

The Laryngoscope, EarlyView.
Conditional deletion of Notch1 in Lrig1‐expressing vocal fold epithelial cells impaired re‐epithelialization following naphthalene injury, resulting in sustained basal cell proliferation, abnormal epithelial differentiation, and prolonged inflammatory cell infiltration.
Jie Cai, Susan L Thibeault, Vlasta Lungova   +2 more
wiley   +1 more source

Global Multidisciplinary Variation in Idiopathic Subglottic Stenosis Surgical Management

The Laryngoscope, EarlyView.
This international cross‐sectional survey of 193 clinicians across 42 countries reveals substantial global and multidisciplinary variation in the surgical management of idiopathic subglottic stenosis (iSGS). While endoscopic dilation remains near‐universally utilized, practice patterns differ significantly regarding technical execution, adjuvant ...
Emilie A. C. Dronkers, Jip Y. Mulders, Dale Ekbom, Alexander Gelbard, Karla O'Dell, Ricky Thakrar, Ad Verhagen, Chadwan Al Yaghchi   +7 more
wiley   +1 more source

Cytokeratin expression in breast cancer: from mechanisms, progression, diagnosis, and prognosis to therapeutic implications

Molecular & Cellular Oncology
Background and Aim Cytokeratins (CKs) are structural proteins vital to epithelial integrity and play key roles in breast cancer progression. This review explores their expression, functions, and therapeutic potential.Methods A systematic review was ...
Ensiyeh Bahadoran, Sahar Moghbelinejad, Ghazaleh Mohammadi, Hamid Shahbazmohammadi, Zohreh Abdolvahabi, Manijeh Jalilvand, Isareza Zare, Masood Alaei, Sanaz Keshavarz Shahbaz   +8 more
doaj   +1 more source

Immune dysregulation in the prostates of C57BL/6Aire−/− mice mirrors that seen in human benign prostatic hyperplasia

The Journal of Pathology, EarlyView.
Abstract Benign prostatic hyperplasia (BPH) is the most common urologic disease in aging men, resulting in significant morbidity. The etiologies of BPH are unknown, though chronic prostatic inflammation is known to promote hyperplasia, fibrotic remodeling, and therapeutic resistance in BPH.
Nadia A Lanman, Meaghan M Broman, Harish Kothandaraman, Gregory M Cresswell, Gada D Awdalkreem, Dilinaer Wusiman, Andree K Kolliegbo, Alexander P Glaser, Brian T Helfand, Renee E Vickman, Jiang Yang, Simon W Hayward, Timothy L Ratliff   +12 more
wiley   +1 more source

Plasma Proteomics Elucidated a Protein Signature in COVID-19 Patients with Comorbidities and Early-Diagnosis Biomarkers

Biomedicines
Despite great scientific efforts, deep understanding of coronavirus-19 disease (COVID-19) immunopathology and clinical biomarkers remains a challenge. Pre-existing comorbidities increase the mortality rate and aggravate the exacerbated immune response ...
Víctor Urbiola-Salvador, Suiane Lima de Souza, Katarzyna Macur, Paulina Czaplewska, Zhi Chen   +4 more
doaj   +1 more source

Identification of Novel Interacting Proteins of FUZ and GPR161

PROTEOMICS, EarlyView.
ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar, Anna Battenhouse, Andrew J. Kim, Sung‐Eun Kim   +3 more
wiley   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Single-cell dissection of chronic lung allograft dysfunction reveals convergent and distinct fibrotic mechanisms

JCI Insight
Chronic lung allograft dysfunction (CLAD) is the leading cause of mortality after lung transplantation, yet its molecular mechanisms remain poorly understood.
Yuanqing Yan, Taisuke Kaihou, Emilia Lecuona, Xin Wu, Masahiko Shigemura, Haiying Sun, Chitaru Kurihara, Ruli Gao, Felix L. Nunez-Santana, G.R. Scott Budinger, Ankit Bharat   +10 more
doaj   +1 more source

Keratin 19 and mesenchymal markers for evaluation of epithelial-mesenchymal transition and stem cell niche components in primary biliary cholangitis by sequential elution-stripping multiplex immunohistochemistry. [PDF]

J Histotechnol, 2020
Paulsen JD, Zeck B, Sun K, Simoes C, Theise ND, Chiriboga L.   +5 more
europepmc   +1 more source