Results 171 to 180 of about 53,032 (257)

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Keratinases: microbial sources, mechanisms, and industrial applications in waste valorization. [PDF]

Front Microbiol
Chu Y, Chu S, Hu F, Huang M, Lu H, Liu Z, Shan F, Chen X.   +7 more
europepmc   +1 more source

Photo‐Catalyzed Labeling of Amyloid Deposits in Human Tissue to Proteotype Amyloidosis Diseases

Aggregate, Volume 7, Issue 3, March 2026.
Amyloid‐ID, a ThT‐like photocatalytic probe, enables proteotyping of amyloid deposits by ROS‐mediated protein labeling. Applied to patient biopsies, amyloid‐ID identifies potential fibrinogen‐derived amyloid in laryngeal amyloidosis, revealing a mechanically sensitive fibrillation mechanism linked to vocal cord friction.
Huan Feng, Fangliang Guo, Yan Wang, Meng You, Qiuxuan Xia, Wang Wan, Di Shen, Kaini Shen, Xin Zhang, Wei Li, Yu Liu   +10 more
wiley   +1 more source

Label-free human skin imaging with enhanced molecular contrast via time-resolved fluorescence and advanced phasor analysis. [PDF]

Commun Biol
Ranjit S, Torrado B, Vallmitjana A, Durkin AF, Dvornikov A, Ganesan A, Kelly KM, Balu M.   +7 more
europepmc   +1 more source

Inguinal Dermoid Cyst Associated With Ipsilateral Undescended Testis in an Adolescent Male: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Groin swellings are the most frequent presenting clinical signs, which most frequently arise due to an inguinal hernia or lymphadenopathy. There are also rare congenital lesions, such as dermoid cysts, which can present similarly to common lesions, also leading to a diagnostic challenge.
Muhammad Hassaan Javaid, Muddassir Khalid, Muhammad Sohaib, Fred Segawa   +3 more
wiley   +1 more source

Gapmer Antisense Oligonucleotide Targeting E-Cadherin Rescues Abnormal Keratinization in X-Linked Ichthyosis Models. [PDF]

Biomol Ther (Seoul)
Kwak JH, Kwon TU, Kwon YJ, Park H, Kang YJ, Shin J, Chun YJ.   +6 more
europepmc   +1 more source

The role of vitamin D receptor signaling in hair follicle health and alopecia: Current understanding and therapeutic implications

Journal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
The vitamin D receptor (VDR) regulates hair follicle biology through ligand‐dependent and ligand‐independent mechanisms by heterodimerizing with retinoid X receptor, recruiting coactivator complexes, and activating target genes including Wnt inhibitors, hair keratins, and cell cycle regulators.
Liancheng Guan, Fan Yang, Meijuan Li, Yujia Chen, Zexin Zhao, Hongxia Li, Deping Luo, Qian Li, Yunzhi Chen   +8 more
wiley   +1 more source

Ultrasound-Assisted alkaline hydrolysis of feather keratin using a cup horn sonoreactor. [PDF]

Ultrason Sonochem
Valle Raydan ND, Loquet A, Habenstein B, Kauffmann B, Chatel G, Robles E.   +5 more
europepmc   +1 more source

TRAF7‐Mutated Fibromyxoid Spindle Cell Tumor of Bone: An Osseous Case Expanding the Spectrum of TRAF7‐Mutated Tumors With Over 20 Years Clinical Follow‐Up

Genes, Chromosomes and Cancer, Volume 65, Issue 3, March 2026.
ABSTRACT TRAF7 mutations are a rare occurrence in human cancer and have recently been described in a group of mesenchymal tumors with varying clinical course. Herein, we expand the spectrum of TRAF7‐mutated fibromyxoid spindle cell tumors by reporting the first case to arise in bone.
Laura M. Warmke, Ani Toklu, Spencer M. Richardson, Christopher D. Collier, L. Daniel Wurtz, Lauren M. Ladd, Roman Shrestha, Devin J. Conway   +7 more
wiley   +1 more source

Characterization of Bromelain-Soluble Sheepskin (Ovis aries) Proteins and Effect of In Vitro Gastrointestinal Digestion on Angiotensin Converting Enzyme Inhibition Activity. [PDF]

Food Sci Nutr
Putri DPT, Gallego M, Abidin MZ, Fitriyanto NA, Mora L, Toldrá F, Erwanto Y.   +6 more
europepmc   +1 more source