Results 81 to 90 of about 5,007,843 (284)

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen   +5 more
wiley   +1 more source

Keratin 19 protein expression is an independent predictor of survival in human hepatocellular carcinoma [PDF]

open access: yesEuropean Journal of Gastroenterology & Hepatology, 2015
We aimed to assess the clinicopathological relevance and prognostic significance of expression of the hepatic progenitor cell markers keratin 19 (K19), epithelial cell adhesion molecule (EpCAM) and CD117 (c-KIT) in a White series of hepatocellular carcinoma (HCC).We evaluated the immunohistochemical expression of K19, EpCAM and CD117 in 89 surgical ...
Fatourou E   +10 more
openaire   +4 more sources

Keratin Filaments in the Epithelial Cells of Circumvallate Papillae [PDF]

open access: yes, 1988
P(論文)Keratin filaments of epithelial cells of both the dorsal surface and the trench wall in the circumvallate papillae were studied by conventional electron microscopy and by immunohisto- chemistry using antikeratin antibodies.
小原, 伸子   +5 more
core  

Keratin-positive stromal cells are confined within the elastic lamina of the peritoneal membrane (VVG and pan-keratin).

open access: yes, 2017
Adenocarcinoma of the colon invades the peritoneal membrane with uneven fraying of the elastic fibers of the elastic lamina. At low magnification, the keratin-positive stromal cells appear to extend past the elastic lamina and into the subserosa (A and B,
Jey-Hsin Chen (3830464)   +1 more
core   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

open access: yesAdvanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong   +8 more
wiley   +1 more source

Novel Picornavirus Associated with Avian Keratin Disorder in Alaskan Birds

open access: yesmBio, 2016
Avian keratin disorder (AKD), characterized by debilitating overgrowth of the avian beak, was first documented in black-capped chickadees (Poecile atricapillus) in Alaska.
Maxine Zylberberg   +5 more
doaj   +1 more source

A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells. [PDF]

open access: yesPLoS ONE, 2015
The placenta, a transient organ in human, is essential for pregnancy maintenance and for fetal growth and development. Trophoblast and stromal cells are the main cell types present in human placenta.
Wassim Abou-Kheir   +4 more
doaj   +1 more source

The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties [PDF]

open access: yesJournal of Biological Chemistry, 1998
Keratins (K), the cytoplasmic intermediate filament (IF) proteins of epithelial cells, are encoded by a multigene family and expressed in a tissue- and differentiation-specific manner. In human skin, keratinocytes of the basal layer of epidermis and the outer root sheath of hair follicles express K5 and K14 as their main keratins. A small subpopulation
J, Fradette   +3 more
openaire   +2 more sources

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

open access: yesAdvanced Science, EarlyView.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni   +6 more
wiley   +1 more source

ANTIFUNGAL EFFECT OF GOLD NANOPARTICLES ON FUNGI ISOLATED FROM ONYCHOMYCOSIS PATIENTS [PDF]

open access: yesAl-Azhar Journal of Pharmaceutical Sciences, 2019
Onychomycosis is a widely distributed fungal nail infection which can be caused by dermatophytes, yeasts or non-dermatophytic fungi.  In our study a total of 7 species related to 4 genera were isolated from 50 patients suspected with the fungal nail ...
Aml Sami
doaj   +1 more source

Home - About - Disclaimer - Privacy