Results 121 to 130 of about 74,447 (392)

PRED-CLASS: cascading neural networks for generalized protein classification and genome-wide applications

, 2001
A cascading system of hierarchical, artificial neural networks (named PRED-CLASS) is presented for the generalized classification of proteins into four distinct classes-transmembrane, fibrous, globular, and mixed-from information solely encoded in their ...
Adams, Aloy, Apweiler, Bairoch, Brenner, Fariselli, Fariselli, Finkelstein, Fischer, Hamodrakas, Haykin, Hobohm, Jones, Koehl, Levitt, Minsky, Murzin, Murzin, Murzin, Möeller, Nielsen, Pasquier, Pasquier, Pasquier, Pedersen, Petersen, Rice, Rost, Rost, Rumelhart, Sanchez, Schulz, Stevens, Vlahou, Wallin   +34 more
core   +1 more source

Local Visible‐Photocatalytic Production of Hydrogen and Warm Heat for Combination Treatment of Pressure Ulcer

Advanced Science, EarlyView.
A novel concept of visible‐photocatalytic hydrogen/warm heat production is proposed for combination treatment of pressure ulcer (PU), and develop a new kind of palladium nanodots‐deposited hydrogen‐doped titanium dioxide nanorods encapsulating hydorgel dressing to receive a high outcome of PU treatment by hydrogen/warm heat synergistically improving ...
Jiawei Zhu, Ting Chen, Wei Fang, Di Zhou, Dalong Ni, Bin Zhao, Yali Yang, Zhuobin Xu, Qianjun He   +8 more
wiley   +1 more source

Keratinases: emerging trends in production and applications as novel multifunctional biocatalysts

Kuwait Journal of Science, 2016
Keratinases are proteolytic enzymes capable of degrading rigid and insoluble keratinous proteins present in skinand appendages. They are produced in the keratinous substrates such as feather, hair, wool, nail, horn and hoof bymicroorganisms.
Isiaka A. Adelere, Agbaje Lateef
doaj  

Orofacial Epidermoid Cysts: A Case Series

Clinical Case Reports
Epidermoid cysts can occur anywhere in the body but are uncommon in the orofacial region, with a 7% incidence in the head and neck and 1.6% in the oral cavity.
Manoj Adhikari, Kanistika Jha, Puja Thapa, Sarita K.C., Padam Raj Neupane, Pratibha Poudel   +5 more
doaj   +1 more source

The New Keratin Nomenclature [PDF]

Journal of Investigative Dermatology, 2006
When the first nomenclature of the keratin protein family was published over 20 years ago, only 19 keratins were thought to exist. Sequencing of the human genome has now revealed that there are 54 keratin genes. As a consequence, the nomenclature needed revision to apply a logical numbering system that includes the more recently identified keratins of ...
openaire   +3 more sources

Monoallelic Mutations in the Translation Initiation Codon of KLHL24 Cause Skin Fragility [PDF]

, 2016
The genetic basis of epidermolysis bullosa, a group of genetic disorders characterized by the mechanically induced formation of skin blisters, is largely known, but a number of cases still remain genetically unsolved.
Boerries, Melanie, Busch, Hauke, Castiglia, Daniele, Hannula-Jouppi, Katariina, Has, Cristina, Hausser, Ingrid, He, Yinghong, Heikkilä, Hannele, Kiritsi, Dimitra, Leppert, Juna, Maier, Kristin, Schwieger-Briel, Agnes, Tasanen, Kaisa, Theiler, Martin, Weibel, Lisa, Zambruno, Giovanna   +15 more
core   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

Advanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez, Maria Virginia Giolito, Sultan Al‐Siyabi, Kristian Serafimov, Florine Laloux, Emeline Dierge, Léo Aubert, Céline Guilbaud, Selena Kaye, Paula Varon, Dorothée Marchand, Hanne Vlieghe, Emmanuel Hermans, Caroline Bouzin, Davide Brusa, Christiani Andrade Amorim, Barabara Pachikian, Yvan Larondelle, Cyril Corbet, Chantal Dessy, Olivier Feron   +20 more
wiley   +1 more source

Evolutionary origin of Hoxc13-dependent skin appendages in amphibians

Nature Communications
Cornified skin appendages, such as hair and nails, are major evolutionary innovations of terrestrial vertebrates. Human hair and nails consist largely of special intermediate filament proteins, known as hair keratins, which are expressed under the ...
Marjolein Carron, Attila Placido Sachslehner, Munevver Burcu Cicekdal, Inge Bruggeman, Suzan Demuynck, Bahar Golabi, Elfride De Baere, Wim Declercq, Erwin Tschachler, Kris Vleminckx, Leopold Eckhart   +10 more
doaj   +1 more source

A human keratin 10 knockout causes recessive epidermolytic hyperkeratosis [PDF]

, 2017
Epidermolytic hyperkeratosis (EHK) is a blistering skin disease inherited as an autosomal-dominant trait. The disease is caused by genetic defects of the epidermal keratin K1 or K10, leading to an impaired tonofilament network of differentiating ...
Arin, Meral J., Hausser, Ingrid, Hohl, Daniel, Huber, Marcel, Kinaciyan, Tamar, Korge, Bernhard P., Krieg, Thomas, Müller, Felix B., Schaffrath, Christina   +8 more
core  

Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70‐Mediated Stabilization of CLTC During Oocyte meiosis

Advanced Science, EarlyView.
Meiosis is a specialized form of cell division that has different regulation and mechanisms with mitosis in numerous aspects. Particularly, meiosis I is unique and occurs only in germ cells to separate homologous chromosomes. Thus, determining how this unusual chromosome segregation behavior is established is central to understanding germ cell ...
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
wiley   +1 more source