Results 151 to 160 of about 56,636 (187)

Medullary carcinoma of the breast: a tumour lacking keratin 19

open access: yesHistopathology, 1994
The presence of keratin 19 (K19) was searched for by immunostaining in 16 medullary carcinomas, comprising 12 typical and four atypical cases, in 29 undifferentiated high‐grade carcinomas (NOS‐HG) with conspicuous lymphoid response and in 12 well differentiated low‐grade carcinomas (NOS‐LG).
Larsimont, Denis   +3 more
openaire   +4 more sources

Absence of keratin 19 in mice causes skeletal myopathy with mitochondrial and sarcolemmal reorganization

open access: yesJournal of Cell Science, 2007
Intermediate filaments, composed of desmin and of keratins, play important roles in linking contractile elements to each other and to the sarcolemma in striated muscle. We examined the contractile properties and morphology of fast-twitch skeletal muscle from mice lacking keratin 19.
Michele R, Stone   +9 more
openaire   +3 more sources

Identification of Epithelial Stem Cells In Vivo and In Vitro Using Keratin 19 and BrdU

open access: yes, 2009
Progress in the identification of skin stem cells and the improvement of culture methods open the possibility to use stem cells in regenerative medicine. Based on their quiescent nature, the development of label retention assays allowed the localization of skin stem cells in the bulge region of the pilosebaceous units and in the bottom of rete ridges ...
Germain, Lucie   +4 more
openaire   +4 more sources

The mouse keratin 19-encoding gene: sequence, structure and chromosomal assignment

open access: yesGene, 1990
Keratin 19 (K19) is synthesized mainly in embryonic and adult simple epithelia, but has also been found in stratified epithelia as well. K19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is ...
Lussier, M   +5 more
openaire   +3 more sources
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Patterns of keratins 8, 18 and 19 during gonadal differentiation in the mouse: sex- and time-dependent expression of keratin 19

Differentiation, 1998
The acidic keratins K18 and K19 have been shown to display a sex-specific expression during gonadal differentiation in the rat. To extend these findings, we have undertaken a study of the expression of genes encoding for K18 and K19 and their basic partner K8 in the mouse from 10.5 days of gestation until adulthood, using immunofluorescence, in situ ...
A, Appert   +3 more
openaire   +2 more sources

Keratin 19 expression in the adult and developing human mammary gland

The Histochemical Journal, 1990
In the adult human mammary gland, most of the luminal epithelial cells express keratin 19 (K19+). However, in some small ducts and terminal ductal lobular units where branching would be expected to occur during pregnancy, the pattern of expression of this keratin is heterogeneous.
J, Bartek   +2 more
openaire   +2 more sources

Keratin 19 in the adult human prostate: tissue and cell culture studies

Cell and Tissue Research, 1996
Keratin 19 is found primarily in simple epithelia. In mammary epithelia, keratin 19 was localized to a subset of luminal cells, suggesting that keratin 19-negative cells may be the proliferative compartment of the secretory cell lineage. The structural and functional similarities of prostate and breast led us to examine keratin 19 expression in the ...
D M, Peehl, R G, Sellers, J E, McNeal
openaire   +2 more sources

Keratin 19-like immunoreactivity in receptor cells of mammalian taste buds

Chemical Senses, 1994
Three monoclonal antibodies, 4.62, LP2K and 170.2.14, were used to evaluate keratin 19-like immunoreactivity in gustatory epithelia. Keratin 19-like immunoreactivity was restricted to the intragemmal cells for all types of mammalian taste buds examined.
L, Wong, B, Oakley, A, Lawton, Y, Shiba
openaire   +2 more sources

Analysis of Keratin Polypeptides 8 and 19 Variants in Inflammatory Bowel Disease

Clinical Gastroenterology and Hepatology, 2007
Keratin-8 (KRT8)-null mice develop spontaneous colitis and predisposition to liver injury. Human studies show that some KRT8 variants predispose to end-stage liver disease and progression and suggest that such variants might associate with UC or CD. We asked whether mutations in KRT8 or KRT19, the major intestinal keratins, are associated with UC/CD ...
Guo-Zhong, Tao   +10 more
openaire   +2 more sources

Immunohistochemical expression of keratins 8 and 19 in odontogenic cysts and tumors

Journal of Cranio-Maxillary Diseases, 2015
Objective: Cytokeratins (CKs) are integral components in the formation of enamel, dentin and/or cemental matrix and their subsequent mineralization. K8 and K19 are known to be chemically homologous during the formation of tooth structures. This feature is rather unique and is expressed across the milieu of odontogenic tissues in the physiological and ...
VenkateshV Kamath   +2 more
openaire   +1 more source

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