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Diversity of Trichocyte Keratins and Keratin Associated Proteins
2018Wool and hair fibres are primarily composed of proteins of which the keratins and keratin associated proteins (KAPs) are the major component. Considerable diversity is known to exist within these two groups of proteins. In the case of the keratins two major families are known, of which there are 11 members in the acidic Type I family and 7 members in ...
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Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins
2018Trichocyte keratins differ considerably from their epithelial cousins in having a higher number of cysteine residues, of which the greater proportion are located in the head and tail regions of these proteins. Coupled with this is the presence of a large number of keratin associated proteins in these fibres that are high in their cysteine content, the ...
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Isolation and Analysis of Keratins and Keratin-Associated Proteins from Hair and Wool
2016The presence of highly cross-linked protein networks in hair and wool makes them very difficult substrates for protein extraction, a prerequisite for further protein analysis and characterization. It is therefore imperative that these cross-links formed by disulfide bridges are first disrupted for the efficient extraction of proteins.
Santanu, Deb-Choudhury +2 more
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Differentiation, 2009
The catalogue of hair keratin intermediate filaments (KIFs) and keratin-associated proteins (KAPs) present in wool follicles is incomplete. The full coding sequences for three novel sheep KIFs (KRT27, KRT35 and KRT38) and one KAP (KRTAP4-3) were established in this study.
Zhidong, Yu +7 more
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The catalogue of hair keratin intermediate filaments (KIFs) and keratin-associated proteins (KAPs) present in wool follicles is incomplete. The full coding sequences for three novel sheep KIFs (KRT27, KRT35 and KRT38) and one KAP (KRTAP4-3) were established in this study.
Zhidong, Yu +7 more
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Variation in the ovine keratin-associated protein 15-1 gene affects wool yield
The Journal of Agricultural Science, 2018AbstractKeratin-associated proteins (KAPs) are constituents of wool and hair fibres and are believed to play an important role in determining the characteristics of the fibres. In the current study, a polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) approach was used to screen for variation in the ovine KAP15-1 gene ...
W. Li +7 more
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Diversity of the glycine/tyrosine-rich keratin-associated protein 6 gene (KAP6) family in sheep
Molecular Biology Reports, 2010Keratin-associated proteins (KAPs) are structural components of wool and variation in them may affect wool characteristics. In this study, we used PCR-SSCP to analyse the ovine KAP6 family which encodes glycine and tyrosine-rich KAPs. Five unique PCR-SSCP patterns were detected in the 250 sheep investigated.
Gong, H +2 more
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Mammalian Genome, 2004
We have previously identified a cluster of 16 genes that encode hair-specific proteins, called keratin-associated proteins (KAPs), located on human Chromosome (Chr) 21q22.3. Here, we have identified similar KAP gene clusters in two primates, chimpanzee and baboon.
Kazunori, Shibuya +6 more
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We have previously identified a cluster of 16 genes that encode hair-specific proteins, called keratin-associated proteins (KAPs), located on human Chromosome (Chr) 21q22.3. Here, we have identified similar KAP gene clusters in two primates, chimpanzee and baboon.
Kazunori, Shibuya +6 more
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158 The keratin-associated protein epiplakin is down-regulated in psoriasis
Journal of Investigative Dermatology, 2023H. Kühtreiber +5 more
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Linkage mapping of wool keratin and keratin-associated protein genes in sheep
Mammalian Genome, 1997McLaren, RJ +4 more
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