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Human hair keratin-associated proteins: Sequence regularities and structural implications

Journal of Structural Biology, 2006
In this paper, we undertake a sequence analysis of the human keratin-associated proteins (KAP). This analysis has revealed two fundamental pentapeptide quasi-repeats (A and B) of the form C-C-X-P-X and C-C-X-S/T-S/T, respectively. The A repeats are also commonly found in two subforms A1 and A2, -C-C-Q-P-X and C-C-R-P-X, respectively-similar to those ...
David A D, Parry   +3 more
openaire   +2 more sources

Characterization and polymorphism of Keratin Associated Protein 1.4 gene in goats

Gene, 2013
Keratin-associated proteins (KAPs) are among the main structural components of the animal fibers and form semi-rigid matrix wherein the keratin intermediate filaments (KIFs) are embedded. Variation in the KAP genes has been reported to affect the structure of KAPs and hence fiber characteristics.
R M, Shah   +5 more
openaire   +2 more sources

Characterization and expression analysis of the hair keratin associated protein KAP26.1

British Journal of Dermatology, 2008
Human hair follicle keratin-associated proteins (KAPs) comprise a large multigene family of proteins thought to be responsible for the bundling of keratin intermediate filaments. Recently, four new KAP family members KAP24.1, KAP25.1, KAP26.1 and KAP27.1 were identified from the genome, but the expression of only one, KAP24.1, was investigated and ...
M A, Rogers   +3 more
openaire   +2 more sources

Polymorphism of the ovine keratin-associated protein 1-4 gene (KRTAP1-4)

Molecular Biology Reports, 2009
Keratin-associated proteins (KAPs) are one of the main structural components of the wool fibre and form a semi-rigid matrix in which the keratin intermediate filaments are embedded. Variation in the KAP genes may affect the structure of KAPs and hence wool characteristics.
Gong, H   +2 more
openaire   +3 more sources

Diversity of Trichocyte Keratins and Keratin Associated Proteins

2018
Wool and hair fibres are primarily composed of proteins of which the keratins and keratin associated proteins (KAPs) are the major component. Considerable diversity is known to exist within these two groups of proteins. In the case of the keratins two major families are known, of which there are 11 members in the acidic Type I family and 7 members in ...
openaire   +2 more sources

Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins

2018
Trichocyte keratins differ considerably from their epithelial cousins in having a higher number of cysteine residues, of which the greater proportion are located in the head and tail regions of these proteins. Coupled with this is the presence of a large number of keratin associated proteins in these fibres that are high in their cysteine content, the ...
openaire   +2 more sources

Isolation and Analysis of Keratins and Keratin-Associated Proteins from Hair and Wool

2016
The presence of highly cross-linked protein networks in hair and wool makes them very difficult substrates for protein extraction, a prerequisite for further protein analysis and characterization. It is therefore imperative that these cross-links formed by disulfide bridges are first disrupted for the efficient extraction of proteins.
Santanu, Deb-Choudhury   +2 more
openaire   +2 more sources

Expression patterns of keratin intermediate filament and keratin associated protein genes in wool follicles

Differentiation, 2009
The catalogue of hair keratin intermediate filaments (KIFs) and keratin-associated proteins (KAPs) present in wool follicles is incomplete. The full coding sequences for three novel sheep KIFs (KRT27, KRT35 and KRT38) and one KAP (KRTAP4-3) were established in this study.
Zhidong, Yu   +7 more
openaire   +2 more sources

Variation in the ovine keratin-associated protein 15-1 gene affects wool yield

The Journal of Agricultural Science, 2018
AbstractKeratin-associated proteins (KAPs) are constituents of wool and hair fibres and are believed to play an important role in determining the characteristics of the fibres. In the current study, a polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) approach was used to screen for variation in the ovine KAP15-1 gene ...
W. Li   +7 more
openaire   +2 more sources

Keratin-Associated Protein Nanoparticles as Hemostatic Agents

ACS Applied Nano Materials, 2021
Wei-Fan Lu   +8 more
openaire   +1 more source

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