Results 251 to 260 of about 139,965 (339)
Increased keratin 80 expression predicts poor prognosis and promotes oxaliplatin resistance in gastric cancer. [PDF]
Yang B+6 more
europepmc +1 more source
Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging
Age‐related increases in IGF‐1 expression in the skin accelerate stem cell exhaustion and senescence by impairing SIRT1 function, ultimately driving hair follicle aging. Conversely, activating SIRT1, clearing senescent cells, or adopting dietary restriction can mitigate excessive IGF‐1 signaling and provide a promising strategy to rejuvenate hair ...
Yang Wang+22 more
wiley +1 more source
Niacinamide and its impact on stratum corneum hydration and structure. [PDF]
Sjöberg T+10 more
europepmc +1 more source
Our study projects significant climate change‐induced distribution shifts of a keratin‐feeding beetle Omorgus suberosus, with expansions into higher latitudes in Europe and North America and notable habitat losses in tropical regions by 2100. Ecological niche models predict a global habitat reduction of 9.5% under SSP2–4.5 and 20.8% under SSP5–8.5 ...
Janderson Batista Rodrigues Alencar+4 more
wiley +1 more source
Dysregulation of STS in keratinocytes promotes calcium signaling and differentiation. [PDF]
Kwon TU+4 more
europepmc +1 more source
Fourteen genes, mainly encoding keratins, were commonly differentially expressed in both allergic and non‐allergic individuals after nasal provocation with birch pollen. The nasal provocation in birch pollen‐allergic individuals led to activation of innate immune pathways within 15–30 min and proliferation‐regulatory pathways within 60–120 min.
Srinidhi Sudharson+10 more
wiley +1 more source
Enhancing Diagnosis in Squamous Cell Carcinoma: Non-Invasive Imaging and Multimodal Approach. [PDF]
Negrutiu M+7 more
europepmc +1 more source
MOv18 IgE, the first‐in‐class IgE antibody targeting the cancer antigen folate receptor alpha (FR⍺) showed early signs of efficacy and was well tolerated in a first‐in‐human clinical trial, with transient urticarial skin reactions as the most common toxicity.
Chara Stavraka+28 more
wiley +1 more source
Skin Appendage Proteins of Tetrapods: Building Blocks of Claws, Feathers, Hair and Other Cornified Epithelial Structures. [PDF]
Holthaus KB+3 more
europepmc +1 more source