Results 221 to 230 of about 76,601 (295)

Stealth Drug Delivery of Mouse Serum Albumin‐Coated Paclitaxel‐Loaded Gelatin Nanoparticles for Targeted Cancer Therapy in Mice

open access: yesNano Select, EarlyView.
Our study presents a novel approach to localized cancer therapy by developing mouse serum albumin (MSA)‐coated paclitaxel (PTX)‐loaded gelatin nanoparticles (MSA@PTX‐loaded GNPs) as a stealth drug delivery system. Given the challenges of nanoparticle‐based chemotherapy, including rapid opsonization and limited drug accumulation at tumor sites, our work
Md. Annur Sadman   +10 more
wiley   +1 more source

miR-195-5p Suppresses KRT80 Expression Inducing Cell Cycle Arrest in Colon Cancer. [PDF]

open access: yesCancers (Basel)
Piccinno E   +6 more
europepmc   +1 more source

Activation of PI3K and deletion of p53 in keratin 15‐expressing mouse mammary cells induces tumor heterogeneity and plasticity modeling metaplastic breast cancer

open access: yesThe Journal of Pathology, EarlyView.
Abstract Although relatively rare, metaplastic breast cancer responds poorly to traditional therapies compared to other subtypes. Accordingly, there is a need for novel animal models to understand its pathogenesis and plasticity. Since alterations in PIK3CA and TP53 genes are common in metaplastic breast cancer, we generated a mouse model of ...
Khoa A Nguyen   +11 more
wiley   +1 more source

Teratoid Hepatoblastoma: Clinicopathologic Features and Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Teratoid hepatoblastoma (HB) is a rare histologic subtype of the most common pediatric liver cancer. Understanding of the clinicopathologic features and outcomes of patients with this disease is currently limited. Methods Multi‐institution, retrospective chart review was conducted to compare 20 children with teratoid HB to 129 ...
Brian T. Hickner   +8 more
wiley   +1 more source

Unraveling Dowling-Degos Disease: A Rare Skin Disorder. [PDF]

open access: yesClin Case Rep
Mathur M   +5 more
europepmc   +1 more source

Structural Variability of Pfam Domains Based on Alphafold2 Predictions

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Understanding the biological functions of proteins is one of the main goals of functional genomics. Such understanding will help control and manipulate biological processes to enhance desirable traits, including improved abiotic and biotic stress resistance in humans, animals, plants, and microbes.
Elly Poretsky   +2 more
wiley   +1 more source

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