Results 11 to 20 of about 111,831 (341)

The Study on Biological Function of Keratin 26, a Novel Member of Liaoning Cashmere Goat Keratin Gene Family. [PDF]

open access: yesPLoS ONE, 2016
In our research, we explored the relationship between Keratin 26 and the regulation of fine hair, BMP signaling pathway, MT, FGF5, and IGF-I. The result of hybridization in situ revealed that Keratin 26 was specially expressed in cortex of skin hair ...
Mei Jin   +5 more
doaj   +1 more source

Mechanical properties, and in vitro biocompatibility assessment of biomimetic dual layered keratin/ hydroxyapatite scaffolds

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
A novel biomimetic dual layered keratin/hydroxyapatite (keratin/HA) scaffold was designed using iterative freeze-drying technique. The prepared scaffolds were studied using several analytical techniques to better understand the biological, structural ...
Sandleen Feroz   +5 more
doaj   +1 more source

The keratin network of intermediate filaments regulates keratinocyte rigidity sensing and nuclear mechanotransduction

open access: yesScience Advances, 2021
Keratin defects associated with blistering skin diseases alter force transmission to the nucleus. The keratin network of intermediate filaments provides keratinocytes with essential mechanical strength and resilience, but the contribution to ...
A. Laly   +8 more
semanticscholar   +1 more source

Keratin Biomaterials in Skin Wound Healing, an Old Player in Modern Medicine: A Mini Review

open access: yesPharmaceutics, 2021
Impaired wound healing is a major medical problem. To solve it, researchers around the world have turned their attention to the use of tissue-engineered products to aid in skin regeneration in case of acute and chronic wounds. One of the primary goals of
M. Konop, M. Rybka, Adrian Drapała
semanticscholar   +1 more source

Polycaprolactone strengthening keratin/bioactive glass composite scaffolds with double cross-linking networks for potential application in bone repair

open access: yesJournal of Leather Science and Engineering, 2022
In this study, we aimed at constructing polycaprolactone (PCL) reinforced keratin/bioactive glass composite scaffolds with a double cross-linking network structure for potential bone repair application.
Liying Sun   +5 more
doaj   +1 more source

Keratinization

open access: yesJournal of Investigative Dermatology, 1976
Early studies have already shown that the tonofibrils of malpighian cells consist of a --SH containing fibrous alpha-protein. It was assumed that the highly resistant protective substance, keratin, was formed by the conversion of --SH groups into --S--S--bonds in this protein.
K, Fukuyama   +3 more
openaire   +4 more sources

Keratin dynamics: modeling the interplay between turnover and transport. [PDF]

open access: yesPLoS ONE, 2015
Keratin are among the most abundant proteins in epithelial cells. Functions of the keratin network in cells are shaped by their dynamical organization. Using a collection of experimentally-driven mathematical models, different hypotheses for the turnover
Stéphanie Portet   +4 more
doaj   +1 more source

Efficacy Coefficients Determined Using Nail Permeability and Antifungal Activity in Keratin-Containing Media Are Useful for Predicting Clinical Efficacies of Topical Drugs for Onychomycosis. [PDF]

open access: yesPLoS ONE, 2016
Onychomycosis is difficult to treat topically due to the deep location of the infection under the densely keratinized nail plate. In order to obtain an in vitro index that is relevant to the clinical efficacy of topical anti-onychomycosis drugs, we ...
Yoshiki Matsuda   +5 more
doaj   +1 more source

A Ca2+-Mediated Switch of Epiplakin from a Diffuse to Keratin-Bound State Affects Keratin Dynamics

open access: yesCells, 2022
Keratins exert important structural but also cytoprotective functions. They have to be adaptable to support cellular homeostasis. Epiplakin (EPPK1) has been shown to decorate keratin filaments in epithelial cells and to play a protective role under ...
Sonia Ratajczyk   +4 more
doaj   +1 more source

Halloysite/Keratin Nanocomposite for Human Hair Photoprotection Coating

open access: yesACS Applied Materials and Interfaces, 2020
We propose a novel keratin treatment of human hair by its aqueous mixtures with natural halloysite clay nanotubes. The loaded clay nanotubes together with free keratin produce micrometer-thick protective coating on hair.
G. Cavallaro   +7 more
semanticscholar   +1 more source

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