Results 101 to 110 of about 139,965 (339)

Distinct CTC Specific RNA Profile Enables NSCLC Early Detection and Dynamic Monitoring of Advanced NSCLC

Advanced Science, EarlyView.
A quantitative CTC RNA assay is developed by incorporating multi‐antibody‐based CTC isolation and specific mRNA quantification using RT‐ddPCR. The NSCLC CTC ScoreD demonstrates high accuracy for early‐stage NSCLC detection, significantly outperforming serum CEA. NSCLC CTC ScoreM exhibits a more accurate early‐warning of responses to different therapies
Xiaoyu Wang, Pi Ding, Wenjuan Xu, Lei Qiu, Jing Ren, Yucheng Fei, Zhili Wang, Cheng Li, Yufei Xing, Mingjing Shen, Yawen Zhu, Yun Guo, Na Sun, Renjun Pei, Minhua Shi   +14 more
wiley   +1 more source

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

Advanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu   +37 more
wiley   +1 more source

A Biodegradable Radical Polymer Enables High‐Performance, Physically Transient Organic Memory

Angewandte Chemie, EarlyView.
A stable radical polymer with intrinsic memristivity and on‐demand physical transience is presented. We leverage the nonconjugated nature of the radical polymer for a systematic molecular engineering. The polymer enabled a high‐performance organic memristive device comparable to inorganic transient memory devices, now equipped with additional ...
Jaehyoung Ko, Soeun Kim, Daeun Kim, Taeho Lim, Soyeong Jin, Youngdo Jeong, Yongho Joo, Sangho Cho   +7 more
wiley   +2 more sources

A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma

Advanced Science, EarlyView.
This study utilizes patient‐derived osteosarcoma organoids and CRISPR screening to identify ERCC6 and HNRNPM as key mediators of cisplatin resistance via the PI3K/AKT pathway and BAX alternative splicing. These findings provide novel insights and potential therapeutic targets for overcoming chemoresistance in osteosarcoma.
Ruiling Xu, Sai Zhu, Wenchao Zhang, Haodong Xu, Chao Tu, Honghui Wang, Lu Wang, Na He, Tang Liu, Xiaoning Guo, Xiaolei Ren, Zhihong Li   +11 more
wiley   +1 more source

Keratin

In the ever-evolving landscape of materials science, the pursuit of sustainable and high-performance materials has led to a renewed interest in biopolymer composites. These materials, which blend the natural advantages of biopolymers with the enhanced properties of composite structures, present a promising frontier for innovation across various ...
Mishra, Dinesh Kumar, Khare, Sundaram
openaire   +1 more source

Extraction of Keratin from Chicken Feathers and its Application in the Treatment of Contaminated Water: an Eco-Friendly Approach

Brazilian Archives of Biology and Technology
Chicken feathers that make up 4-6% of total weight of chicken are most influential waste by-product from poultry farm and slaughter. Annual worldwide generation of several tons of feather biomass raise solid waste management concerns.
Sumaira Amin, Moneeza Abbas, Houda Javed, Zahra Asghar, Nadia Ghani, Shabnum Shaheen, Faiza Hassan, Rabia Akram, Hafiza Sana Yousaf   +8 more
doaj   +1 more source

A Novel OsMPK6‐OsMADS47‐PPKL1/3 Module Controls Grain Shape and Yield in Rice

Advanced Science, EarlyView.
OsMADS47 is identified as a key regulator governing rice grain morphology. Phosphorylation‐dependent regulation of its activity directs the development of slender versus round grains, modulating both yield and appearance. This mechanism bridges cellular signaling with transcriptional regulation, establishing a molecular framework for grain optimization.
Jingjing Fang, Yan Chun, Fan Zhang, Tingting Guo, Mengmeng Ren, Jinfeng Zhao, Shoujiang Yuan, Wensheng Wang, Yunhai Li, Xueyong Li   +9 more
wiley   +1 more source

Keratin-based Nanofibres [PDF]

, 2010
There's Plenty of Room at the Bottom" ? this was the title of the lecture Prof. Richard Feynman delivered at California Institute of Technology on December 29, 1959 at the American Physical Society meeting. He considered the possibility to manipulate matter on an atomic scale.
Tonin C, Aluigi A, Varesano A, Vineis C
openaire   +3 more sources

Interaction of Trichomonas vaginalis and Tritrichomonas foetus with keratin: an important role in parasite infection

Memorias do Instituto Oswaldo Cruz, 2011
Trichomonas vaginalis and Tritrichomonas foetus are human and bovine parasites, respectively, that provoke the sexually transmitted disease trichomoniasis. These extracellular parasites adhere to the host epithelial cell surface.
Ricardo Chaves Vilela, Marlene Benchimol
doaj   +1 more source

Local Visible‐Photocatalytic Production of Hydrogen and Warm Heat for Combination Treatment of Pressure Ulcer

Advanced Science, EarlyView.
A novel concept of visible‐photocatalytic hydrogen/warm heat production is proposed for combination treatment of pressure ulcer (PU), and develop a new kind of palladium nanodots‐deposited hydrogen‐doped titanium dioxide nanorods encapsulating hydorgel dressing to receive a high outcome of PU treatment by hydrogen/warm heat synergistically improving ...
Jiawei Zhu, Ting Chen, Wei Fang, Di Zhou, Dalong Ni, Bin Zhao, Yali Yang, Zhuobin Xu, Qianjun He   +8 more
wiley   +1 more source