Results 201 to 210 of about 53,032 (257)

Molecular Regulation of Secondary Hair Follicle Stem Cell by S100a4 in Cashmere Goat. [PDF]

Int J Mol Sci
Liang X, Liu B, Wang J, Liu Y, Wei Y, Yu H, Zhang J, Zhang S, Xue H.   +8 more
europepmc   +1 more source

Postbiotics and Nicotinamide Utilize Distinct Mechanisms to Improve Skin Barrier Integrity, Inflammation, and Keratinocyte Differentiation

Allergy, Volume 81, Issue 3, Page 830-847, March 2026.
Integrating skin barrier measurements with omics and machine learning, we found that postbiotics and NAM regulate skin homeostasis through distinct, strain‐ and dose‐dependent mechanisms. Postbiotics primarily modulate skin barrier function by promoting keratinocyte differentiation and suppressing inflammation.
Yagiz Pat, Duygu Yazici, Huseyn Babayev, Sena Ardicli, Xiangting Bu, Sheri Simmons, Anthony Almada, Christine Avena, Tye Jensen, Raja Dhir, Patrick Westermann, Asuncion Garcia‐Sanchez, Manru Li, Ozge Ardicli, Can Zeyneloglu, Marco Pane, Angela Amoruso, Christoph Messner, Ismail Ogulur, Yasutaka Mitamura, Mubeccel Akdis, Cezmi A. Akdis   +21 more
wiley   +1 more source

Plakoglobin phosphorylation at serine 665 is capable of stabilizing cadherin-mediated adhesion in keratinocytes. [PDF]

JCI Insight
Vielmuth F, Sigmund AM, Egu DT, Hiermaier M, Steinert LS, Moztarzadeh S, Klimkina M, Schikora ME, Rion PM, Schmitt T, Meier K, Ghoreschi K, Horn AK, Radeva MY, Kugelmann D, Waschke J.   +15 more
europepmc   +1 more source

Kdf1 Regulates Molar Cusp Morphogenesis via the PI3K/AKT/mTOR Signalling Axis

Cell Proliferation, Volume 59, Issue 3, March 2026.
Epithelial Kdf1 knockout disrupts molar cusp morphogenesis by promoting inner enamel epithelium proliferation and invagination via PI3K/AKT/mTOR signalling. ABSTRACT Keratinocyte differentiation factor 1 (Kdf1) reportedly plays a significant role in enamel formation.
Jiayu Wang, Miao Yu, Hangbo Liu, Kai Sun, Chenxin Geng, Haochen Liu, Hailan Feng, Yang Liu, Hu Zhao, Dong Han   +9 more
wiley   +1 more source

Visualizing Cytoskeletal Protein Reconstruction of Vulvar Cancer with Surface-Enhanced Raman Spectroscopy and Gold Nanoparticles. [PDF]

ACS Omega
Yokoyama K, Haering K, Mathewson N, Loss P, Lewis JE.   +4 more
europepmc   +1 more source

Adhesion of Immunoglobulins to Band3 Promotes Increased Erythrocyte Sedimentation Rate in Multiple Myeloma

Cell Proliferation, Volume 59, Issue 3, March 2026.
Decreased sialic acid increases the adhesion of RBC membranes to immunoglobulins leading to an increased erythrocyte sedimentation rate (ESR). The increase in reactive oxygen species (ROS) damages the sialic acid glycosyl chains on the surface of RBC membrane proteins, causing the membrane proteins to be overexposed to the plasma environment due to the
Sicheng Bian, Jiangxia Cui, Xialin Zhang, Chongzhi Bai, Yanhong Tan, Zhuanghui Hao, Xingpeng Bu, Changxin Qu, Lili Sun, Leilei Lin, Qi Wang, Zhengrui Li, Xufeng Huang, Hengrui Liu, Ruo Wang, Yinghua Li, Hongwei Wang   +16 more
wiley   +1 more source

Dermal Fibroblasts, Not Keratinocytes, Dominate IL‐17A/TNF‐Driven Inflammation

Experimental Dermatology, Volume 35, Issue 3, March 2026.
ABSTRACT Chronic inflammatory skin diseases such as psoriasis and hidradenitis suppurativa are driven by cytokines, including IL‐17A and TNF. Although biologics targeting these cytokines have transformed therapy, the transcriptional contributions of individual skin‐resident cell types remain unclear, and dermal fibroblasts have been largely overlooked ...
Lejla Svraka, Hakim Ben Abdallah, Trine Bertelsen, Christian Vestergaard, Claus Johansen   +4 more
wiley   +1 more source

Management of Refractory Infections in a Neonate With Severe Generalized Epidermolysis Bullosa Simplex: A Case Report. [PDF]

Cureus
Maekawa M, Yoshida K, Tanese K, Tomita A, Ishiko A.   +4 more
europepmc   +1 more source

A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders

Experimental Dermatology, Volume 35, Issue 3, March 2026.
ABSTRACT Ankyloblepharon‐ectodermal defects‐cleft lip/palate (AEC) is a disorder caused by autosomal‐dominant mutations in the TP63 gene. AEC is characterised by the presence of severe and painful skin erosions that can take years to heal. Current treatment options for these devastating lesions are limited, highlighting the need for new therapeutic ...
Maddison N. Salois, Saiphone Webb, Isaiah A. Proctor, Peter J. Koch, Maranke I. Koster   +4 more
wiley   +1 more source