Results 151 to 160 of about 5,007,843 (284)

Spatial transcriptomics reveals club cell features and strong CLDN18 expression along the mucinous pathway to invasive mucinous adenocarcinoma

open access: yesThe Journal of Pathology, EarlyView.
Abstract Invasive mucinous adenocarcinoma (IMA) of the lung is a distinct subtype of lung adenocarcinoma with unique clinicopathologic features; however, its histogenesis remains incompletely understood. Although mucinous metaplasia has been suspected as a precursor lesion, direct molecular evidence supporting this progression is limited. In this study,
Joon Young Park   +5 more
wiley   +1 more source

Identification of Novel Interacting Proteins of FUZ and GPR161

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar   +3 more
wiley   +1 more source

Plasma Proteomics Elucidated a Protein Signature in COVID-19 Patients with Comorbidities and Early-Diagnosis Biomarkers

open access: yesBiomedicines
Despite great scientific efforts, deep understanding of coronavirus-19 disease (COVID-19) immunopathology and clinical biomarkers remains a challenge. Pre-existing comorbidities increase the mortality rate and aggravate the exacerbated immune response ...
Víctor Urbiola-Salvador   +4 more
doaj   +1 more source

Prueba 19

open access: yes, 2022
Prueba 19, Prueba 19
core   +1 more source

Using MALDI‐FTICR Mass Spectrometry to Enhance ZooMS Identifications of Pleistocene Bone Fragments Showing Variable Collagen Preservation

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Recent advances in high‐throughput molecular analyses of collagen peptides, especially ZooMS (Zooarchaeology by Mass Spectrometry), have permitted breakthroughs in the analysis of archaeological material that is highly fragmented, a factor that hinders morphological identification.
Pauline Raymond   +8 more
wiley   +1 more source

Foamed Concrete Sealing Materials for Coal Seam Gas Drainage Boreholes: A Review

open access: yesSafety Science and Technology, EarlyView.
This study investigates the sealing performance of foamed concrete in gas drainage boreholes. By comparing leakage pathways (a, c) with sealed systems (b, d), the research demonstrates how foamed concrete effectively fills mining‐induced fractures and resists deformation.
Jiaxing Zou   +6 more
wiley   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

open access: yesVIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro   +6 more
wiley   +1 more source

Single-cell dissection of chronic lung allograft dysfunction reveals convergent and distinct fibrotic mechanisms

open access: yesJCI Insight
Chronic lung allograft dysfunction (CLAD) is the leading cause of mortality after lung transplantation, yet its molecular mechanisms remain poorly understood.
Yuanqing Yan   +10 more
doaj   +1 more source

A Nodule on the Cheek of a Child

open access: yes
JEADV Clinical Practice, EarlyView.
Monika Fida   +5 more
wiley   +1 more source

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