Results 251 to 260 of about 5,007,843 (284)

Patterns of keratins 8, 18 and 19 during gonadal differentiation in the mouse: sex- and time-dependent expression of keratin 19

Differentiation, 1998
The acidic keratins K18 and K19 have been shown to display a sex-specific expression during gonadal differentiation in the rat. To extend these findings, we have undertaken a study of the expression of genes encoding for K18 and K19 and their basic partner K8 in the mouse from 10.5 days of gestation until adulthood, using immunofluorescence, in situ ...
A, Appert, V, Fridmacher, O, Locquet, S, Magre   +3 more
openaire   +2 more sources

Keratin 19 expression in the adult and developing human mammary gland

The Histochemical Journal, 1990
In the adult human mammary gland, most of the luminal epithelial cells express keratin 19 (K19+). However, in some small ducts and terminal ductal lobular units where branching would be expected to occur during pregnancy, the pattern of expression of this keratin is heterogeneous.
J, Bartek, J, Bartkova, J, Taylor-Papadimitriou   +2 more
openaire   +2 more sources

Analysis of Keratin Polypeptides 8 and 19 Variants in Inflammatory Bowel Disease

Clinical Gastroenterology and Hepatology, 2007
Keratin-8 (KRT8)-null mice develop spontaneous colitis and predisposition to liver injury. Human studies show that some KRT8 variants predispose to end-stage liver disease and progression and suggest that such variants might associate with UC or CD. We asked whether mutations in KRT8 or KRT19, the major intestinal keratins, are associated with UC/CD ...
Guo-Zhong, Tao, Pavel, Strnad, Qin, Zhou, Ahmad, Kamal, Leilei, Zhang, Nahid D, Madani, Subra, Kugathasan, Steven R, Brant, Judy H, Cho, M Bishr, Omary, Richard H, Duerr   +10 more
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Keratin 19 in the adult human prostate: tissue and cell culture studies

Cell and Tissue Research, 1996
Keratin 19 is found primarily in simple epithelia. In mammary epithelia, keratin 19 was localized to a subset of luminal cells, suggesting that keratin 19-negative cells may be the proliferative compartment of the secretory cell lineage. The structural and functional similarities of prostate and breast led us to examine keratin 19 expression in the ...
D M, Peehl, R G, Sellers, J E, McNeal
openaire   +2 more sources

The mouse keratin 19-encoding gene: sequence, structure and chromosomal assignment

Gene, 1990
Keratin 19 (K19) is synthesized mainly in embryonic and adult simple epithelia, but has also been found in stratified epithelia as well. K19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is ...
Lussier, M, Filion, M, Compton, J G, Nadeau, J H, Lapointe, L, Royal, A   +5 more
openaire   +2 more sources

Keratin 19-like immunoreactivity in receptor cells of mammalian taste buds

Chemical Senses, 1994
Three monoclonal antibodies, 4.62, LP2K and 170.2.14, were used to evaluate keratin 19-like immunoreactivity in gustatory epithelia. Keratin 19-like immunoreactivity was restricted to the intragemmal cells for all types of mammalian taste buds examined.
L, Wong, B, Oakley, A, Lawton, Y, Shiba
openaire   +2 more sources

Immunohistochemical expression of keratins 8 and 19 in odontogenic cysts and tumors

Journal of Cranio-Maxillary Diseases, 2015
Objective: Cytokeratins (CKs) are integral components in the formation of enamel, dentin and/or cemental matrix and their subsequent mineralization. K8 and K19 are known to be chemically homologous during the formation of tooth structures. This feature is rather unique and is expressed across the milieu of odontogenic tissues in the physiological and ...
VenkateshV Kamath, Komali Yarlagadda, Krishnanand Satelur   +2 more
openaire   +1 more source

Unexpected Low Bone Mass Induced by Global Deletion of Keratin 18 But Not Keratin 19 in Mice

Physiology
Work from our lab has investigated the role of the cytoskeleton in osteoblasts and osteocytes. Our prior work has shown a role for a subset of post-translationally modified tubulin in the osteocyte response to mechanical stimuli and an unexpected role for the type IV intermediate
Philippa Murray, Heather Buck, Katrina LeBlanc, Saimai Chatree, Jenna Leser, Sushrut Pathy, Robert Bloch, Joseph Stains   +7 more
openaire   +1 more source

Keratin 14 protein in cultured nonparenchymal rat hepatic epithelial cells: Characterization of keratin 14 and keratin 19 as antigens for the commonly used mouse monoclonal antibody OV‐6

Molecular Carcinogenesis, 1993
AbstractWe have recently reported that cell lines of nonparenchymal origin isolated from rat liver and pancreas, which have been suggested to be the progeny of a facultative stem cell compartment in vivo, express an unusual combination of keratins (K).
H C, Bisgaard, D C, Parmelee, H A, Dunsford, S, Sechi, S S, Thorgeirsson   +4 more
openaire   +2 more sources

The keratin 19 promoter is potent for cell-specific targeting of genes in transgenic mice

Gastroenterology, 2001
Keratins are intermediate filaments that are critical in cytoskeletal organization. Their roles in cellular processes are underscored by inherited human diseases in which germline mutations of keratins are found, as well as by transgenic and knockout mouse models that recapitulate those diseases.
F H, Brembeck, J, Moffett, T C, Wang, A K, Rustgi   +3 more
openaire   +2 more sources